Validation of in vivo fluorochrome concentrations measured using fluorescence molecular tomography

Journal of Biomedical Optics

Volumn 10, Issue 4, 2005, Pages

  Graves, Edward E ^a   Yessayan, Doreen ^b   Turner, Gordon ^b   Weissleder, Ralph ^b   Ntziachristos, Vasilis ^b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Diffuse optical tomography; Fluorescence molecular tomography; Fluorescent probes; Molecular imaging

Indexed keywords

ABSORPTION; COMPUTER SIMULATION; COMPUTERIZED TOMOGRAPHY; IMPLANTS (SURGICAL); MEDICAL IMAGING; PHOTONS; TUMORS;

DIFFUSE OPTICAL TOMOGRAPHY; FLUORESCENCE MOLECULAR TOMOGRAPHY; FLUOROCHROME CONCENTRATIONS; MOLECULAR IMAGING;

BIOMEDICAL ENGINEERING;

MUS MUSCULUS;

EID: 33644683650     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.1993427     Document Type: Article

References (45)

1. S. Folli, P. Westermann, D. Braichotte, A. Pelegrin, G. Wagnières, H. Van den Berg, and J. P. Mach, "Antibody-indocyanin conjugates for immunophotodetection of human squamous cell carcinoma in nude mice," Cancer Res. 54, 2643-2649 (1994). (Pubitemid 24173752)
2. D. Neri, B. Carnemolla, A. Nissim, A. Leprini, G. Querzè, E. Balza, A. Pini, L. Tarli, C. Halin, P. Neri, L. Zardi, and G. Winter, "Targeting by affinity-matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform," Nat. Biotechnol. 15, 1271-1275 (1997). (Pubitemid 27465138)
3. E. Schellenberger, A. Bogdanov, A. Petrovsky, V. Ntziachristos, R. Weissleder, and L. Josephson, "Optical imaging of apoptosis as a biomarker of tumor response to chemotherapy," Neoplasia 5, 187-192 (2003). (Pubitemid 36754049)
4. S. Achilefu, R. B. Dorshow, J. E. Bugaj, and R. Rajagopalan, "Novel receptor-targeted fluorescent contrast agents for in vivo tumor imaging," Invest. Radiol. 35, 479-485 (2000). (Pubitemid 30622015)
5. A. Becker, C. Hessenius, K. Licha, B. Ebert, U. Sukowski, W Semmler, B. Wiedenmann, and C. Grotzinger, "Receptor-targeted optical imaging of tumors with near-infrared fluorescent ligands," Nat. Biotechnol. 19, 327-331 (2001). (Pubitemid 32275340)
6. R. Weissleder, C. H. Tung, U. Mahmood, and A. Bogdanov, "In vivo imaging of tumors with protease-activated near-infrared fluorescent probes," Nat. Biotechnol. 17, 375-378 (1999). (Pubitemid 29166041)
7. S. Tyagi and F. R. Kramer, "Molecular beacons: probes that fluoresce upon hybridization," Nat. Biotechnol. 14, 303-8 (1996).
8. M. Yang, E. Baranov, P. Jiang, F. Sun, L. Li, S. Hasegawa, M. Bouvet, M. Al-Tuwaijri, T. Chishima, H. Shimada, A. R. Moossa, S. Penman, and R. M. Hoffman, "Whole-body optical imaging of green fluorescent protein-expressing tumors and metastases," Proc. Natl. Acad. Sci. U.S.A. 97, 1206-1211 (2000). (Pubitemid 30080837)
9. M. Rajadhyaksha, M. Grossman, D. Esterowitz, R. H. Webb, and R. R. Anderson, "In vivo confocal laser microscopy of human skin: melanin provides strong contrast," J. Invest. Dermatol. 104, 946-952 (1995).
10. B. R. Masters, P. T. C. So, and E. Gratton, "Multiphoton excitation fluorescence microscopy and spectroscopy of in vivo human skin," Biophys. J. 72, 2405-2412 (1997). (Pubitemid 27227578)
11. S. Gonzalez, M. Rajadhyaksha, G. Rubinstein, and R. R. Anderson, "Characterization of psoriasis in vivo by reflectance confocal microscopy," J. Med. 30, 337-356 (1999). (Pubitemid 30366338)
12. P. T. C. So, C. Y. Dong, B. R. Masters, and K. M. Berland, "Twophoton excitation fluorescence microscopy," Annu. Rev. Biomed. Eng. 2, 399-429 (2000).
