Sex differences in vulnerability to drug self-administration

Experimental and Clinical Psychopharmacology

Volumn 14, Issue 1, 2006, Pages 34-41

  Lynch, Wendy J ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

Cocaine; Gender; Rats; Review; Self administration

Indexed keywords

SEX HORMONE;

ALCOHOLISM; CIRCADIAN RHYTHM; COCAINE DEPENDENCE; DRUG ABUSE; DRUG DEPENDENCE TREATMENT; DRUG INFUSION; DRUG SELF ADMINISTRATION; HUMAN; NONHUMAN; OVARY; REGULATORY MECHANISM; REINFORCEMENT; REVIEW; SEX DIFFERENCE; VULNERABLE POPULATION;

ESTROGENS; HUMANS; SELF ADMINISTRATION; SEX CHARACTERISTICS; SUBSTANCE-RELATED DISORDERS;

EID: 33644590674     PISSN: 10641297     EISSN: None     Source Type: Journal    
DOI: 10.1037/1064-1297.14.1.34     Document Type: Review

References (66)

1. Ahmed, S. H., & Koob, G. F. (1998, October 9). Transition from moderate to excessive drug intake: Change in hedonic set point. Science, 282, 298-300.
2. Ahmed, S. H., & Koob, G. F. (1999). Long-lasting increase in the set point for cocaine self-administration after escalation in rats. Psychopharmacology, 146, 303-312.
3. Anglin, M. D., Hser, Y. I., & McGlothlin, W. H. (1987). Sex differences in addict careers: 2. Becoming addicted. American Journal of Drug and Alcohol Abuse, 13, 59-71.
4. Arnold, J. M., & Roberts, D. C. (1997). A critique of fixed and progressive ratio schedules used to examine the neural substrates of drug reinforcement. Pharmacology, Biochemistry, and Behavior, 57, 441-447.
5. Becker, J. B. (1999). Gender differences in dopaminergic function in striatum and nucleus accumbens. Pharmacology, Biochemistry, and Behavior, 64, 803-812.
6. Blume, S. B. (1990). Chemical dependency in women: Important issues. American Journal of Drug and Alcohol Abuse, 16, 297-307.
7. Brady, K. T., & Randall, C. L. (1999). Gender differences in substance use disorders. Psychiatric Clinics of North America, 22, 241-252.
8. Brecht, M. L., O'Brien, A., von Mayrhauser, C., & Anglin, M. D. (2004). Methamphetamine use behaviors and gender differences. Addictive Behaviors, 29, 89-106.
9. Brown, P. L., & Jenkins, H. M. (1968). Auto-shaping of the pigeon's keg-peck. Journal of the Experimental Analysis of Behavior, 118, 1-8.
10. Caine, S. B., Bowen, C. A., Yu, G., Zuzga, D., Negus, S. S., & Mello, N. K. (2004). Effect of gonadectomy and gonadal hormone replacement on cocaine self-administration in female and male rats Neuropsychopharmacology, 29, 929-942.
11. Campbell, U. C., & Carroll, M. E. (2000). Acquisition of drug self-administration: Environmental and pharmacological interventions. Experimental and Clinical Psychopharmacology, 8, 312-325.
12. Campbell, U. C., Morgan, A. D., & Carroll, M. E. (2002). Sex differences in the effects of baclofen on the acquisition of intravenous cocaine self-administration in rats. Drug and Alcohol Dependence, 66, 61-69.
13. Carroll, M. E., & Lac, S. T. (1993). Autoshaping i.v. cocaine self-administration in rats: Effects of nondrug alternative reinforcers on acquisition. Psychopharmacology, 110, 5-12.
14. Carroll, M. E., Lynch, W. J., Roth, M. E., Morgan, A. D., & Cosgrove, K. P. (2004). Gender and hormones influence drug abuse. Trends in Pharmacological Sciences, 25, 273-279.
15. Carroll, M. E., Morgan, A. D., Lynch, W. J., Campbell, U. C., & Dess, N. K. (2002). I.V. cocaine and heroin self-administration in rats selectively bred for differential saccharin intake: Phenotype and sex differences. Pharmacology, Biochemistry, and Behavior, 161, 304-313.
16. Carroll, M. E., Roth, M. E., Voeller, R. K., & Nguyen, P. D. (2000). Acquisition of oral phencyclidine self-administration in rhesus monkeys: Effect of sex. Psychopharmacology, 149, 401-408.
17. Cicero, T. J., Aylward, S. C., & Meyer, E. R. (2003). Gender differences in the intravenous self-administration of mu opiate agonists. Pharmacology, Biochemistry, and Behavior, 74, 541-549.
18. Donny, E. C., Caggiula, A. R., Rowell, P. P., Gharib, M. A., Maldovan, V., Booth, S., et al. (2000). Nicotine self-administration in rats: Estrous cycle effects, sex differences and nicotinic receptor binding. Psychopharmacology, 151, 392-405.
