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Volumn 172, Issue 1, 2006, Pages 113-125

Growth defect and mutator phenotypes of RecQ-deficient Neurospora crassa mutants separately result from homologous recombination and nonhomologous end joining during repair of DNA double-strand breaks

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; RAD51 PROTEIN; RECQ HELICASE;

EID: 33644769174     PISSN: 00166731     EISSN: 00166731     Source Type: Journal    
DOI: 10.1534/genetics.105.041756     Document Type: Article
Times cited : (13)

References (64)
  • 1
    • 0024058351 scopus 로고
    • Genetic control of intrachromosomal recombination in Saccharomyces cerevisiae. I. Isolation and genetic characterization of hyper-recombination mutations
    • AGUILERA, A., and H. L. KLEIN, 1988 Genetic control of intrachromosomal recombination in Saccharomyces cerevisiae. I. Isolation and genetic characterization of hyper-recombination mutations. Genetics 119: 779-790.
    • (1988) Genetics , vol.119 , pp. 779-790
    • Aguilera, A.1    Klein, H.L.2
  • 2
    • 0032540283 scopus 로고    scopus 로고
    • Purification and characterization of the Sgs1 DNA helicase activity of Saccharomyces cerevisiae
    • BENNETT, R. J., J. A. SHARP and J. C. WANG, 1998 Purification and characterization of the Sgs1 DNA helicase activity of Saccharomyces cerevisiae. J. Biol. Chem. 273: 9644-9650.
    • (1998) J. Biol. Chem. , vol.273 , pp. 9644-9650
    • Bennett, R.J.1    Sharp, J.A.2    Wang, J.C.3
  • 3
    • 0033523001 scopus 로고    scopus 로고
    • Binding specificity determines polarity of DNA unwinding by the Sgs1 protein of S. cerevisiae
    • BENNETT, R. J., J. L. KECK and J. C. WANG, 1999 Binding specificity determines polarity of DNA unwinding by the Sgs1 protein of S. cerevisiae. J. Mol. Biol. 289: 235-248.
    • (1999) J. Mol. Biol. , vol.289 , pp. 235-248
    • Bennett, R.J.1    Keck, J.L.2    Wang, J.C.3
  • 4
    • 0040436076 scopus 로고    scopus 로고
    • Functional and physical interaction between WRN helicase and human replication protein A
    • BROSH, R. M., JR., D. K. ORREN, J. O.NEHLIN, P.H. RAVN, M. K.KENNY et al., 1999 Functional and physical interaction between WRN helicase and human replication protein A. J. Biol. Chem. 274: 18341-18350.
    • (1999) J. Biol. Chem. , vol.274 , pp. 18341-18350
    • Brosh Jr., R.M.1    Orren, D.K.2    Nehlin, J.O.3    Ravn, P.H.4    Kenny, M.K.5
  • 5
    • 0035887046 scopus 로고    scopus 로고
    • Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity
    • BROSH, R. M., JR., C. VON KOBBE, J. A. SOMMERS, P. KARMAKAR, P. L. OPRESKO et al., 2001 Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity. EMBO J. 20: 5791-5801.
    • (2001) EMBO J. , vol.20 , pp. 5791-5801
    • Brosh Jr., R.M.1    Von Kobbe, C.2    Sommers, J.A.3    Karmakar, P.4    Opresko, P.L.5
  • 6
    • 0346351375 scopus 로고
    • A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes
    • USA
    • CHAGANTI, R. S., S. SCHONBERG and J. GERMAN, 1974 A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes. Proc. Natl. Acad. Sci. USA 71: 4508-4512.
    • (1974) Proc. Natl. Acad. Sci. , vol.71 , pp. 4508-4512
    • Chaganti, R.S.1    Schonberg, S.2    German, J.3
  • 7
    • 0033579344 scopus 로고    scopus 로고
    • Posttranscriptional gene silencing in Neurospora by a RecQ DNA helicase
    • COGONI, C., and G. MACINO, 1999 Posttranscriptional gene silencing in Neurospora by a RecQ DNA helicase. Science 286: 2342-2344.
    • (1999) Science , vol.286 , pp. 2342-2344
    • Cogoni, C.1    Macino, G.2
  • 8
    • 0034231844 scopus 로고    scopus 로고
    • Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest
    • CONSTANTINOU, A., M. TARSOUNAS, J. K. KAROW, R. M. BROSH, V. A. BOHR et al., 2000 Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest. EMBO Rep. 1: 80-84.