13. W. L. Monsky, D. Fukumura, T. Gohongi, M. Ancukiewcz, H. A. Weich, V. P. Torchilin, F Yuan, and R. K. Jain, "Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor," Cancer Res. 59, 4129-4135 (1999). (Pubitemid 29393588)
14. M. Dellian, F Yuan, V. S. Trubetskoy, V. P. Torchilin, and R. K. Jain, "Vascular permeability in a human tumour xenograft: molecular charge dependence," Br. J. Cancer 82, 1513-1518 (2000). (Pubitemid 30204355)
15. U. Mahmood, C. H. Tung, A. Bogdanov, and R. Weissleder, "Near infrared optical imaging system to detect tumor protease activity," Radiology 213, 866-870 (1999).
16. J. S. Reynolds, T. L. Troy, R. H. Mayer, A. B. Thompson, D. J. Waters, K. K. Cornell, P. W Snyder, and E. M. Sevick-Muraca, "Imaging of spontaneous canine mammary tumors using fluorescent contrast agents," Photochem. Photobiol. 70, 87-94 (1999). (Pubitemid 129572619)
17. A. Zaheer, R. E. Lenkinski, A. Mahmood, A. G. Jones, L. C. Cantley, and J. V. Frangioni, "In vivo near-infrared fluorescence imaging of osteoblastic activity," Nat. Biotechnol. 19, 1148-1154 (2001). (Pubitemid 33115701)
18. J. E. Bugaj, S. Achilefu, R. B. Dorshow, and R. Rajagopalan, "Novel fluorescent contrast agents for optical imaging of in vivo tumors based on a receptor-targeted dye-peptide conjugate platform," J. Biomed. Opt. 6, 122-133 (2001). (Pubitemid 32546877)
19. V. Ntziachristos, C. Bremer, and R. Weissleder, "Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging," Eur. Radiol. 13, 195-208 (2003). (Pubitemid 36790510)
20. B. W. Pogue, S. L. Gibbs, B. Chen, and M. Savellano, "Fluorescence imaging in vivo: Raster scanned point-source imaging provides more accurate quantification than broad beam geometries," Technol. Cancer Res. Treat. 3, 15-21 (2004). (Pubitemid 38250464)
21. V. Ntziachristos, E. A. Schellenberger, J. Ripoll, D. Yessayan, E. Graves, A. Bogdanov, L. Josephson, and R. Weissleder, "Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V-Cy 5.5 conjugate," Proc. Natl. Acad. Sci. U.S.A. 101, 12294-12299 (2004). (Pubitemid 39145437)
22. E. L. Hull, M. G. Nichols, and T. H. Foster, "Localization of luminescent inhomogeneities in turbid media with spatially resolved measurements of cw diffuse luminescence emittance," Appl. Opt. 37, 2755-2765 (1998). (Pubitemid 128657587)
23. V. Chenomordik, D. Hattery, I. Gannot, and A. H. Gandjbakhche, "Inverse method 3-D reconstruction of localized in vivo fluorescence - application to Sjogren syndrome," IEEE J. Sel. Top. Quantum Electron. 54, 930-935 (1999). (Pubitemid 30544888)
24. J. H. Chang, H. L. Graber, and R. L. Barbour, "Imaging of fluorescence in highly scattering media," IEEE Trans. Biomed. Eng. 44, 810-822 (1997). (Pubitemid 27357675)
25. J. Wu, L. Perelman, R. R. Dasari, and M. S. Feld, "Fluorescence tomographic imaging in turbid media using early-arriving photons and Laplace transforms," Proc. Natl. Acad. Sci. U.S.A. 94, 8783-8788 (1997). (Pubitemid 27335117)
26. H. Jiang, "Frequency-domain fluorescent diffusion tomography: a finite-element-based algorithm and simulations," Appl. Opt. 37, 5337-5343 (1998). (Pubitemid 128658563)
27. R. Roy and E. M. Sevick-Muraca, "Three-dimensional unconstrained and constrained image-reconstruction techniques applied to fluorescence, frequency-domain photon migration," Appl. Opt. 40, 2206-2215 (2001).
28. V. Ntziachristos and R. Weissleder, "Experimental three-dimensional fluorescence reconstruction of diffuse media using a normalized Born approximation," Opt. Lett. 26, 893-895 (2001). (Pubitemid 33693607)
