Death of neuronal clusters contributes to variance of age at onset in Huntington's disease

Neurogenetics

Volumn 7, Issue 1, 2006, Pages 21-25

  Čajavec, Branka ^a   Herzel, Hanspeter ^a   Bernard, Samuel ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Age of onset; Neuron death; One hit model; Polyglutamine repeat; Stochastic process

Indexed keywords

HUNTINGTIN; POLYGLUTAMINE;

BRAIN CORTEX; CELL LOSS; CORPUS STRIATUM; DEMENTIA; DISEASE SEVERITY; GENETIC VARIABILITY; HEREDITY; HUMAN; HUNTINGTON CHOREA; MORTALITY; MOTOR DYSFUNCTION; NERVE CELL NECROSIS; ONSET AGE; PATIENT; PRIORITY JOURNAL; PSYCHOLOGICAL ASPECT; REVIEW; STOCHASTIC MODEL; SYMPTOM;

ADULT; AGE OF ONSET; CELL DEATH; GENETIC VARIATION; HUMANS; HUNTINGTON DISEASE; MIDDLE AGED; MODELS, GENETIC; NEURONS; PEPTIDES; STOCHASTIC PROCESSES; TRINUCLEOTIDE REPEATS; VARIATION (GENETICS);

EID: 33644647341     PISSN: 13646745     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10048-005-0025-x     Document Type: Review

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