Assessment of anti-estrogenic activity of tamoxifen in transgenic mice expressing an enhanced green fluorescent protein gene regulated by estrogen response element

Biochimica et Biophysica Acta - General Subjects

Volumn 1760, Issue 2, 2006, Pages 164-171

  Hayashi, Yoshihiro ^a   Toda, Katsumi ^a   Saibara, Toshiji ^a   Okada, Teruhiko ^a   Enzan, Hideaki ^a  

^a KOCHI MEDICAL SCHOOL   (Japan)

Author keywords

Aromatase; EGFP; Estrogen; Knockout mouse; Tamoxifen

Indexed keywords

ANDROGEN; ANTIESTROGEN; AROMATASE; CLOMIFENE CITRATE; ENHANCED GREEN FLUORESCENT PROTEIN; EPIDERMAL GROWTH FACTOR; ESTRADIOL; FULVESTRANT; TAMOXIFEN CITRATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG ACTIVITY; DRUG EFFECT; ENZYME MECHANISM; ESTROGEN ACTIVITY; ESTROGEN RESPONSIVE ELEMENT; EVALUATION; FEMALE; GENE CONTROL; GENE FUNCTION; GENE INDUCTION; GENE TARGETING; HORMONE RESPONSE; IN VIVO STUDY; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE; UTERUS; UTERUS WEIGHT; WEIGHT GAIN;

ANIMALS; COMPLEMENT C3; COMPLEMENT FACTOR B; DIET; ESTRADIOL; ESTROGEN ANTAGONISTS; ESTROGENS; FEMALE; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; LACTOFERRIN; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; RESPONSE ELEMENTS; TAMOXIFEN; TESTIS; UTERUS;

ANIMALIA; MURINAE; MUS MUSCULUS;

EID: 33644631212     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagen.2005.08.016     Document Type: Article

References (34)

