Emergency contraception

Pediatrics

Volumn 116, Issue 4, 2005, Pages 1026-1035

  Klein, Jonathan D ^d   Barratt, Michelle S ^d   Blythe, Margaret J ^d   Diaz, Angela ^d   Rosen, David S ^d   Wibbelsman, Charles J ^d   Hertweck, S Paige ^a   Kaufman, Miriam ^b   Shain, Benjamin ^c   Davis, Ann J ^a   Smith, Karen ^d  

^a AMERICAN COLLEGE OF OBSTETRICIANS AND GYNECOLOGISTS   (United States)

^b CANADIAN PAEDIATRIC SOCIETY   (Canada)

^c American Academy of Child and Adolescent Psychiatry   (United States)

^d NONE

Author keywords

Adolescent pregnancy; Contraception; Emergency contraception

Indexed keywords

CONTRACEPTIVE AGENT; COPPER INTRAUTERINE DEVICE; ETHINYLESTRADIOL; ETHINYLESTRADIOL PLUS LEVONORGESTREL; GESTAGEN; LEVONORGESTREL; NORETHISTERONE; NORGESTREL; POSTCOITUS CONTRACEPTIVE AGENT;

ABDOMINAL PAIN; ADOLESCENT PREGNANCY; BREAST TENDERNESS; DIZZINESS; DRUG SURVEILLANCE PROGRAM; EMERGENCY CONTRACEPTION; FATIGUE; FEMALE; HEADACHE; HEALTH CARE ACCESS; HEALTH CARE POLICY; HUMAN; MENSTRUAL CYCLE; NAUSEA; PRIORITY JOURNAL; REVIEW; TREATMENT CONTRAINDICATION; UNPLANNED PREGNANCY; VAGINA RING; VOMITING; ADOLESCENT; ARTICLE; PRACTICE GUIDELINE; PREGNANCY;

ADOLESCENT; CONTRACEPTIVES, POSTCOITAL, HORMONAL; FEMALE; HUMANS; PREGNANCY; PREGNANCY IN ADOLESCENCE;

EID: 33644676764     PISSN: 00314005     EISSN: 00314005     Source Type: Journal    
DOI: 10.1542/peds.2005-1877     Document Type: Review

References (101)