    • (2000) EMBO Rep. , vol.1 , pp. 80-84
    • Constantinou, A.1    Tarsounas, M.2    Karow, J.K.3    Brosh, R.M.4    Bohr, V.A.5
  • 9
    • 77956995235 scopus 로고
    • Genetic and microbiological research techniques for Neurospora crassa
    • DAVIS, R. H., and F. J. DE SERRES, 1970 Genetic and microbiological research techniques for Neurospora crassa. Methods Enzymol. 17: 79-143.
    • (1970) Methods Enzymol. , vol.17 , pp. 79-143
    • Davis, R.H.1    De Serres, F.J.2
  • 10
    • 0345486555 scopus 로고
    • A direct method for determination of forward-mutation rates in Neurospora crassa
    • DE SERRES, F. J., and H. G. KLMARK, 1958 A direct method for determination of forward-mutation rates in Neurospora crassa. Nature 182: 1249-1250.
    • (1958) Nature , vol.182 , pp. 1249-1250
    • De Serres, F.J.1    Klmark, H.G.2
  • 11
    • 0034213973 scopus 로고    scopus 로고
    • Partial suppression of the fission yeast rqh1(-) phenotype by expression of a bacterial Holliday junction resolvase
    • DOE, C. L., J. DIXON, F.OSMAN and M. C. WHITBY, 2000 Partial suppression of the fission yeast rqh1(-) phenotype by expression of a bacterial Holliday junction resolvase. EMBO J. 19: 2751-2762.
    • (2000) EMBO J. , vol.19 , pp. 2751-2762
    • Doe, C.L.1    Dixon, J.2    Osman, F.3    Whitby, M.C.4
  • 12
    • 0034713244 scopus 로고    scopus 로고
    • Cell cycle regulation of the endogenous wild-type Bloom's syndrome DNA helicase
    • DUTERTRE, S., M. ABABOU, R. ONCLERCQ, J. DELIC, B. CHATTON et al., 2000 Cell cycle regulation of the endogenous wild-type Bloom's syndrome DNA helicase. Oncogene 19: 2731-2738.
    • (2000) Oncogene , vol.19 , pp. 2731-2738
    • Dutertre, S.1    Ababou, M.2    Onclercq, R.3    Delic, J.4    Chatton, B.5
  • 13
    • 0028785586 scopus 로고
    • The Bloom's syndrome gene product is homologous to RecQ helicases
    • ELLIS, N. A., J. GRODEN, T. Z. YE, J. STRAUGHEN, D. J. LENNON et al., 1995 The Bloom's syndrome gene product is homologous to RecQ helicases. Cell 83: 655-666.
    • (1995) Cell , vol.83 , pp. 655-666
    • Ellis, N.A.1    Groden, J.2    Ye, T.Z.3    Straughen, J.4    Lennon, D.J.5
  • 14
    • 0013907774 scopus 로고
    • Werner's syndrome: A review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process
    • EPSTEIN, C. J., G. M. MARTIN, A. L. SCHULTZ and A. G. MOTULSKY, 1966 Werner's syndrome: a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process. Medicine 45: 177-221.
    • (1966) Medicine , vol.45 , pp. 177-221
    • Epstein, C.J.1    Martin, G.M.2    Schultz, A.L.3    Motulsky, A.G.4
  • 15
    • 0033957793 scopus 로고    scopus 로고
    • The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci
    • FREI, C., and S. M. GASSER, 2000 The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci. Genes Dev. 14: 81-96.
    • (2000) Genes Dev. , vol.14 , pp. 81-96
    • Frei, C.1    Gasser, S.M.2
  • 16
    • 0024465870 scopus 로고
    • Mutator phenotype of Werner syndrome is characterized by extensive deletions
    • USA
    • FUKUCHI, K., G. M. MARTIN and R. J. MONNAT, JR., 1989 Mutator phenotype of Werner syndrome is characterized by extensive deletions. Proc. Natl. Acad. Sci. USA 86: 5893-5897.