1. Early Breast Cancer Trialists' Collaborative Group Tamoxifen for early breast cancer: an overview of the randomised trials Lancet 351 1998 1451 1467
2. V.C. Jordan Tamoxifen: a personal retrospective Lancet Oncol. 1 2000 43 49
3. E. Senkus-Konefka, T. Konefka, and J. Jassem The effects of tamoxifen on the female genital tract Cancer Treat. Rev. 30 2004 291 301
4. M. Dutertre, and C.L. Smith Molecular mechanisms of selective estrogen receptor modulator (SERM) action J. Pharmacol. Exp. Ther. 295 2000 431 437
5. D.P. McDonnell The molecular pharmacology of SERMs Trends Endocrinol. Metab. 10 1999 301 311
6. F. Cosman, and R. Lindsay Selective estrogen receptor modulators: clinical spectrum Endocr. Rev. 20 1999 418 434
7. R.M. O'Regan, and V.C. Jordan The evolution of tamoxifen therapy in breast cancer: selective oestrogen-receptor modulators and downregulators Lancet Oncol. 3 2002 207 214
8. E.R. Simpson, M.S. Mahendroo, G.D. Means, M.W. Kilgore, M.M. Hinshelwood, S. Graham-Lorence, B. Amarneh, Y. Ito, C.R. Fisher, D. Michael, C.R. Mendelson, and S.E. Bulun Aromatase cytochrome P450, the enzyme responsible for estrogen biosynthesis Endocr. Rev. 15 1994 342 355
9. C.R. Fisher, K.H. Graves, A.F. Parlow, and E.R. Simpson Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the Cyp19 gene Proc. Nat. Acad. Sci. U. S. A. 95 1998 6965 6970
10. S. Honda, N. Harada, S. Ito, Y. Takagi, and S. Maeda Disruption of sexual behavior in male aromatase-deficient mice lacking exons 1 and 2 of the cyp 19 gene Biochem. Biophys. Res. Commun. 252 1998 445 449
11. K. Toda, K. Takeda, T. Okada, S. Akira, T. Saibara, T. Kaname, K. Yamamura, S. Onishi, and Y. Shizuta Targeted disruption of the aromatase P450 gene (Cyp19) in mice and their ovarian and uterine responses to 17β-oestradiol J. Endocrinol. 170 2001 99 111
12. K. Toda, Y. Okada, M. Zubair, K. Morohashi, T. Saibara, and T. Okada Aromatase-knockout mouse carrying an estrogen-inducible enhanced green fluorescent protein gene facilitates detection of estrogen actions in vivo Endocrinology 145 2004 1880 1888
13. K. Toda, Y. Hayashi, T. Okada, K. Morohashi, and T. Saibara Expression of the estrogen-inducible EGFP gene in aromatase-null mice reveals differential tissue-responses to estrogenic compounds Mol. Cell Endocrinol. 229 2005 119 126
14. D.B. Lubahn, J.S. Moyer, T.S. Golding, J.F. Couse, K.S. Korach, and O. Smithies Alternation of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene Proc. Natl. Acad. Sci. U. S. A. 90 1993 11162 11166
15. M. Koga, H. Tanaka, K. Yomogida, J. Tsuchida, K. Uchida, M. Kitamura, S. Sakoda, K. Matsumiya, A. Okuyama, and Y. Nishimune Expression of selenoprotein-P messenger ribonucleic acid in the rat testis Biol. Reprod. 58 1998 261 265
16. B.T. Akingbemi, R. Ge, C.S. Rosenfeld, L.G. Newton, D.O. Hardy, J.F. Catterall, D.B. Lubahn, K.S. Korach, and M.P. Hardy Estrogen receptor-alpha gene deficiency enhances androgen biosynthesis in the mouse Leydig cell Endocrinology 144 2003 84 93
17. J. Sambrook, and D.W. Russell Molecular Cloning: A Laboratory Manual 3rd ed. 2001 Cold Spring Harbor Laboratory Press New York 7.1 7.44
18. D.L. Buchanan, T. Setiawan, D.B. Lubahn, J.A. Taylor, T. Kurita, G.R. Cunha, and P.S. Cooke Tissue compartment-specific estrogen receptor-alpha participation in the mouse uterine epithelial secretory response Endocrinology 140 1999 484 491
19. S.H. Li, H.L. Huang, and Y.H. Chen Ovarian steroid-regulated synthesis and secretion of complement C3 and factor B in mouse endometrium during the natural estrous cycle and pregnancy period Biol. Reprod. 66 2002 322 332
20. H.L. Huang, S.T. Chu, and Y.H. Chen Ovarian steroids regulate 24p3 expression in mouse uterus during the natural estrous cycle and the preimplantation period J. Endocrinol. 162 1999 11 19
21. C. Richard, J. Gao, N. Brown, and J. Reese Aquaporin water channel genes are differentially expressed and regulated by ovarian steroids during the periimplantation period in the mouse Endocrinology 144 2003 1533 1541
22. Y.H. Liu, and C.T. Teng Characterization of estrogen-responsive mouse lactoferrin promoter J. Biol. Chem. 266 1991 21880 21885
23. A. Sourla, S. Luo, C. Labrie, A. Belanger, and F. Labrie Morphological changes induced by 6-month treatment of intact and ovariectomized mice with tamoxifen and the pure antiestrogen EM-800 Endocrinology 138 1997 5605 5617
24. P. Webb, G.N. Lopez, R.M. Uht, and P.J. Kushner Tamoxifen activation of the estrogen receptor/AP-1 pathway: potential origin for the cell-specific estrogen-like effects of antiestrogens Mol. Endocrinol. 9 1995 443 456
25. S. Green Modulation of oestrogen receptor activity by oestrogens and anti-oestrogens J. Steroid Biochem. Mol. Biol. 37 1990 747 751
26. P. Ciana, G. Di Luccio, S. Belcredito, G. Pollio, E. Vegeto, L.C. Tiveron, and A. Maggi Engineering of a mouse for the in vivo profiling of estrogen receptor activity Mol. Endocrinol. 15 2001 1104 1113
27. S.C. Nagel, J.L. Hagelbarger, and D.P. McDonell Development of an ER action indicator mouse for the study of estrogens, selective ER modulators (SERMs) and Xenobiotics Endocrinology 142 2001 4721 4728
28. J.G. Lemmen, R.J. Arends, A.L. van Boxtel, P.T. van der Saag, and B. van der Burg Tissue- and time-dependent estrogen receptor activation in estrogen reporter mice J. Mol. Endocrinol. 32 2004 689 701
29. A.M. Brzozowski, A.C. Pike, Z. Dauter, R.E. Hubbard, T. Bonn, O. Engstrom, L. Ohman, G.L. Greene, J.A. Gustafsson, and M. Carlquist Molecular basis of agonism and antagonism in the oestrogen receptor Nature 389 1997 753 758
30. N. Heldring, M. Nilsson, B. Buehrer, E. Treuter, and J.A. Gustafsson Identification of tamoxifen-induced coregulator interaction surfaces within the ligand-binding domain of estrogen receptors Mol. Cell. Biol. 24 2004 3445 3459
31. S. Nilsson, S. Makela, E. Treuter, M. Tujague, J. Thomsen, G. Andersson, E. Enmark, K. Pettersson, M. Warner, and J.A. Gustafsson Mechanisms of estrogen action Physiol. Rev. 81 2001 1535 1565
32. X.F. Liu, and M.K. Bagchi Recruitment of distinct chromatin-modifying complexes by tamoxifen-complexed estrogen receptor at natural target gene promoters in vivo J. Biol. Chem. 279 2004 15050 15058
33. S. Nilsson, S. Makela, E. Treuter, M. Tujague, J. Thomsen, G. Andersson, E. Enmark, K. Pettersson, M. Warner, and J.A. Gustafsson Mechanisms of estrogen action Physiol. Rev. 81 2001 1535 1565
34. Z. Weihua, S. Andersson, G. Cheng, E.R. Simpson, M. Warner, and J.A. Gustafsson Update on estrogen signaling FEBS Lett. 546 2003 17 24