1. Henshaw SK. Unintended pregnancy in the United States. Fam Plann Perspect. 1998;30:24 -29, 46
2. Pulley L, Klerman LV, Tang H, Baker BA. The extent of pregnancy mistiming and its association with maternal characteristics and behaviors and pregnancy outcomes. Perspect Sex Reprod Health. 2002;34:206-211
3. Ventura SJ, Abma JC, Mosher WD, Henshaw SH. Revised pregnancy rates, 1990-97, and new rates for 1998-99: United States. Natl Vital Stat Rep. 2003;52(7):1-14. Available at: www.cdc.gov/nchs/data/nvsr/nvsr52/nvsr52_07.pdf. Accessed November 29, 2004
4. Hamilton BE, Martin JA, Sutton PD; US Department of Health and Human Services Centers for Disease Control and Prevention. Births: preliminary data for 2002. Natl Vital Stat Rep. 2003;51(11):1-20. Available at: www.cdc.gov/nchs/data/nvsr/nvsr51/nvsr51_11.pdf. Accessed November 30, 2004
5. Jones RK, Darroch JE, Henshaw SK. Patterns in the socioeconomic characteristics of women obtaining abortions in 2000-2001. Perspect Sex Reprod Health. 2002;34:226-235
6. Elam-Evans LD, Strauss LT, Herndon J, et al. Abortion surveillance: United States, 2000. MMWR Surveill Summ. 2003;52(SS-12):1-32. Available at: www.cdc.gov/mmwr/preview/mmwrhtml/ss5212a1.htm. Accessed November 30, 2004
7. Darroch JE, Singh S. Why Is Teenage Pregnancy Declining? The Roles of Abstinence, Sexual Activity and Contraceptive Use. New York, NY: Alan Guttmacher Institute; 1999. Occasional Report 1
8. Boonstra H. Teen pregnancy: trends and lessons learned. Guttmacher Rep Public Policy. 2002;1. Available at: www.agi-usa.org/pubs/ib_1-02.pdf. Accessed November 30, 2004
9. Jones RK, Darroch JE, Henshaw SK. Contraceptive use among US women having abortions in 2000-2001. Perspect Sex Reprod Health. 2002;34:294-303
10. Grunbaum JA, Kann L, Kinchen SA, et al. Youth risk behavior surveillance: United States, 2001. MMWR Surveill Summ. 2002;51(4):1- 64. Available at: www.cdc.gov/mmwr/preview/mmwrhtml/ss5104a1.htm. Accessed November 30, 2004
11. Singh S, Darroch JE. Adolescent pregnancy and childbearing: levels and trends in developed countries. Fam Plann Perspect. 2000;32:14-23
12. Darroch JE, Frost JJ, Singh S, and the Study Team. Teenage Sexual and Reproductive Behavior in Developed Countries: Can More Progress Be Made? New York, NY: Alan Guttmacher Institute; 2001. Occasional Report 3
13. Santelli J, Rochat R, Hatfield-Timajchy K, et al. The measurement and meaning of unintended pregnancy. Perspect Sex Reprod Health. 2003;35:94-101
14. Croxatto HB, Devoto L, Durand M, et al. Mechanism of action of hormonal preparations used for emergency contraception: a review of the literature. Contraception. 2001;63:111-121
15. Glasier A. Emergency postcoital contraception. N Engl J Med. 1997;337:1058-1064
16. Yuzpe AA, Thurlow HJ, Ramzy I, Leyshon JI. Post coital contraception - a pilot study. J Reprod Med. 1974;13:53-58
17. Food and Drug Administration. FDA approves application for Preven emergency contraceptive kit. Available at: www.fda.gov/bbs/topics/ANSWERS/ ANS00892.html. Accessed November 30, 2004
18. Food and Drug Administration, Center for Drug Evaluation and Research. Plan B approval package. Available at: www.fda.gov/cder/foi/nda/99/21-045_PlanB. htm. Accessed November 30, 2004
19. US Food and Drug Administration. Prescription drug products: certain combined oral contraceptives for use as postcoital emergency contraception. Fed Regist. 1997;62:8609.
20. American College of Obstetricians and Gynecologists. ACOG practice bulletin: emergency oral contraception: Number 25, March 2001 (replace Practice Pattern Number 3, December 1996). Int J Gynaecol Obstet. 2002;78:191-198