    • (1989) Proc. Natl. Acad. Sci. , vol.86 , pp. 5893-5897
    • Fukuchi, K.1    Martin, G.M.2    Monnat Jr., R.J.3
  • 17
    • 0034119866 scopus 로고    scopus 로고
    • Homologous recombination is responsible for cell death in the absence of the Sgs1 and Srs2 helicases
    • GANGLOFF, S., C. SOUSTELLE and F. FABRE, 2000 Homologous recombination is responsible for cell death in the absence of the Sgs1 and Srs2 helicases. Nat. Genet. 25: 192-194.
    • (2000) Nat. Genet. , vol.25 , pp. 192-194
    • Gangloff, S.1    Soustelle, C.2    Fabre, F.3
  • 18
    • 85047695296 scopus 로고    scopus 로고
    • Increased error-prone non homologous DNA end-joining - A proposed mechanism of chromosomal instability in Bloom's syndrome
    • GAYMES, T. J., P. S. NORTH, N. BRADY, I.D.HICKSON, G. J.MUFTI et al., 2002 Increased error-prone non homologous DNA end-joining - a proposed mechanism of chromosomal instability in Bloom's syndrome. Oncogene 21: 2525-2533.
    • (2002) Oncogene , vol.21 , pp. 2525-2533
    • Gaymes, T.J.1    North, P.S.2    Brady, N.3    Hickson, I.D.4    Mufti, G.J.5
  • 19
    • 0027331383 scopus 로고
    • Bloom syndrome: A Mendelian prototype of somatic mutational disease
    • GERMAN, J., 1993 Bloom syndrome: a Mendelian prototype of somatic mutational disease. Medicine 72: 393-406.
    • (1993) Medicine , vol.72 , pp. 393-406
    • German, J.1
  • 20
    • 0021346715 scopus 로고
    • Isolation and characterization of MMS-sensitive mutants of Neurospora crassa
    • INOUE, H., and C. ISHII, 1984 Isolation and characterization of MMS-sensitive mutants of Neurospora crassa. Mutat. Res. 125: 185-194.
    • (1984) Mutat. Res. , vol.125 , pp. 185-194
    • Inoue, H.1    Ishii, C.2
  • 21
    • 0027984149 scopus 로고
    • Mutagenesis and epistatic grouping of the Neurospora meiotic mutants, mei-2 and mei-3, which are sensitive to mutagens
    • ISHII, C., and H. INOUE, 1994 Mutagenesis and epistatic grouping of the Neurospora meiotic mutants, mei-2 and mei-3, which are sensitive to mutagens. Mutat. Res. 315: 249-259.
    • (1994) Mutat. Res. , vol.315 , pp. 249-259
    • Ishii, C.1    Inoue, H.2
  • 22
    • 0031686988 scopus 로고    scopus 로고
    • A new UV-sensitive mutant that suggests a second excision repair pathway in Neurospora crassa
    • ISHII, C., K. NAKAMURA and H. INOUE, 1998 A new UV-sensitive mutant that suggests a second excision repair pathway in Neurospora crassa. Mutat. Res. 408: 171-182.
    • (1998) Mutat. Res. , vol.408 , pp. 171-182
    • Ishii, C.1    Nakamura, K.2    Inoue, H.3
  • 23
    • 2442680431 scopus 로고    scopus 로고
    • Physical and functional interaction between the Bloom's syndrome gene product and the largest subunit of chromatin assembly factor 1
    • JIAO, R., C. Z. BACHRATI, G. PEDRAZZI, P. KUSTER, M. PETKOVIC et al., 2004 Physical and functional interaction between the Bloom's syndrome gene product and the largest subunit of chromatin assembly factor 1. Mol. Cell. Biol. 24: 4710-4719.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 4710-4719
    • Jiao, R.1    Bachrati, C.Z.2    Pedrazzi, G.3    Kuster, P.4    Petkovic, M.5
  • 24
    • 0034712726 scopus 로고    scopus 로고
    • Functional interaction between the Werner Syndrome protein and DNA polymerase delta
    • USA
    • KAMATH-LOEB, A. S., E. JOHANSSON, P. M. BURGERS and L. A. LOEB, 2000 Functional interaction between the Werner Syndrome protein and DNA polymerase delta. Proc. Natl. Acad. Sci. USA 97: 4603-4608.
