Acute inflammatory syndrome induced by mycophenolate mofetil in a patient following kidney transplantation

American Journal of Transplantation

Volumn 6, Issue 4, 2006, Pages 852-854

  Hochegger, K ^a   Gruber, J ^a   Lhotta, K ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

MMF; PMN; Side effect

Indexed keywords

ACETYLSALICYLIC ACID; AZATHIOPRINE; CYCLOSPORIN A; FLUINDOSTATIN; FORMYLMETHIONYLLEUCYLPHENYLALANINE; FUROSEMIDE; METOPROLOL; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PHORBOL 13 ACETATE 12 MYRISTATE; XIPAMIDE; ALKALINE PHOSPHATASE; C REACTIVE PROTEIN; GAMMA GLUTAMYLTRANSFERASE; MYCOPHENOLATE MOFETIL; REACTIVE OXYGEN METABOLITE;

AGED; ARTHRITIS; ARTICLE; CASE REPORT; CYTOMEGALOVIRUS; DIARRHEA; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEVER; GASTROINTESTINAL DISEASE; HUMAN; KIDNEY FUNCTION; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; LEUKOPENIA; MALE; NEPHRITIS; NEUTROPHIL; PRIORITY JOURNAL; RESPIRATORY BURST; VOMITING; ACUTE INFLAMMATORY SYNDROME; ALKALINE PHOSPHATASE BLOOD LEVEL; DRUG DOSE INCREASE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; INFLAMMATION; LOW DRUG DOSE;

AGED; ANKLE JOINT; ARTHRITIS; FEVER; GRAFT REJECTION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TRANSPLANTATION; MALE; MYCOPHENOLIC ACID; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHILS; RESPIRATORY BURST; SYNDROME; TETRADECANOYLPHORBOL ACETATE;

EID: 33644763222     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2006.01251.x     Document Type: Article

References (10)

1. Halloran P Mathew T Tomlanovich S Groth C Hooftman L Barker C Mycophenolate mofetil in renal allograft recipients: a pooled efficacy analysis of three randomized, double-blind, clinical studies in prevention of rejection. The International Mycophenolate Mofetil Renal Transplant Study Groups Transplantation 1997 63 39 47
2. Meier-Kriesche HU Steffen BJ Hochberg AM et al. Long-term use of mycophenolate mofetil is associated with a reduction in the incidence and risk of late rejection Am J Transplant 2003 3 68 73
3. Sievers TM Rossi SJ Ghobrial RM et al. Mycophenolate mofetil Pharmacotherapy 1997 17 1178 1197
4. Allison AC Eugui EM Mycophenolate mofetil and its mechanisms of action Immunopharmacology 2000 47 85 118
5. Mathew TH A blinded, long-term, randomized multicenter study of mycophenolate mofetil in cadaveric renal transplantation: results at three years. Tricontinental Mycophenolate Mofetil Renal Transplantation Study Group Transplantation 1998 65 1450 1454
6. Maes B Oellerich M Ceuppens JL et al. A new acute inflammatory syndrome related to the introduction of mycophenolate mofetil in patients with Wegener's granulomatosis Nephrol Dial Transplant 2002 17 923 926
7. Rosenkranz AR Templ E Traindl O Heinzl H Zlabinger GJ Reactive oxygen product formation by human neutrophils as an early marker for biocompatibility of dialysis membranes Clin Exp Immunol 1994 98 300 305
8. Harper L Savage CO Pathogenesis of ANCA-associated systemic vasculitis J Pathol 2000 190 349 359
9. Charles LA Falk RJ Jennette JC Reactivity of antineutrophil cytoplasmic autoantibodies with mononuclear phagocytes J Leukoc Biol 1992 51 65 68
10. Falk RJ Terrell RS Charles LA Jennette JC Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in vitro Proc Natl Acad Sci USA 1990 87 4115 4119