Enhanced sensitivity to mitomycin C by abating heat shock protein 70 expression in human bladder cancer cell line of BIU-87

Chinese Medical Journal

Volumn 118, Issue 23, 2005, Pages 1965-1972

  He, Ling Feng ^a   Guan, Kao Peng ^b   Yan, Zheng ^a   Ye, Hai Yun ^a   Xu, Ke Xin ^a   Ren, Liang ^a   Hou, Shu Kun ^a  

^a PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

^b CANCER HOSPITAL   (China)

Author keywords

Antisense oligomers; Apoptosis; Bladder cancer; Heat shock protein 70; Mitomycin C

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; ANTISENSE OLIGONUCLEOTIDE; DNA FRAGMENT; HEAT SHOCK PROTEIN 70; MESSENGER RNA; MITOMYCIN C; ANTISENSE OLIGODEOXYNUCLEOTIDE; MITOMYCIN;

AGAR GEL ELECTROPHORESIS; APOPTOSIS; ARTICLE; BLADDER CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CARCINOGENESIS; CONTROLLED STUDY; DRUG EFFICACY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VIVO STUDY; MOLECULAR CLONING; PROGNOSIS; PROTEIN EXPRESSION; SENSITIVITY ANALYSIS; STAINING; BLADDER TUMOR; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

APOPTOSIS; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MITOMYCIN; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; RNA, MESSENGER; URINARY BLADDER NEOPLASMS;

EID: 33644692515     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Landis SH, Murray T, Bolden S, et al. Cancer statistics. CA Cancer J Clin 1998;48:6-29.
2. Gontero P, Sargent JM, Hopster DJ, et al. Ex vivo chemosensitivity to mitomycin C in bladder cancer and its relationship with P-glycoprotein and apoptotic factors. Anticancer Res 2002;22:4073-4080.
3. Kaasinen E, Rintala E, Hellstrom P, et al. Factors explaining recurrence in patients undergoing chemoimmunotherapy regimens for frequently recurring superficial bladder carcinoma. Eur Urol 2002;42:167-174.
4. Peter A, Andreas B. Molecular aspects of bladder cancer IV: gene therapy of bladder cancer. Eur Urol 2002;41:372-381.
5. Yan JL, Yu LY, Guo LH. Human alpha galactosidase and alpha 1,2 fucosyltransferase concordantly inhibit xenoreactivity of NIH 3T3 cells with human serum. Acta Pharmacol Sin 2003;24:878-884.
6. Yang SP, Song ST, Song HF. Advancements of antisense oligonucleotides in treatment of breast cancer. Acta Pharmacol Sin 2003;24:289-295.
7. Tong Q, Zeng F, Lin C, et al. Growth inhibiting effects of antisense eukaryotic expression vector of proliferating cell nuclear antigene on human bladder cancer cells. Chin Med J 2003;116:1203-1206.
8. Wei YQ, Zhao X, Kariya Y, et al. Inhibition of proliferation and induction of apoptosis by abrogation of heat-shock protein (HSP) 70 expression in tumor cells. Cancer Immunol Immunother 1995;40:73-78.
9. Vargas-Roig LM, Gago FE, Tello O, et al. Heat shock protein expression and drug resistance in breast cancer patients treated with induction chemotherapy. Int J Cancer 1998;79:468-475.
10. Kaur J, Kaur J, Ralhan R. Induction of apoptosis by abrogation of HSP70 expression in human oral cancer cells. Int J Cancer 2000;85:1-5.
11. Kim DJ, Chung JH, Lee JS, et al. Production and characterization of a monoclonal antibody specific to the human 70-kDa heat shock protein. Hybridoma 2000;19:369-374.
12. Seo JS, Park YM, Kim JI, et al. T cell lymphoma in transgenic mice expressing the human HSP70 gene. Biochem Biophys Res Commun 1996;218:582-587.
13. Li XH, Li JJ, Zhang HW, et al. Nimesulide inhibits tumor growth in mice implanted hepatoma: overexpression of Bax over Bcl-21.Acta Pharmacol Sin 2003;24:1045-1050.
14. Zhu Z, Xing S, Lin C, et al. Bladder cancer therapy using combined proliferating cell nuclear antigen antisense oligonucleotides and recombinant adenovirus p53. Chin Med J 2003;116:1860-1863.
15. Zellweger T, Chi K, Miyake H, et al. Enhanced radiation sensitivity in prostate cancer by inhibition of the cell survival protein clusterin. Clin Cancer Res 2002;8:3276-3284.
16. Miyake H, Chi K, Gleave ME. Antisense TRPM-2 oligodeoxynucleotides chemosensitize human androgen-independent PC-3 prostate cancer cells both in vitro and in vivo. Clin Cancer Res 2000;6:1655-1663.
17. Lindquist TA, Craig EA. The heat shock proteins. Annu Rev Genet 1988;22:631-677.
18. Welsh WJ. Mammalian stress response: cell physiology, structure, function of stress proteins, and implications for medicine and diseases. Physiol Rev 1992;72:1063-1069.
19. Sun XF, Zhong H, Carstensen J, et al. Heat shock protein 72/73 in relation to cytoplasmic p53 expression and prognosis in colorectal adenocarcinomas. Int J Cancer 1997;74:600-604.
20. Jesper N, Wolfgang W, Ulrich AH, et al. Eradication of glioblastoma, and breast and colon carcinoma xenografts by hsp70 depletion. Cancer Res 2002;62:7139-7142.
21. Hosokawa N, Hirayoshi K, Kudo H, et al. Inhibition of the activation of heat shock factor in vivo and in vitro by flavanoids. Mol Cell Biol 1992;12:3490-3498.
22. Kim JH, Yeo GS, Lim YS, et al. Supression of multidrug resistance via inhibition heat shock factor by MDR cells. Exp Mol Med 1998;30:87-93.
23. Gabai VL, Zamulaeva IV, Mosin AF, et al. Resistance of Ehrlich tumor cells to apoptosis can be due to accumulation of heat shock proteins. FEBS Lett 1995;375:21-26.
24. Matsumoto H, Wang XJ, Ohnishi T. Binding between wild-type p53 and hsp72 accumulated after UV and ·-ray irradiation. Cancer Lett 1995; 92:127-133.
25. Koskinen PJ, Sistonen L, Evan G, et al. Nuclear colocalization of cellular and viral myc proteins with HSP70 in myc-overexpressing cells. J Virol 1991;65:842-851.
26. Wang CY, Mayo MW, Baldwin AS. TNF-· and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kB. Science 1996;274:784-787.