    • (2000) Proc. Natl. Acad. Sci. , vol.97 , pp. 4603-4608
    • Kamath-Loeb, A.S.1    Johansson, E.2    Burgers, P.M.3    Loeb, L.A.4
  • 25
    • 0034612333 scopus 로고    scopus 로고
    • The Bloom's syndrome gene product promotes branch migration of Holliday junctions
    • USA
    • KAROW, J. K., A. CONSTANTINOU, J. L.LI, S.C.WEST and I. D.HICKSON, 2000 The Bloom's syndrome gene product promotes branch migration of Holliday junctions. Proc. Natl. Acad. Sci. USA 97: 6504-6508.
    • (2000) Proc. Natl. Acad. Sci. , vol.97 , pp. 6504-6508
    • Karow, J.K.1    Constantinou, A.2    Li, J.L.3    West, S.C.4    Hickson, I.D.5
  • 26
    • 1242274561 scopus 로고    scopus 로고
    • The Neurospora crassa mus-19 gene is identical to the qde-3 gene, which encodes a RecQ homologue and is involved in recombination repair and postreplication repair
    • KATO, A., Y. AKAMATSU, Y. SAKURABA and H. INOUE, 2004 The Neurospora crassa mus-19 gene is identical to the qde-3 gene, which encodes a RecQ homologue and is involved in recombination repair and postreplication repair. Curr. Genet. 45: 37-44.
    • (2004) Curr. Genet. , vol.45 , pp. 37-44
    • Kato, A.1    Akamatsu, Y.2    Sakuraba, Y.3    Inoue, H.4
  • 27
    • 0034726966 scopus 로고    scopus 로고
    • Differential regulation of human RecQ family helicases in cell transformation and cell cycle
    • KAWABE, T., N. TSUYAMA, S. KITAO, K. NISHIKAWA, A. SHIMAMOTO et al., 2000 Differential regulation of human RecQ family helicases in cell transformation and cell cycle. Oncogene 19: 4764-4772.
    • (2000) Oncogene , vol.19 , pp. 4764-4772
    • Kawabe, T.1    Tsuyama, N.2    Kitao, S.3    Nishikawa, K.4    Shimamoto, A.5
  • 28
    • 0032535661 scopus 로고    scopus 로고
    • Cloning of two new human helicase genes of the RecQ family: Biological significance of multiple species in higher eukaryotes
    • KITAO, S., I. OHSUGI, K. ICHIKAWA, M. GOTO, Y. FURUICHI et al., 1998 Cloning of two new human helicase genes of the RecQ family: biological significance of multiple species in higher eukaryotes. Genomics 54: 443-452.
    • (1998) Genomics , vol.54 , pp. 443-452
    • Kitao, S.1    Ohsugi, I.2    Ichikawa, K.3    Goto, M.4    Furuichi, Y.5
  • 29
    • 0032939991 scopus 로고    scopus 로고
    • Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome
    • KITAO, S., A. SHIMAMOTO, M. GOTO, R. W. MILLER, W. A. SMITHSON et al., 1999 Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome. Nat. Genet. 22: 82-84.
    • (1999) Nat. Genet. , vol.22 , pp. 82-84
    • Kitao, S.1    Shimamoto, A.2    Goto, M.3    Miller, R.W.4    Smithson, W.A.5
  • 30
    • 0035970893 scopus 로고    scopus 로고
    • Sterility of Drosophila with mutations in the Bloomsyndrome gene: Complementation by Ku70
    • KUSANO, K., D. M. JOHNSON-SCHLITZ and W. R. ENGELS, 2001 Sterility of Drosophila with mutations in the Bloomsyndrome gene: complementation by Ku70. Science 291: 2600-2602.
    • (2001) Science , vol.291 , pp. 2600-2602
    • Kusano, K.1    Johnson-Schlitz, D.M.2    Engels, W.R.3
  • 31
    • 0001313535 scopus 로고
    • The distribution of the numbers of mutants in bacterial populations
    • LEA, D. E., and C. A. COULSON, 1949 The distribution of the numbers of mutants in bacterial populations. J. Genet. 49: 264-285.
    • (1949) J. Genet. , vol.49 , pp. 264-285
    • Lea, D.E.1    Coulson, C.A.2
  • 32
    • 0033621354 scopus 로고    scopus 로고
    • The Werner syndrome gene product co-purifies with the DNA replication complex and interacts with PCNA and topoisomerase I
    • LEBEL, M., E. A. SPILLARE, C. C. HARRIS and P. LEDER, 1999 The Werner syndrome gene product co-purifies with the DNA replication complex and interacts with PCNA and topoisomerase I. J. Biol. Chem. 274: 37795-37799.
