Effect of efflux on telithromycin and macrolide susceptibility in Haemophilus influenzae

Antimicrobial Agents and Chemotherapy

Volumn 50, Issue 3, 2006, Pages 893-898

  Bogdanovich, Tatiana ^a   Bozdogan, Bülent ^b   Appelbaum, Peter C ^a  

^a PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^b ADNAN MENDERES UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; CARBONYL CYANIDE CHLOROPHENYLHYDRAZONE; CLARITHROMYCIN; KETOLIDE; MACROLIDE; RIBOSOME PROTEIN; RNA 23S; TELITHROMYCIN;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; GENE AMPLIFICATION; HAEMOPHILUS INFLUENZAE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RNA METHYLATION;

ANTI-BACTERIAL AGENTS; AZITHROMYCIN; CLARITHROMYCIN; DRUG RESISTANCE, MICROBIAL; HAEMOPHILUS INFECTIONS; HAEMOPHILUS INFLUENZAE; KETOLIDES; MACROLIDES; MICROBIAL SENSITIVITY TESTS; TIME FACTORS;

EID: 33644657837     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.50.3.893-898.2006     Document Type: Article

References (28)

1. Bartlett, J. G., R. F. Breiman, L. A. Mandell, T. M. File, and The Infectious Diseases Society of America. 1998. Community-acquired pneumonia in adults: guidelines for management. Clin. Infect. Dis. 26:811-838.
2. Beghi, G., F. Berni, L. Carratu, A. Casalini, G. Consigli, M. D'Anto, V. Gioia, A. Molino, G. Paizis, and A. Vaghi. 1995. Efficacy and tolerability of azithromycin versus amoxicillin/clavulanic acid in acute purulent exacerbation of chronic bronchitis. J. Chemother. 7:146-152.
3. Chodosh, S., A. Schreurs, G. Siami, H. W. Barkman, A. Anzueto, M. Shan, H. Moesker, T. Stack, S. Kowalsky, and The Bronchitis Study Group. 1998. Efficacy of oral ciprofloxacin versus clarithromycin for treatment of acute bacterial exacerbations of chronic bronchitis. Clin. Infect. Dis. 27:730-738.
4. Chollet, R., J. Chevalier, A. Bryskier, and J.-M. Pages. 2004. The AcrAB-TolC pump is involved in macrolide resistance but not in telithromycin efflux in Enterobacter aerogenes and Escherichia coli. Antimicrob. Agents Chemother. 48:3621-3624.
5. Dagan, R., E. Leibovitz, D. M. Fliss, A. Leiberman, M. R. Jacobs, W. Craig, and P. Yagupsky. 2000. Bacteriologic efficacies of oral azithromycin and oral cefaclor in treatment of acute otitis media in infants and young children. Antimicrob. Agents Chemother. 44:43-50.
6. Dagan, R., C. E. Johnson, S. McLinn, N. Abughali, J. Feris, E. Leibovitz, D. J. Burch, and M. R. Jacobs. 2000. Bacteriologic and clinical efficacy of amoxicillin/clavulanate versus azithromycin in acute otitis media. Pediatr. Infect. Dis. J. 19:95-104.
7. Doyle, P. W., and J. D. Woodham. 1991. Evaluation of the microbiology of chronic ethmoid sinusitis. J. Clin. Microbiol. 29:2396-2400.
8. Hansen, L. H., P. Mauvais, and S. Douthwaite. 1999. The macrolide-ketolide antibiotic binding site is formed by structures in domains II and V of 23S ribosomal RNA. Mol. Microbiol. 31:623-631.
9. Hickner, J. M., J. G. Bartlett, R. E. Besser, R. Gonzales, J. R. Hoffman, and M. A. Sande. 2001. Principles of appropriate antibiotic use for acute rhinosinusitis in adults: background. Ann. Intern. Med. 134:498-505.
10. Jacobs, M. R. 2001. Optimization of antimicrobial chemotherapy using pharmacokinetic and pharmacodynamic parameters. Clin. Microbiol. Infect. 7:589-596.
11. Leclercq, R. 2002. Mechanisms of resistance to macrolides and lincosamides: nature of the resistance elements and their clinical implications. Clin. Infect. Dis. 34:482-492.
12. Klein, J. O. 1994. Otitis media. Clin. Infect. Dis. 19:823-833.
13. Kobayashi, N., K. Nishino, and A. Yamaguchi. 2001. Novel macrolide-specific ABC-type efflux transporter in Escherichia coli. J. Bacteriol. 183:5639-5644.