29. M. J. Eppstein, D. J. Hawrysz, A. Godavarty, and E. M. Sevickmuraca, "Three-dimensional, Bayesian image reconstruction from sparse and noisy data sets: Near-infrared fluorescence tomography," Proc. Natl. Acad. Sci. U.S.A. 99, 9619-9624 (2002). (Pubitemid 34831096)
30. J. Lee and E. M. Sevick-Muraca, "3-D fluorescence enhanced optical tomography using referenced frequency-domain photon migration measurements at emission and excitation measurements," J. Opt. Soc. Am. A 19, 759-771 (2002).
31. E. M. Sevick-Muraca, J. P. Houston, and M. Gurfinkel, "Fluorescence-enhanced, near infrared diagnostic imaging with contrast agents," Curr. Opin. Chem. Biol. 6, 642-650 (2002). (Pubitemid 35284196)
32. V. Ntziachristos and R. Weissleder, "CCD-based scanner for tomography of fluorescent near-infrared probes in turbid media," Med. Phys. 29, 803-809 (2002). (Pubitemid 34525909)
33. A. Godavarty, M. J. Eppstein, C. Zhang, A. B. Thompson, M. Gurfinkel, S. Theru, and E. M. Sevick-Muraca, "Fluorescence-enhanced optical imaging in large tissue volumes using a gain modulated ICCD camera," Phys. Med. Biol. 48, 1701-1720 (2003). (Pubitemid 36805845)
34. E. E. Graves, J. Ripoll, R. Weissleder, and V. Ntziachristos, "A submillimeter resolution fluorescence molecular imaging system for small animal imaging," Med. Phys. 30, 901-911 (2003). (Pubitemid 36578694)
35. A. D. Klose and A. H. Hielscher, "Fluorescence tomography with simulated data based on the equation of radiative transfer," Opt. Lett. 28, 1019-1021 (2003).
36. J. Ripoll, R. Schultz, and V. Ntziachristos, "Free-space propagation of diffuse light: Theory and experiments," Phys. Rev. Lett. 91, 103901-1-4 (2003).
37. A. B. Milstein, J. J. Stott, S. Oh, D. Boas, R. P. Millane, C. A. Bouman, and K. J. Webb, "Fluorescence optical diffusion tomography using multiple-frequency data," J. Opt. Soc. Am. A 21, 1035-1049 (2004).
38. V. Ntziachristos, C. Tung, C. Bremer, and R. Weissleder, "Fluorescence-mediated tomography resolves protease activity in vivo," Nat. Med. 8, 757-760 (2002). (Pubitemid 34778731)
39. E. E. Graves, A. Petrovsky, R. Weissleder, and V. Ntziachristos, "In vivo time-resolved optical spectroscopy of mice," Opt. Soc. Am. Biomed. Opt. Spectroscopy Diagnostics Meeting, pp. 390-392 (2002).
40. A. C. Kak and M. Slaney, Principles of Computerized Tomographic Imaging, IEEE Press, New York (1988).
41. H. Xu, H. Dehghani, and B. W. Pogue, "Near-infrared imaging in the small animal brain: optimization of fiber positions," J. Biomed. Opt. 8, 102-110 (2003).
42. E. E. Graves, J. P. Culver, J. Ripoll, R. Weissleder, and V. Ntziachristos, "Singular-value analysis and optimization of experimental parameters in fluorescence molecular tomography," J. Opt. Soc. Am. A 21, 231-241 (2004).
43. R. Schultz, J. Ripoll, and V. Ntziachristos, "Non-contact optical tomography of turbid media," Opt. Lett. 28, 1701-1703 (2003).
44. B. Brooksby, H. Dehghani, B. W. Pogue, and K. D. Paulsen, "Near infrared (NIR) tomography breast image reconstruction with a priori structural information from MRI: algorithm development for reconstructing heterogeneities," IEEE J. Sel. Top. Quantum Electron. 9, 199-209 (2003).
45. A. D. Klose, V. Ntziachristos, and A. H. Hielscher, "The inverse source problem based on the radiative transfer equation in optical molecular imaging," J. Comput. Phys. 202, 323-345 (2004).