    • (1999) J. Biol. Chem. , vol.274 , pp. 37795-37799
    • Lebel, M.1    Spillare, E.A.2    Harris, C.C.3    Leder, P.4
  • 33
    • 0033579343 scopus 로고    scopus 로고
    • Requirement of yeast SGS1 and SRS2 genes for replication and transcription
    • LEE, S. K., R. E. JOHNSON, S. L. YU, L. PRAKASH and S. PRAKASH, 1999 Requirement of yeast SGS1 and SRS2 genes for replication and transcription. Science 286: 2339-2342.
    • (1999) Science , vol.286 , pp. 2339-2342
    • Lee, S.K.1    Johnson, R.E.2    Yu, S.L.3    Prakash, L.4    Prakash, S.5
  • 34
    • 0025302748 scopus 로고
    • An abnormal profile of DNA replication intermediates in Bloom's syndrome
    • LONN, U., S. LONN, U. NYLEN, G.WINBLAD and J. GERMAN, 1990 An abnormal profile of DNA replication intermediates in Bloom's syndrome. Cancer Res. 50: 3141-3145.
    • (1990) Cancer Res. , vol.50 , pp. 3141-3145
    • Lonn, U.1    Lonn, S.2    Nylen, U.3    Winblad, G.4    German, J.5
  • 35
    • 0036850647 scopus 로고    scopus 로고
    • The severe slow growth of Δsrs2 Δrqh1 in Schizosaccharomyces pombe is suppressed by loss of recombination and checkpoint genes
    • MAFTAHI, M., J. C. HOPE, L. DELGADO-CRUZATA, C. S. HAN and G. A. FREYER, 2002 The severe slow growth of Δsrs2 Δrqh1 in Schizosaccharomyces pombe is suppressed by loss of recombination and checkpoint genes. Nucleic Acids Res. 30: 4781-4792.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 4781-4792
    • Maftahi, M.1    Hope, J.C.2    Delgado-Cruzata, L.3    Han, C.S.4    Freyer, G.A.5
  • 36
    • 0036493247 scopus 로고    scopus 로고
    • SGS1 is a multicopy suppressor of srs2: Functional overlap between DNA helicases
    • MANKOURI, H. W., T. J. CRAIG and A. MORGAN, 2002 SGS1 is a multicopy suppressor of srs2: functional overlap between DNA helicases. Nucleic Acids Res. 30: 1103-1113.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 1103-1113
    • Mankouri, H.W.1    Craig, T.J.2    Morgan, A.3
  • 37
    • 0035393720 scopus 로고    scopus 로고
    • The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases
    • MOHAGHEGH, P., J. K. KAROW, R. M. BROSH, JR, V. A. BOHR and I. D. HICKSON, 2001 The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases. Nucleic Acids Res. 29: 2843-2849.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 2843-2849
    • Mohaghegh, P.1    Karow, J.K.2    Brosh Jr., R.M.3    Bohr, V.A.4    Hickson, I.D.5
  • 38
    • 0035158640 scopus 로고    scopus 로고
    • SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, suppresses genome instability and homeologous recombination
    • MYUNG, K., A. DATTA, C. CHEN and R. D. KOLODNER, 2001 SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, suppresses genome instability and homeologous recombination. Nat. Genet. 27: 113-116.
    • (2001) Nat. Genet. , vol.27 , pp. 113-116
    • Myung, K.1    Datta, A.2    Chen, C.3    Kolodner, R.D.4
  • 39
    • 0021719423 scopus 로고
    • Neurospora mutants sensitive both to mutagens and to histidine
    • NEWMEYER, D., 1984 Neurospora mutants sensitive both to mutagens and to histidine. Curr. Genet. 9: 65-74.
    • (1984) Curr. Genet. , vol.9 , pp. 65-74
    • Newmeyer, D.1
  • 40
    • 4344691833 scopus 로고    scopus 로고
    • Highly efficient gene replacements in Neurospora strains deficient for nonhomologous end-joining
    • USA
    • NINOMIYA, Y., K. SUZUKI, C. ISHII and H. INOUE, 2004 Highly efficient gene replacements in Neurospora strains deficient for nonhomologous end-joining. Proc. Natl. Acad. Sci. USA 101: 12248-12253.
