Treatment with hydroxycarbamide for intermedia thalassaemia: Decrease of efficacy in some patients during long-term follow up [2]

British Journal of Haematology

Volumn 133, Issue 1, 2006, Pages 105-106

  Mancuso, Andrea ^a   Maggio, Aurelio ^a   Renda, Disma ^a   Di Marzo, Rosalba ^a   Rigano, Paolo ^a  

^a VILLA SOFIA CERVELLO HOSPITAL   (Italy)

Author keywords

Fetal hemoglobin; Hydroxycarbamide; Red cell disorders; Thalassaemia; Therapy

Indexed keywords

HEMOGLOBIN; HYDROXYUREA;

ADULT; BONE MARROW DEPRESSION; BONE MARROW TOXICITY; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; DRUG WITHDRAWAL; FOLLOW UP; GENOTYPE; HEMOGLOBIN BLOOD LEVEL; HUMAN; LETTER; PRIORITY JOURNAL; RETICULOCYTE; THALASSEMIA; TREATMENT OUTCOME; TREATMENT RESPONSE;

ADOLESCENT; ADULT; FOLLOW-UP STUDIES; HUMANS; HYDROXYUREA; MIDDLE AGED; NUCLEIC ACID SYNTHESIS INHIBITORS; THALASSEMIA; TIME FACTORS; TREATMENT FAILURE;

EID: 33644660100     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2006.06002.x     Document Type: Letter

References (6)

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2. Dixit A. Chatterjee T.C. Mishra P. Choudhry D.R. Mahapatra M. Tyagi S. Kabra M. Saxena R. Choudhry V.P. 2005 Hydroxyurea in thalassemia intermedia: a promising therapy Annals of Hematology 84 441 446
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4. Olivieri N.F. Rees D.C. Ginder G.D. Thein S.L. Brittenham G.M. Waje J.S. Wheatherall D.J. 1997 Treatment of thalassemia major with phenylbutyrate and hydroxyurea The Lancet 359 491 492
5. Rigano P. Manfre L. La Galla R. Renda D. Renda M.C. Calabresa A. Calzolari R. Maggio A. 1997 Clinical and hematological response to hydroxyurea in a patient with Hb Lepore/ß-thalassemia Hemoglobin 21 219 226
6. Singer S.T. Kuypers F.A. Olivieri N.F. Wheatherall D.J. Mignacca R. Coates T.D. Davies S. Sweeters N. Vichinsky E.P. 2005 Fetal hemoglobin augmentation in E/beta-thalassemia: clinical and haematological outcome British Journal of Haematology 131 378 388