21. Ellertson C, Webb A, Blanchard K, et al. Modifying the Yuzpe regimen of emergency contraception: a multicenter randomized controlled trial. Obstet Gynecol. 2003;101:1160-1167
22. Yuzpe AA, Lancee WJ. Ethinylestradiol and dl-norgestrel as a postcoital contraceptive. Fertil Steril. 1977;28:932-936
23. Van Santen MR, Haspels AA. Interception II: postcoital low-dose estrogens and norgestrel combination in 633 women. Contraception. 1985;31:275-293
24. Percival-Smith RK, Abercrombie B. Postcoital contraception with dl-norgestrel/ethinyl estradiol combination: six years experience in a student medical clinic. Contraception. 1987;36:287-293
25. Bagshaw SN, Edwards D, Tucker AK. Ethinyl oestradiol and D-norgestrel is an effective emergency postcoital contraceptive: a report of its use in 1,200 patients in a family planning clinic. Aust N Z J Obstet Gynaecol. 1988;28:137-140
26. Trussell J, Ellertson C, Stewart F. The effectiveness of the Yuzpe regimen of emergency contraception [published correction appears in Fam Plann Perspect. 1997;29:60]. Fam Plann Perspect. 1996;28:58-64, 87
27. Trussell J, Rodriguez G, Ellertson C. Updated estimates of the effectiveness of the Yuzpe regimen of emergency contraception. Contraception. 1999;59:147-151
28. Centre for Review and Dissemination. The Yuzpe regimen of emergency contraception: how long after the morning after [abstract 961127]? Database of Abstracts of Review of Effectiveness. 1998
29. Cheng L, Gulmezoglu AM, Oel CJ, Piaggio G, Ezcurra E, Look PF. Interventions for emergency contraception: review. Cochrane Database Syst Rev. 2004;(3):CD001324
30. Zuliani G, Colombo UF, Molla R. Hormonal postcoital contraception with an ethinylestradiol-norgestrel combination and two danazol regimens. Eur J Obstet Gynecol Reprod Biol. 1990;37:253-260
31. Webb AM, Russell J, Elstein M. Comparison of Yuzpe regimen, danazol, and mifepristone (RU486) in oral postcoital contraception. BMJ. 1992;305:927-931
32. Task Force on Postovulatory Methods of Fertility Regulation. Randomised controlled trial of levonorgestrel versus the Yuzpe regimen of combined oral contraceptives for emergency contraception. Lancet. 1998;352:428-433
33. Hatcher RA, Nelson, Zieman M, et al. Emergency contraception. In: Hatcher RA, Nelson, Zieman M, et al. A Pocket Guide to Managing Contraception: 2002-2003 Edition. Tiger, Ga: Bridging the Gap Foundation; 2002:71
34. Raymond EG, Creinin MD, Barnhart KT, Lovvorn AE, Rountree RW, Trussell J. Meclizine for prevention of nausea associated with use of emergency contraceptive pills: a randomized trial. Obstet Gynecol. 2000;95:271-277
35. Ragan RE, Rock RW, Buck HW. Metoclopramide pretreatment attenuates emergency contraceptive-associated nausea. Am J Obstet Gynecol. 2003;188:330-333
36. Ho PC, Kwan MS. A prospective randomized comparison of levonorgestrel with the Yuzpe regimen in post-coital contraception. Hum Reprod. 1993;8:389-392
37. von Hertzen H, Piaggio G, Ding J, et al. Low dose mifepristone and two regimens of levonorgestrel for emergency contraception: a WHO multicentre randomised trial. Lancet. 2002;360:1803-1810
38. Grimes DA, Raymond EG. Emergency contraception. Ann Intern Med. 2002;137:180-189
39. Durand M, del Carmen Cravioto M, Raymond EG, et al. On the mechanisms of action of short-term levonorgestrel administration in emergency contraception. Contraception. 2001;64:227-234
40. Trussell J, Raymond EG. Statistical evidence about the mechanism of action of the Yuzpe regimen of emergency contraception. Obstet Gynecol. 1999;93(5 pt 2):872-876
41. Ling WY, Wrixon W, Acorn T, Wilson E, Collins J. Mode of action of dl-norgestrel and ethinylestradiol combination in postcoital contraception. III. Effect of preovulatory administration following the luteinizing hormone surge on ovarian steroidogenesis. Fertil Steril. 1983;40:631-636
