Effects of Streptococcus mutans gtfC deficiency on mixed oral biofilms in vitro

Caries Research

Volumn 40, Issue 2, 2006, Pages 163-171

  Thurnheer, T ^a   Van Der Ploeg, J R ^a   Giertsen, E ^b   Guggenheim, B ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF BERGEN   (Norway)

Author keywords

Biofilm; Confocal laser scanning microscopy; Glucosyltransferases; Streptococcus mutans

Indexed keywords

GLUCAN; GLUCOSYLTRANSFERASE; GLUCOSYLTRANSFERASE C; HYDROXYAPATITE;

ARTICLE; BACTERIAL GENE; BIOFILM; BIOSYNTHESIS; CONFOCAL MICROSCOPY; DIFFUSION; ENZYMOLOGY; EXTRACELLULAR MATRIX; GENETICS; GROWTH, DEVELOPMENT AND AGING; MACROMOLECULE; METABOLISM; MICROBIOLOGY; PHYSIOLOGY; STREPTOCOCCUS MUTANS; TOOTH PLAQUE;

BIOFILMS; DENTAL PLAQUE; DIFFUSION; EXTRACELLULAR MATRIX; GENES, BACTERIAL; GLUCANS; GLUCOSYLTRANSFERASES; HYDROXYAPATITES; MACROMOLECULAR SUBSTANCES; MICROSCOPY, CONFOCAL; STREPTOCOCCUS MUTANS;

EID: 33644653892     PISSN: 00086568     EISSN: None     Source Type: Journal    
DOI: 10.1159/000091065     Document Type: Article

References (30)

1. Aoki H, Shiroza T, Hayakawa M, Sato S, Kuramitsu HK: Cloning of a Streptococcus mutans glucosyltransferase gene coding for insoluble glucan synthesis. Infect Immun 1986;53:587-594.
2. Banas JA, Vickerman MM: Glucan-binding proteins of the oral streptococci. Crit Rev Oral Biol Med 2003;14:89-99.
3. Bergeron LJ, Burne RA: Roles of fructosyltransferase and levanase-sucrase of Actinomyces naeslundii in fructan and sucrose metabolism. Infect Immun 2001;69:5395-5402.
4. Carlsson J: Regulation of sugar metabolism in relation to the feast-and-famine existence of plaque; in Guggenheim B (ed): Cariology Today. Basel, Karger, 1984, pp 205-211.
5. Costerton JW: Overview of microbial biofilms. J Ind Microbiol 1995;15:137-140.
6. Gmür R, Guggenheim B: Antigenic heterogeneity of Bacteroides intermedius as recognized by monoclonal antibodies. Infect Immun 1983;42:459-470.
7. Goodman SD, Gao Q: Characterization of the gtfB and gtfC promoters from Streptococcus mutans GS-5. Plasmid 2000;43:85-98.
8. Guggenheim B: Extracellular polysaccharides and microbial plaque. Int Dent J 1970;20:657-678.
9. Guggenheim B, Burckhardt JJ: Isolation and properties of a dextranase from Streptococcus mutans OMZ 176. Helv Odont Acta 1974;18:101-113.
10. Guggenheim B, Giertsen E, Schüpbach P, Shapiro S: Validation of an in vitro biofilm model of supragingival plaque. J Dent Res 2001a;80:363-370.
11. Guggenheim M, Shapiro S, Gmür R, Guggenheim B: Spatial arrangements and associative behavior of species in an in vitro oral biofilm model. Appl Environ Microbiol 2001b;67:1343-1350.
12. Hamada S, Slade HD: Biology, immunology, and cariogenicity of Streptococcus mutans. Microbiol Rev 1980;44:331-384.
13. Hanada N, Kuramitsu HK: Isolation and characterization of the Streptococcus mutans gtfC gene, coding for synthesis of both soluble and insoluble glucans. Infect Immun 1988;56:1999-2005.
14. Hanada N, Kuramitsu HK: Isolation and characterization of the Streptococcus mutans gtfD gene, coding for primer-dependent soluble glucan synthesis. Infect Immun 1989;57:2079-2085.
15. Hermanowicz SW: Biofilm structure: an interplay of models and experiments; in Wuertz S, Bishop PL, Wilderer PA (eds): Biofilms in Wastewater Treatment - An Interdisciplinary Approach. London, International Water Association Publishing, 2003, pp 32-47.
16. Loesche WJ: Role of Streptococcus mutans in human dental decay. Microbiol Rev 1986;50:353-380.
17. Marsh PD: Dental plaque; in Lappin-Scott HM, Costerton JW (eds): Microbial Biofilms. Cambridge, Cambridge University Press, 1995, pp 282-300.
18. McBain AJ, Bartolo RG, Catrenich CE, Charbonneau D, Ledder RG, Gilbert P: Growth and molecular characterization of dental plaque microcosms. J Appl Microbiol 2003;94:655-664.
19. Munro C, Michalek SM, Macrina FL: Cariogenicity of Streptococcus mutans V403 glucosyltransferase and fructosyltransferase mutants constructed by allelic exchange. Infect Immun 1991;59:2316-2323.
20. Podbielski A, Spellerberg B, Woischnik M, Pohl B, Lütticken R: Novel series of plasmid vectors for gene inactivation and expression analysis in group A streptococci (GAS). Gene 1996;177:137-147.
21. Rosan B, Hammond BF: Extracellular polysaccharides of Actinomyces viscosus. Infect Immun 1974;10:304-308.
22. Shapiro S, Giertsen E, Guggenheim B: An in vitro oral biofilm model for comparing the efficacy of antimicrobial mouthrinses. Caries Res 2002;36:93-100.
23. Sutherland IW: Biofilm exopolysaccharides; in Wingender J, Neu TR, Flemming HC (eds): Microbial Extracellular Polymeric Substances. Berlin, Springer, 1999, pp 73-92.
24. Thurnheer T, Gmür R, Shapiro S, Guggenheim B: Mass transport of macromolecules within an in vitro model of supragingival plaque. Appl Environ Microbiol 2003;69:1702-1709.
25. Tsumori H, Kuramitsu H: The role of the Streptococcus mutans glucosyltransferases in the sucrose-dependent attachment to smooth surfaces: essential role of the GtfC enzyme. Oral Microbiol Immunol 1997;12:274-280.
26. Ueda S, Kuramitsu HK: Molecular basis for the spontaneous generation of colonization-defective mutants of Streptococcus mutans. Mol Microbiol 1988;2:135-140.
27. van der Hoeven JS, Vogels GD, Bekkers MFJ: A levansucrase from Actinomyces viscosus. Caries Res 1976;10:33-48.
28. van der Ploeg JR, Guggenheim B: Deletion of gtfC of Streptococcus mutans has no influence on the composition of a mixed-species in vitro biofilm model of supragingival plaque. Eur J Oral Sci 2004;112:433-438.
29. Wimpenny J, Manz W, Szewzyk U: Heterogeneity in biofilms. FEMS Microbiol Rev 2000;24: 661-671.
30. Yamashita Y, Bowen WH, Burne RA, Kuramitsu HK: Role of the Streptococcus mutans gtf genes in caries induction in the specific-pathogen-free rat model. Infect Immun 1993;61:3811-3817.