    • (2004) Proc. Natl. Acad. Sci. , vol.101 , pp. 12248-12253
    • Ninomiya, Y.1    Suzuki, K.2    Ishii, C.3    Inoue, H.4
  • 41
    • 0034724751 scopus 로고    scopus 로고
    • Elevation of sister chromatid exchange in Saccharomyces cerevisiae sgs1 disruptants and the relevance of the disruptants as a system to evaluate mutations in Bloom's syndrome gene
    • ONODA, F., M. SEKI, A. MIYAJIMA and T. ENOMOTO, 2000 Elevation of sister chromatid exchange in Saccharomyces cerevisiae sgs1 disruptants and the relevance of the disruptants as a system to evaluate mutations in Bloom's syndrome gene. Mutat. Res. 459: 203-209.
    • (2000) Mutat. Res. , vol.459 , pp. 203-209
    • Onoda, F.1    Seki, M.2    Miyajima, A.3    Enomoto, T.4
  • 42
    • 0037081095 scopus 로고    scopus 로고
    • Lack of WRN results in extensive deletion at nonhomologous joining ends
    • OSHIMA, J., S.HUANG, C. PAE, J. CAMPISI and R.H. SCHIESTL, 2002 Lack of WRN results in extensive deletion at nonhomologous joining ends. Cancer Res. 62: 547-551.
    • (2002) Cancer Res. , vol.62 , pp. 547-551
    • Oshima, J.1    Huang, S.2    Pae, C.3    Campisi, J.4    Schiestl, R.H.5
  • 43
    • 0037279866 scopus 로고    scopus 로고
    • The QDE-3 homologue RecQ-2 co-operates with QDE-3 in DNA repair in Neurospora crassa
    • PICKFORD, A., L. BRACCINI, G. MACINO and C. COGONI, 2003 The QDE-3 homologue RecQ-2 co-operates with QDE-3 in DNA repair in Neurospora crassa. Curr. Genet. 42: 220-227.
    • (2003) Curr. Genet. , vol.42 , pp. 220-227
    • Pickford, A.1    Braccini, L.2    Macino, G.3    Cogoni, C.4
  • 44
    • 0026702210 scopus 로고
    • Impaired S-phase transit of Werner syndrome cells expressed in lymphoblastoid cell lines
    • POOT, M.,H.HOEHN, T. M. RUNGER and G. M. MARTIN, 1992 Impaired S-phase transit of Werner syndrome cells expressed in lymphoblastoid cell lines. Exp. Cell Res. 202: 267-273.
    • (1992) Exp. Cell Res. , vol.202 , pp. 267-273
    • Poot, M.1    Hoehn, H.2    Runger, T.M.3    Martin, G.M.4
  • 45
    • 0027942415 scopus 로고
    • Cloning and characterization of RECQL, a potential human homologue of the Escherichia coli DNA helicase RecQ
    • PURANAM, K. L., and P. J. BLACKSHEAR, 1994 Cloning and characterization of RECQL, a potential human homologue of the Escherichia coli DNA helicase RecQ. J. Biol. Chem. 269: 29838-29845.
    • (1994) J. Biol. Chem. , vol.269 , pp. 29838-29845
    • Puranam, K.L.1    Blackshear, P.J.2
  • 46
    • 0027465864 scopus 로고
    • Purification and characterization of the SRS2 DNA helicase of the yeast Saccharomyces cerevisiae
    • RONG, L., and H. L. KLEIN, 1993 Purification and characterization of the SRS2 DNA helicase of the yeast Saccharomyces cerevisiae. J. Biol. Chem. 268: 1252-1259.
    • (1993) J. Biol. Chem. , vol.268 , pp. 1252-1259
    • Rong, L.1    Klein, H.L.2
  • 47
    • 0024407431 scopus 로고
    • Joining of linear plasmid DNA is reduced and error-prone in Bloom's syndrome cells
    • RUNGER, T. M., and K. H. KRAEMER, 1989 Joining of linear plasmid DNA is reduced and error-prone in Bloom's syndrome cells. EMBO J. 8: 1419-1425.
    • (1989) EMBO J. , vol.8 , pp. 1419-1425
    • Runger, T.M.1    Kraemer, K.H.2
  • 48
    • 0028078910 scopus 로고
    • Hypermutable ligation of plasmid DNA ends in cells from patients with Werner syndrome
    • RUNGER, T. M., C. BAUER, B. DEKANT, K. MOLLER, P. SOBOTTA et al., 1994 Hypermutable ligation of plasmid DNA ends in cells from patients with Werner syndrome. J. Invest. Dermatol. 102: 45-48.