42. Marions L, Hultenby K, Lindell I, Sun X, Stabi B, Gemzell Danielsson K. Emergency contraception with mifepristone and levonorgestrel: mechanism of action. Obstet Gynecol. 2002;100:65-71
43. Swahn ML, Westlund P, Johannisson E, Bygdeman M. Effect of postcoital contraceptive methods on the endometrium and the menstrual cycle. Acta Obstet Gynecol Scand. 1996;75:738-744
44. Croxatto HB, Fuentealba B, Brache V, et al. Effects of the Yuzpe regimen, given during the follicular phase, on ovarian function. Contraception. 2002;65:121-128
45. Wilcox AJ, Weinberg CR, Baird DD. Timing of sexual intercourse in relation to ovulation: effects on the probability of conception, survival of the pregnancy, and sex of the baby. N Engl J Med. 1995;333:1517-1521
46. Wilcox AJ, Dunson D, Baird DD. The timing of the "fertile window" in the menstrual cycle: day specific estimates from a prospective study. BMJ. 2000;321:1259-1262
47. Hapangama D, Glasier AF, Baird DT. The effects of peri-ovulatory administration of levonorgestrel on the menstrual cycle. Contraception. 2001;63:123-129
48. Ling WY, Robichaud A, Zayid I, Wrixon W, MacLeod SC. Mode of action of DL-norgestrel and ethinylestradiol combination in postcoital contraception. Fertil Steril. 1979;32:297-302
49. Kubba AA, White JO, Guillebaud J, Elder MG. The biochemistry of human endometrium after two regimens of postcoital contraception: a dl-norgestrel/ethinylestradiol combination or danazol. Fertil Steril. 1986;45:512-516
50. Rowlands S, Kubba AA, Guillebaud J, Bounds W. A possible mechanism of action of danazol and an ethinylestradiol/norgestrel combination used as postcoital contraceptive agents. Contraception. 1986;33:539-545
51. Kahlenborn C, Stanford JB, Larimore WL. Postfertilzation effect of hormonal emergency contraception. Ann Pharmacother. 2002;36:465-470
52. Taskin O, Brown RW, Young DC, Poindexter AN, Wiehle RD. High doses of oral contraceptives do not alter endometrial α1 and αvβ3 integrins in the late implantation window. Fertil Steril. 1994;61:850-855
53. Landgren BM, Johannisson E, Aedo AR, Kumar A, Shi YE. The effect of levonorgestrel administered in large doses at different stages of the cycle on ovarian function and endometrial morphology. Contraception. 1989;39:275-289
54. Harper CC, Ellertson CE. The emergency contraceptive pill: a survey of knowledge and attitudes among students at Princeton university. Am J Obstet Gynecol. 1995;173:1438-1445
55. Xiao B, Zhao H, Piaggio G, von Hertzen H. Expanded clinical trial of emergency contraception with 10 mg mifepristone. Contraception. 2003;68:431-437
56. Piaggio G, Heng Z, von Hertzen H, Bilian X, Linan C. Combined estimates of effectiveness of mifepristone 10 mg in emergency contraception. Contraception. 2003;68:439-446
57. Stewart FH, Harper CC, Ellertson CE, Grimes DA, Sawaya GF, Trussell J. Clinical breast and pelvic examination requirements for hormonal contraception: current practice vs evidence. JAMA. 2001;285:2232-2239
58. Ellertson C, Evans M, Ferden S, et al. Extending the time limit for starting the Yuzpe regimen of emergency contraception to 120 hours. Obstet Gynecol. 2003;101:1168-1171
59. Rodrigues I, Grou F, Joly J. Effectiveness of emergency contraceptive pills between 72 and 120 hours after unprotected sexual intercourse. Am J Obstet Gynecol. 2001;184:531-537
60. Confidentiality in adolescent health care [reaffirmed January 1993, November 1997, May 2000]. AAP News. 1989;5:9
61. Piaggio G, von Hertzen H, Grimes DA, Van Look PF. Timing of emergency contraception with levonorgestrel or the Yuzpe regimen [letter]. Task Force on Postovulatory Methods of Fertility Regulation. Lancet. 1999;353:721