14. Kosowska, K., K. Credito, G. A. Pankuch, D. B. Hoellman, G. Lin, C. Clark, B. Dewasse, P. McGhee, M. R. Jacobs, and P. C. Appelbaum. 2004. Activities of two novel macrolides, GW 773546 and GW 708408, compared with those of telithromycin, erythromycin, azithromycin, and clarithromycin against Haemophilus influenzae. Antimicrob. Agents Chemother. 48:4113-4119.
15. Mandell, L. A., T. J. Marrie, R. F. Grossman, A. W. Chow, R. H. Hyland, and The Canadian Community-Acquired Pneumonia Working Group. 2000. Canadian guidelines for the initial management of community-acquired pneumonia: an evidence-based update by the Canadian Infectious Diseases Society and the Canadian Thoracic Society. Clin. Infect. Dis. 31:383-421.
16. Mandell, L. A., J. G. Bartlett, S. F. Dowell, T. M. File, D. M. Musher, and C. Whitney. 2003. Update of practice guidelines for the management of community-acquired pneumonia in immunocompetent adults. Clin. Infect. Dis. 37:1405-1433.
17. Murphy, T. F. 2000. Haemophilus influenzae in chronic bronchitis. Semin. Respir. Infect. 15:41-51.
18. National Committee for Clinical Laboratory Standards. 2004. Standards for antimicrobial susceptibility testing, 13th informational supplement. NCCLS publication no. M100-S14. National Committee for Clinical Laboratory Standards, Wayne, Pa.
19. Niederman, M. S., L. A. Mandell, A. Anzueto, J. B. Bass, W. A. Broughton, G. D. Campbell, N. Dean, T. File, M. J. Fine, P. A. Gross, F. Martinez, T. J. Marrie, J. F. Plouffe, J. Ramirez, G. A. Sarosi, A. Torres, R. Wilson, and V. L. Yu. 2001. Guidelines for the management of adults with community-acquired pneumonia. Diagnosis, assessment of severity, antimicrobial therapy, and prevention. Am. J. Respir. Crit. Care Med. 163:1730.
20. Peric, M., B. Bozdogan, M. R. Jacobs, and P. C. Appelbaum. 2003. Effects of an efflux mechanism and ribosomal mutations on macrolide susceptibility of Haemophilus influenzae clinical isolates. Antimicrob. Agents Chemother. 47:1017-1022.
21. Peric, M., B. Bozdogan, C. Galderisi, D. Krissinger, T. Rager, and P. C. Appelbaum. 2004. Inability of L22 ribosomal protein alteration to increase macrolide MICs in the absence of efflux mechanism in Haemophilus influenzae HMC-S. J. Antimicrob. Chemother. 54:393-400.
22. Rello, J., R. Rodriguez, P. Jubert, B. Alvarez, and Study Group for Severe Community-Acquired Pneumonia. 1996. Severe community-acquired pneumonia in the elderly: epidemiology and prognosis. Clin. Infect. Dis. 23:723-728.
23. Sanchez, L., W. Pan, M. Vinas, and H. Nikaido. 1997. The acrAB homolog of Haemophilus influenzae codes for a functional multidrug efflux pump. J. Bacteriol. 179:6855-6857.
24. Shain, C. S., and G. W. Amsden. 2002. Telithromycin: the first of the ketolide. Ann. Pharmacother. 36:452-464.
25. Sutcliffe, J., T. Grebe, A. Tait-Kamradt, and L. Wondrack. 1996. Detection of erythromycin-resistant determinants by PCR. Antimicrob. Agents Chemother. 40:2562-2566.
26. Trepod, C., and J. E. Mott. 2004. Identification of the Haemophilus influenzae tolC gene by susceptibility profiles of insertionally inactivated efflux pump mutants. Antimicrob. Agents Chemother. 48:1416-1418.
27. Xiong, L., S. Shah, P. Mauvais, and A. S. Mankin. 1999. A ketolide resistance mutation in domain II of 23S rRNA reveals the proximity of hairpin 35 to the peptidyl transferase center. Mol. Microbiol. 31:633-639.
28. Zhanel, G. G., M. Dueck, D. J. Hoban, L. M. Vercaigne, J. M. Embil, A. S. Gin, and J. A. Karlowsky. 2001. Review of macrolides and ketolides: focuses on respiratory tract infections. Drugs 61:443-498.