    • (1994) J. Invest. Dermatol. , vol.102 , pp. 45-48
    • Runger, T.M.1    Bauer, C.2    Dekant, B.3    Moller, K.4    Sobotta, P.5
  • 49
    • 0019440557 scopus 로고
    • Cytogenetics of Werner's syndrome cultured skin fibroblasts: Variegated translocation mosaicism
    • SALK, D., K. AU, H. HOEHN and G. M. MARTIN, 1981 Cytogenetics of Werner's syndrome cultured skin fibroblasts: variegated translocation mosaicism. Cytogenet. Cell Genet. 30: 92-107.
    • (1981) Cytogenet. Cell Genet. , vol.30 , pp. 92-107
    • Salk, D.1    Au, K.2    Hoehn, H.3    Martin, G.M.4
  • 50
    • 0028061993 scopus 로고
    • Molecular cloning of cDNA encoding human DNA helicase Q1 which has homology to Escherichia coli Rec Q helicase and localization of the gene at chromosome 12p12
    • SEKI, M., H. MIYAZAWA, S. TADA, J. YANAGISAWA, T. YAMAOKA et al., 1994 Molecular cloning of cDNA encoding human DNA helicase Q1 which has homology to Escherichia coli Rec Q helicase and localization of the gene at chromosome 12p12. Nucleic Acids Res. 22: 4566-4573.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 4566-4573
    • Seki, M.1    Miyazawa, H.2    Tada, S.3    Yanagisawa, J.4    Yamaoka, T.5
  • 51
    • 0030820491 scopus 로고    scopus 로고
    • Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants
    • SINCLAIR, D. A., K. MILLS and L. GUARENTE, 1997 Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants. Science 277: 1313-1316.
    • (1997) Science , vol.277 , pp. 1313-1316
    • Sinclair, D.A.1    Mills, K.2    Guarente, L.3
  • 52
    • 0002517129 scopus 로고
    • Use of a bacterial hygromycin B resistance gene as a dominant selectable marker in Neurospora crassa transformation
    • STABEN, C., B. JENSEN, M. SINGER, J. POLLOCK, M. SCHECHTMAN et al., 1989 Use of a bacterial hygromycin B resistance gene as a dominant selectable marker in Neurospora crassa transformation. Fungal Genet. Newsl. 36: 79-81.
    • (1989) Fungal Genet. Newsl. , vol.36 , pp. 79-81
    • Staben, C.1    Jensen, B.2    Singer, M.3    Pollock, J.4    Schechtman, M.5
  • 53
    • 0029915524 scopus 로고    scopus 로고
    • Large deletions at the HPRT locus associated with the mutator phenotype in a Bloom's syndrome lymphoblastoid cell line
    • TACHIBANA, A., K. TATSUMI, T. MASUI and T. KATO, 1996 Large deletions at the HPRT locus associated with the mutator phenotype in a Bloom's syndrome lymphoblastoid cell line. Mol. Carcinogen. 17: 41-47.
    • (1996) Mol. Carcinogen. , vol.17 , pp. 41-47
    • Tachibana, A.1    Tatsumi, K.2    Masui, T.3    Kato, T.4
  • 54
    • 0024439298 scopus 로고
    • Isolation and characterization of a laccase-derepressed mutant of Neurospora crassa
    • TAMARU, H., and H. INOUE, 1989 Isolation and characterization of a laccase-derepressed mutant of Neurospora crassa. J. Bacteriol. 171: 6288-6293.
    • (1989) J. Bacteriol. , vol.171 , pp. 6288-6293
    • Tamaru, H.1    Inoue, H.2
  • 55
    • 0034727684 scopus 로고    scopus 로고
    • Binding and melting of D-loops by the Bloom syndrome helicase
    • VAN BRABANT, A. J., T. YE, M. SANZ, I. J. GERMAN, N. A. ELLIS et al., 2000 Binding and melting of D-loops by the Bloom syndrome helicase. Biochemistry 39: 14617-14625.
    • (2000) Biochemistry , vol.39 , pp. 14617-14625
    • Van Brabant, A.J.1    Ye, T.2    Sanz, M.3    German, I.J.4    Ellis, N.A.5
  • 56
    • 0028896957 scopus 로고
    • Rothmund-Thomson syndrome
    • VENNOS, E. M., and W. D. JAMES, 1995 Rothmund-Thomson syndrome. Dermatol. Clin. 13: 143-150.