62. Edozien F. City Council survey: emergency contraception not widely available in New York City, survey finds. New York Post. October 10, 2002:16. Available at: http://pqasb.pqarchiver.com/nypost/208526101.html?did= 208526101&FMT=ABS&FMTS=FT&date=Oct+10%2C+2002&author= FRANKIE+EDOZIEN&desc=GOOD+LUCK+FINDING+MORNING+AFTER%27+PILL. Accessed November 30, 2004
63. Conard LA, Fortenberry JD, Blythe MJ, Orr DP. Pharmacists' attitudes toward and practices with adolescents. Arch Pediatr Adolesc Med. 2003;157:361-365
64. Bennett W, Petraitis C, D'Anella A, Marcella S. Pharmacists' knowledge and the difficulty of obtaining emergency contraception. Contraception. 2003;68:261-267
65. Espey E, Ogburn T, Howard D, Qualls C, Ogburn J. Emergency contraception: pharmacy access in Albuquerque, New Mexico. Obstet Gynecol. 2003;102:918-921
66. Kumar AS, Hall LC, LePage A, Lim PC. Providing emergency contraceptive pills "behind-the-counter": opinions among Minnesota healthcare providers. Contraception. 2003;68:253-259
67. Kaiser Family Foundation. Kaiser daily reproductive health report. Contraception and family planning: FDA advisory panels recommend EC be sold without prescription. December 17, 2003. Available at: www.kaisernetwork.org/ daily_reports/print_report.cfm?DR_ID=21382&dr_cat=2. Accessed November 30, 2004
68. Food and Drug Administration. Nonprescription Drugs Advisory Committee and the Advisory Committee for Reproductive Health Drugs. December 16, 2003. Available at: www.fda.gov/ohrms/dockets/ac/03/briefing/4015b1.htm. Accessed November 30, 2004
69. Food and Drug Administration. FDA issues not approvable letter to Barr Labs: outlines pathway for future approval. Available at: www.fda.gov/bbs/ topics/news/2004/NEW01064.html. Accessed November 30, 2004
70. World Health Organization, Department of Reproductive Health and Research. Improving Access to Quality Care in Family Planning: Medical Eligibility Criteria for Contraceptive Use. 2nd ed. Geneva, Switzerland: World Health Organization; 2000
71. Fabunmi L, Perks N. Caesarean section scar ectopic pregnancy following postcoital contraception. J Fam Plann Reprod Health Care. 2002;28:155-156
72. Harrison-Woolrych ML, Wooley J. Progestogen-only emergency contraception and ectopic pregnancy [editorial]. J Fam Plann Reprod Health Care. 2003;29:5-6
73. Sheffer-Mimouni G, Pauzner D, Maslovitch S, Lessing JB, Gamzu R. Ectopic pregnancies following emergency levonorgestrel contraception. Contraception. 2003;67:267-269
74. Gainer E, Mery C, Ulmann A. Levonorgestrel-only emergency contraception: real-world tolerance and efficacy. Contraception. 2001;64:17-21
75. Bracken MB. Oral contraception and congenital malformations in offspring: a review and meta-analysis of the prospective studies. Obstet Gynecol. 1990;76(3 pt 2):552-557
76. Webb A, Taberner D. Clotting factors after emergency contraception. Adv Contracept. 1993;9:75-82
77. Hatcher RA, Zieman M, Cwiak C, Darney PD, Creinin MD, Stosur HR. Managing Contraception 2004-2005: For Your Pocket. 2004:69-77. Available at: www.managingcontraception.com/cmanager/publish/pocket.shtml. Accessed November 30, 2004
78. Raymond EG, Chen PL, Dalebout SM. "Actual use" study of emergency contraceptive pills provided in a simulated over-the-counter manner. Obstet Gynecol. 2003;102:17-23
79. Gainer E, Blum J, Toverud EL, et al. Bringing emergency contraception over the counter: experiences of nonprescription users in France, Norway, Sweden and Portugal. Contraception. 2003;68:117-124
80. Cohall AT, Dickerson D, Vaughan R, Cohall R. Inner-city adolescents' awareness of emergency contraception. J Am Med Womens Assoc. 1998;53:258-261
