Geranylgeranylacetone, a noninvasive heat shock protein inducer, induces protein kinase C and leads to neuroprotection against cerebral infarction in rats

Neuroscience Letters

Volumn 396, Issue 3, 2006, Pages 220-224

  Uchida, Susumu ^a   Fujiki, Minoru ^a   Nagai, Yasuyuki ^a   Abe, Tatsuya ^a   Kobayashi, Hidenori ^a  

^a OITA UNIVERSITY   (Japan)

Author keywords

Cerebral ischemia; Geranylgeranylacetone; Heat shock protein 70; Neuroprotection; Protein kinase C

Indexed keywords

CHELERYTHRINE; HEAT SHOCK PROTEIN 70; PROTEIN KINASE C DELTA; PROTEIN KINASE C INHIBITOR; TEPRENONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION; BRAIN INFARCTION SIZE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME INDUCTION; IMMUNOBLOTTING; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ALKALOIDS; ANIMALS; BENZOPHENANTHRIDINES; BLOTTING, WESTERN; CEREBRAL INFARCTION; DISEASE MODELS, ANIMAL; DITERPENES; DRUG INTERACTIONS; ENZYME INHIBITORS; GENE EXPRESSION; HSP70 HEAT-SHOCK PROTEINS; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; NEUROPROTECTIVE AGENTS; PHENANTHRIDINES; PROTEIN KINASE C; RATS; RATS, WISTAR; TETRAZOLIUM SALTS; TIME FACTORS;

EID: 33644668963     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2005.11.065     Document Type: Article

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