Germ-free mice produce high levels of interferon-gamma in response to infection with Leishmania major but fail to heal lesions

Parasitology

Volumn 131, Issue 4, 2005, Pages 477-488

  Oliveira, M R ^a,b   Tafuri, W L ^a   Afonso, L C C ^c   Oliveira, M A P ^a,d   Nicoli, J R ^a   Vieira, E C ^a   Scott, P ^e   Melo, M N ^a   Vieira, L Q ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b FEDERAL UNIVERSITY OF PARAÍBA   (Brazil)

^c FEDERAL UNIVERSITY OF OURO PRETO   (Brazil)

^d FEDERAL UNIVERSITY OF GOIÁS   (Brazil)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Germ free; Gnotobiology; Gnotobiotic; Leishmania major; Leishmaniasis; Microbiota; Th1

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 4;

AMASTIGOTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL SUBPOPULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; GERMFREE ANIMAL; HEALING; HISTOPATHOLOGY; IMMUNE RESPONSE; LEISHMANIA MAJOR; LEISHMANIASIS; MACROPHAGE; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PARASITE; PRIORITY JOURNAL; T LYMPHOCYTE; TH1 CELL;

ANIMALS; CELL CULTURE TECHNIQUES; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; GERM-FREE LIFE; INTERFERON TYPE II; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; MACROPHAGE ACTIVATION; MICE; TH1 CELLS;

ANIMALIA; LEISHMANIA MAJOR;

EID: 33644693458     PISSN: 00311820     EISSN: 14698161     Source Type: Journal    
DOI: 10.1017/S0031182005008073     Document Type: Article

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