Role of the media in vascular injury: Atherosclerosis and dissection

Toxicologic Pathology

Volumn 34, Issue 1, 2006, Pages 33-38

  Boor, Paul ^a   Yang, Yonzhen ^a   Gong, Bin ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Aorta; Atherosclerosis; Dissecting aortic aneurysm; Glutathione S transferase; Semicarbazide sensitive amine oxidase; Toxicology; Vascular media; Vascular smooth muscle cells

Indexed keywords

4 HYDROXYNONENAL; ALDEHYDE DERIVATIVE; AMINE OXIDASE (COPPER CONTAINING); ENZYME INHIBITOR; GLUTATHIONE TRANSFERASE; ISOENZYME; SEMICARBAZIDE; XENOBIOTIC AGENT;

ADOLESCENT; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA DISSECTING ANEURYSM; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BLOOD VESSEL; BLOOD VESSEL INJURY; CONTROLLED STUDY; CYTOPLASM; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIPID PEROXIDATION; MALE; METABOLISM; NEWBORN; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SMOOTH MUSCLE FIBER; THIRD TRIMESTER PREGNANCY; THORACIC AORTA; TUNICA MEDIA; UPREGULATION; UTERUS; VASCULAR SMOOTH MUSCLE;

ABNORMALITIES, DRUG-INDUCED; ADOLESCENT; ADULT; ANEURYSM, DISSECTING; ANIMALS; ANIMALS, NEWBORN; AORTA; AORTIC ANEURYSM; ATHEROSCLEROSIS; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; FEMALE; GLUTATHIONE TRANSFERASE; HUMANS; MALE; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; SEMICARBAZIDES; TUNICA MEDIA; UP-REGULATION;

ANIMALIA;

EID: 33644652658     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1080/01926230500369907     Document Type: Article

References (31)