    • (1995) Dermatol. Clin. , vol.13 , pp. 143-150
    • Vennos, E.M.1    James, W.D.2
  • 57
    • 0034600976 scopus 로고    scopus 로고
    • Possible association of BLM in decreasing DNA double strand breaks during DNA replication
    • WANG, W., M. SEKI, Y. NARITA, E. SONODA, S. TAKEDA et al., 2000 Possible association of BLM in decreasing DNA double strand breaks during DNA replication. EMBO J. 19: 3428-3435.
    • (2000) EMBO J. , vol.19 , pp. 3428-3435
    • Wang, W.1    Seki, M.2    Narita, Y.3    Sonoda, E.4    Takeda, S.5
  • 58
    • 0037965769 scopus 로고    scopus 로고
    • Functional relation among RecQ family helicases RecQL1, RecQL5, and BLM in cell growth and sister chromatid exchange formation
    • WANG, W., M. SEKI, Y. NARITA, T. NAKAGAWA, A. YOSHIMURA et al., 2003 Functional relation among RecQ family helicases RecQL1, RecQL5, and BLM in cell growth and sister chromatid exchange formation. Mol. Cell. Biol. 23: 3527-3535.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 3527-3535
    • Wang, W.1    Seki, M.2    Narita, Y.3    Nakagawa, T.4    Yoshimura, A.5
  • 60
    • 0030704253 scopus 로고    scopus 로고
    • Genetic and molecular characterization of Neurospora crassa mus-23: A gene involved in recombinational repair
    • WATANABE, K., Y. SAKURABA and H. INOUE, 1997 Genetic and molecular characterization of Neurospora crassa mus-23: a gene involved in recombinational repair. Mol. Gen. Genet. 256: 436-445.
    • (1997) Mol. Gen. Genet. , vol.256 , pp. 436-445
    • Watanabe, K.1    Sakuraba, Y.2    Inoue, H.3
  • 61
    • 0029002965 scopus 로고
    • Sgs1: A eukaryotic homolog of E. coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation
    • WATT, P. M., E. J. LOUIS, R.H. BORTS and I. D. HICKSON, 1995 Sgs1: a eukaryotic homolog of E. coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation. Cell 81: 253-260.
    • (1995) Cell , vol.81 , pp. 253-260
    • Watt, P.M.1    Louis, E.J.2    Borts, R.H.3    Hickson, I.D.4
  • 62
    • 0029657781 scopus 로고    scopus 로고
    • SGS1, a homologue of the Bloom's and Werner's syndrome genes, is required for maintenance of genome stability in Saccharomyces cerevisiae
    • WATT, P. M., I. D. HICKSON, R. H. BORTS and E. J. LOUIS, 1996 SGS1, a homologue of the Bloom's and Werner's syndrome genes, is required for maintenance of genome stability in Saccharomyces cerevisiae. Genetics 144: 935-945.
    • (1996) Genetics , vol.144 , pp. 935-945
    • Watt, P.M.1    Hickson, I.D.2    Borts, R.H.3    Louis, E.J.4
  • 63
    • 0032555220 scopus 로고    scopus 로고
    • Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1mutant: Implication for genomic instability in human diseases
    • USA
    • YAMAGATA, K., J. KATO, A. SHIMAMOTO, M. GOTO, Y. FURUICHI et al., 1998 Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1mutant: implication for genomic instability in human diseases. Proc. Natl. Acad. Sci. USA 95: 8733-8738.
    • (1998) Proc. Natl. Acad. Sci. , vol.95 , pp. 8733-8738
    • Yamagata, K.1    Kato, J.2    Shimamoto, A.3    Goto, M.4    Furuichi, Y.5
  • 64
    • 15844409553 scopus 로고    scopus 로고
    • Positional cloning of the Werner's syndrome gene
    • YU, C. E., J. OSHIMA, Y. H. FU, E. M. WIJSMAN, F. HISAMA et al., 1996 Positional cloning of the Werner's syndrome gene. Science 272: 258-262.
    • (1996) Science , vol.272 , pp. 258-262
    • Yu, C.E.1    Oshima, J.2    Fu, Y.H.3    Wijsman, E.M.4    Hisama, F.5


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