81. Kaiser Family Foundation. National Survey of Women Health Care Providers on Reproductive Health: Emergency Contraception. Menlo Park, CA: Kaiser Family Foundation; 2003. Available at: www.kff.org/womenshealth/loader.cfm?url=/ commonspot/security/getfile.cfm&PageID=14303. Accessed August 17, 2005
82. Kosunen E, Sihvo S, Hemminki E. Knowledge and use of hormonal emergency contraception in Finland. Contraception. 1997;55:153-157
83. Glasier A, Ketting E, Ellertson C, Armstrong E. Emergency contraception in the United Kingdom and the Netherlands. Fam Plann Perspect. 1996;28:49-51
84. Boonstra H. Emergency contraception: the need to increase public awareness. Guttmacher Rep Public Policy. 2002:3-6
85. Boonstra H. Emergency contraception: steps being taken to improve access. Guttmacher Rep Public Policy. 2002:10-14
86. Golden NH, Seigel WM, Fisher M, et al. Emergency contraception: pediatricians' knowledge, attitudes, and opinions. Pediatrics. 2001;107:287-292
87. Beckman LJ, Harvey SM, Sherman CA, Petitti DB. Changes in providers' views and practices about emergency contraception with education. Obstet Gynecol. 2001;97:942-946
88. Raine T, Harper C, Leon K, Darney P. Emergency contraception: advance provision in a young, high-risk clinic population. Obstet Gynecol. 2000;96:1-7
89. Gold MA, Wolford JE, Smith KA, Parker AM. The effects of advance provision of emergency contraception on adolescent women's sexual and contraceptive behaviors. J Pediatr Adolesc Gynecol. 2004;17:87-96
90. Graham A, Moore L, Sharp D, Diamond I. Improving teenagers' knowledge of emergency contraception: cluster randomised controlled trial of a teacher led intervention. BMJ. 2002;324:1179
91. McCarthy SK. Availability of emergency contraceptive pills at university and college student health centers. J Am Coll Health. 2002;51:15-22
92. Brening RK, Dalve-Endres AM, Patrick K. Emergency contraception pills (ECPs): current trends in United States college health centers. Contraception. 2003;67:449-456
93. Glasier A, Baird D. The effects of self-administering emergency contraception. N Engl J Med. 1998;339:1-4
94. Ellertson C, Ambardekar S, Hedley A, Coyaji K, Trussell J, Blanchard K. Emergency contraception: randomized comparison of advance provision and information only. Obstet Gynecol. 2001;98:570-575
95. Jackson RA, Bimla Schwartz E, Freedman L, Darney P. Advance supply of emergency contraception. Effect on use and usual contraception - a randomized trial. Obstet Gynecol. 2003;102:8-16
96. Belzer M, Yoshida E, Tejirian T, Tucker D, Chung K, Sanchez K. Advanced supply of emergency contraception for adolescent mothers increased utilization without reducing condom or primary contraception use [abstract]. J Adolesc Health. 2003;32:122-123
97. Blanchard K, Bungay H, Furedi A, Sanders L. Evaluation of an emergency contraception advance provision service. Contraception. 2003;67:343-348
98. American College of Obstetricians and Gynecologists. New ACOG leader promotes widespread advance prescriptions for emergency contraception [press release]. Available at: www.acog.org/from_home/publications/press_releases/nr04- 30-01-1.cfm. Accessed November 30, 2004
99. Sucato GS, Gardner JS, Koepsell TD. Adolescents' use of emergency contraception provided by Washington State pharmacists. J Pediatr Adolesc Gynecol. 2001;14:163-169
100. Rowlands S, Devalia H, Lawrenson R, Logie J, Ineichen B. Repeated use of hormonal emergency contraception by younger women in the UK. Br J Fam Plann. 2000;26:138-143
101. Citizen's petition to Food and Drug Administration, Department of Health and Human Services. February 14, 2001. Available at: www.crlp.org/pdf/ EC_petition.pdf. Accessed June 29, 2005