1. Angouras, D., Sokolis, D. P., Dosios, T., Kostomitsopoulos, N., Boudoulas, H., Skalkeas, G., and Karayannacos, P. E. (2000). Effect of impaired vasa vasorum flow on the structure and mechanics of the thoracic aorta: implications for the pathogenesis of aortic dissection. Eur J Cardiothorac Surg 17, 468-73.
2. Boyle, J. R., McDermott, E., Crowther, M., Wills, A. D., Bell, P. R., and Thompson, M. M. (1998). Doxycycline inhibits elastin degradation and reduces metalloproteinase activity in a model of aneurysmal disease. J Vasc Surg 27, 354-61.
3. Brooke, B. S., Karnik, S. K., andLi, D. Y. (2003). Extracellular matrix in vascular morphogenesis and disease: structure versus signal. Trends Cell Biol 13, 51-6.
4. Camandola, S., Poli, G., and Mattson, M. P. (2000). The lipid peroxidation product 4-hydroxy-2,3-nonenal inhibits constitutive and inducible activity of nuclear factor kappa B in neurons. Brain Res Mol Brain Res 85, 53-60.
5. Cheng, J. Z., Singhal, S. S., Saini, M., Singhal, J., Piper, J. T., Van Kuijk, F. J., Zimniak, P., Awasthi, Y. C., and Awasthi, S. (1999). Effects of mGST A4 transfection on 4-hydroxynonenal-mediated apoptosis and differentiation of K562 human erythroleukemia cells. Arch Biochem Biophys 372, 29-36.
6. Choy, J. C., Granville, D. J., Hunt, D. W., and McManus, B. M. (2001). Endothelial cell apoptosis: biochemical characteristics and potential implications for atherosclerosis. J Mol Cell Cardiol 33, 1673-90.
7. Evangelista, A., Mukherjee, D., Mehta, R. H., O'Gara, P. T., Fattori, R., Cooper, J. V., Smith, D. E., Oh, J. K., Hutchison, S., Sechtem, U., Isselbacher, E. M., Nienaber, C. A., Pape, L. A., and Eagle, K. A. (2005). Acute intramural hematoma of the aorta: a mystery in evolution. Circulation 111, 1063-70.
8. Hagan, P. G., Nienaber, C. A., Isselbacher, E. M., Bruckman, D., Karavite, D. J., Russman, P. L., Evangelista, A., Fattori, R., Suzuki, T., Oh, J. K., Moore, A. G., Malouf, J. F., Pape, L. A., Gaca, C., Sechtem, U., Lenferink, S., Deutsch, H. J., Diedrichs, H., Marcos, y Robles, J., Llovet, A., Gilon, D., Das, S. K., Armstrong, W. F., Deeb, G. M., and Eagle, K. A. (2000). The International Registry of Acute Aortic Dissection (IRAD): new insights into an old disease. JAMA 283, 897-903.
9. Hayward, C., and Brock, D. J. (1997). Fibrillin-1 mutations in Marfan syndrome and other type-1 fibrillinopathies. Hum Mutat 10, 415-23.
10. He, N. G., Awasthi, S., Singhal, S. S., Trent, M. B., and Boor, P. J. (1998). The role of glutathione S-transferases as a defense against reactive electrophiles in the blood vessel wall. Toxicol Appl Pharmacol 152, 83-9.
11. He, N. G., Singhal, S. S., Chaubey, M., Awasthi, S., Zimniak, P., Partridge, C. A., and Awasthi, Y. C. (1996). Purification and characterization of a 4-hydroxynonenal metabolizing glutathione S-transferase isozyme from bovine pulmonary microvessel endothelial cells. Biochim Biophys Acta 1291, 182-8.
12. Helliker, K., and Burton, T. M. (2003). Medical Ignorance contributes to toll from aortic illness. Wall St J 11-6-2003., A12.
13. Ikonomidis, J. S., Gibson, W. C., Gardner, J., Sweterlitsch, S., Thompson, R. P., Mukherjee, R., and Spinale, F. G. (2003). A murine model of thoracic aortic aneurysms. J Surg Res 115, 157-63.
14. Januzzi, J. L., Isselbacher, E. M., Fattori, R., Cooper, J. V., Smith, D. E., Fang, J., Eagle, K. A., Mehta, R. H., Nienaber, C. A., and Pape, L. A. (2004). Characterizing the young patient with aortic dissection: results from the International Registry of Aortic Dissection (IRAD). J Am Coll Cardiol 43, 665-9.
15. Langford, S. D., Trent, M. B., Balakumaran, A., and Boor, P. J. (1999). Developmental vasculotoxicity associated with inhibition of semicarbazide- sensitive amine oxidase. Toxicol Appl Pharmacol 155, 237-44.
16. Manning, M. W., Cassi, L. A., Huang, J., Szilvassy, S. J., and Daugherty, A. (2002). Abdominal aortic aneurysms: fresh insights from a novel animal model of the disease. Vasc Med 7, 45-54.
17. Misra, P., Srivastava, S. K., Singhal, S. S., Awasthi, S., Awasthi, Y. C., and Boor, P. J. (1995). Glutathione S-transferase 8-8 is localized in smooth muscle cells of rat aorta and is induced in an experimental model of atherosclerosis. Toxicol Appl Pharmacol 133, 27-33.
18. Muller, B. T., Modlich, O., Prisack, H. B., Bojar, H., Schipke, J. D., Goecke, T., Feindt, P., Petzold, T., Gams, E., Muller, W., Hort, W., and Sandmann, W. (2002). Gene expression profiles in the acutely dissected human aorta. Eur J Vasc Endovasc Surg 24, 356-64.
19. Nelson, T. J., and Boor, P. J. (1982). Allylamine cardiotoxicity - IV. Metabolism to acrolein by cardiovascular tissues. Biochem Pharmacol 31, 509-514.
20. Nienaber, C. A., and Eagle, K. A. (2003). Aortic dissection: new frontiers in diagnosis and management: Part II: therapeutic management and follow-up. Circulation 108, 772-8.
21. Pepin, M., Schwarze, U., Superti-Furga, A., and Byers, P. H. (2000). Clinical and genetic features of Ehlers-Danlos syndrome type IV, the vascular type. N Engl J Med 342, 673-80.
22. Pereira, L., Andrikopoulos, K., Tian, J., Lee, S. Y., Keene, D. R., Ono, R., Reinhardt, D. P., Sakai, L. Y., Biery, N. J., Bunton, T., Dietz, H. C., and Ramirez, F. (1997). Targetting of the gene encoding fibrillin-1 recapitulates the vascular aspect of Marfan syndrome. Nat Genet 17, 218-22.
23. Sakalihasan, N., Limet, R., and Defawe, O. D. (2005). Abdominal aortic aneurysm. Lancet 365, 1577-89.
24. Sanduja, R., Ansari, G. A., and Boor, P. J. (1989). 3- Hydroxypropylmercapturic acid: a biologic marker of exposure to allylic and related compounds. J Appl Toxicol 9, 235-8.
25. Shi, W., Haberland, M. E., Jien, M. L., Shih, D. M., and Lusis, A. J. (2000). Endothelial responses to oxidized lipoproteins determine genetic susceptibility to atherosclerosis in mice. Circulation 102, 75-81.
26. Stehbens, W. E. (1999). Evaluation of aneurysm models, particularly of the aorta and cerebral arteries. Exp Mol Pathol 67, 1-14.
27. Stehblens, W. E., and Lie, J. T. (1995). Atherosclerosis and degenerative diseases of blood vessels. Vasc Pathol 1, 175-262.
28. Uchida, K. (1999). Current status of acrolein as a lipid peroxidation product. Trends Cardiovasc Med 9, 109-13.
29. Uchida, K. (2000). Cellular response to bioactive lipid peroxidation products. Free Radic Res 33, 731-7.
30. Yang, Y., Cheng, J. Z., Singhal, S. S., Saini, M., Pandya, U., Awasthi, S., and Awasthi, Y. C. (2001). Role of glutathione S-transferases in protection against lipid peroxidation. Overexpression of hGSTA2-2 in K562 cells protects against hydrogen peroxide-induced apoptosis and inhibits INK and caspase 3 activation. J Biol Chem 276, 19220-30.
31. Yang, Y., Sharma, R., Cheng, J. Z., Saini, M. K., Ansari, N. H., Andley, U. P., Awasthi, S., and Awasthi, Y. C. (2002). Protection of HLE B-3 cells against hydrogen peroxide- and naphthalene-induced lipid peroxidation and apoptosis by transfection with hGSTA1 and hGSTA2. Invest Ophthalmol Vis Sci 43, 434-45.