19. Elman, I., Karlsgodt, K. H., & Gastfriend, D. R. (2001). Gender differences in cocaine craving among non-treatment-seeking individuals with cocaine dependence. American Journal of Drug and Alcohol Abuse, 27, 193-202.
20. Evans, S. M., Haney, M., & Foltin, R. W. (2002). The effects of smoked cocaine during the follicular and luteal phases of the menstrual cycle in women. Psychopharmacology, 159, 397-406.
21. Field, M., & Duka, T. (2004). Cue reactivity in smokers: The effects of perceived cigarette availability and gender. Pharmacology, Biochemistry, and Behavior, 78, 647-652.
22. Fitch, T. E., & Roberts, D. C. (1993). The effects of dose and access restrictions on the periodicity of cocaine self-administration in the rat. Drug and Alcohol Dependence, 33, 119-128.
23. Freeman, W. M., Brebner, K., Patel, K. M., Lynch, W. J., Roberts, D. C., & Vrana, K. E. (2002). Repeated cocain self-administration causes multiple changes on rat frontal cortex gene expression. Neurochemical Research, 27, 1181-1192.
24. Fuchs, R. A., Evans, K. A., Mehta, R. H., Case, J. M., & See, R. E. (2005). Influence of sex and estrous cyclicity on conditioned cue-induced reinstatement of cocaine-seeking behavior in rats. Psychopharmacology, 179, 662-672.
25. Griffin, M. L., Weiss, R. D., Mirin, S. M., & Lange, U. (1989). A comparison of male and female cocaine abusers. Archives of General Psychiatry, 46, 122-126.
26. Hernandez-Avila, C. A., Rounsaville, B. J., & Kranzler, H. R. (2004). Opioid-, cannabis- and alcohol-dependent women show more rapid progression to substance abuse treatment. Drug and Alcohol Dependence, 74, 265-272.
27. Hodgins, D. C., el-Guebaly, N., & Addington, J. (1997). Treatment of substance abusers: Single or mixed gender programs? Addiction, 92, 805-812.
28. Hser, Y. I., Anglin, M. D., & Booth, M. W. (1987). Sex differences in addict careers: 3. Addiction. American Journal of Drug and Alcohol Abuse, 13, 231-251.
29. Hu, M., Crombag, H. S., Robinson, T. E., & Becker, J. B. (2004). Biological basis of sex differences in the propensity to self-administer cocaine. Neuropsychopharmacology, 29, 81-85.
30. Jackson, L. R., & Becker, J. B. (2003). Progesterone suppresses the estradiol-induced enhancement of cocaine self-administration in female rats (Program No. 422.18.2003). Washington, DC: Society for Neuroscience.
31. Jackson, L. R., Robinson, T. E., & Becker, J. B. (2006). Sex differences and hormonal influences on acquisition of cocaine self-administration in rats. Neuropsychopharmacology.
32. Justice, A. J., & de Wit, H. (1999). Acute effects of d-amphetamine during the follicular and luteal phases of the menstrual cycle in women. Psychopharmacology, 145, 67-75.
33. Klein, L. C., Popke, E. J., & Grunberg, N. E. (1997). Sex differences in effects of predictable and unpredictable footshock on fentanyl self-administration in rats. Experimental and Clinical Psychopharmacology, 5, 99-106.
34. Kosten, T. R., Kosten, T. A., McDougle, C. J., Hameedi, F. A., McCance, E. F., Rosen, M. I., et al. (1996). Gender differences in response to intranasal cocaine administration to humans. Biological Psychiatry, 39, 147-148.
35. Lynch, W. J., Arrizi, M., & Carroll, M. E. (2000). Effects of sex and the estrous cycle on regulation of self-administered cocaine in rats. Psychopharmacology, 152, 132-139.
36. Lynch, W. J., & Carroll, M. E. (1999). Sex differences in the acquisition of intravenous cocaine and heroin self-administration in rats. Psychopharmacology, 144, 77-82.
37. Lynch, W. J., & Carroll, M. E. (2000). Reinstatement of cocaine self-administration in rats: Sex differences. Psychopharmacology, 148, 196-200.
38. Lynch, W. J., LaBounty, L. P., & Carroll, M. E. (1998). A novel paradigm to investigate regulation of drug intake in rats self-administering cocaine or heroin intravenously. Experimental and Clinical Psychopharmacology, 6, 22-31.
39. Lynch, W. J., Mangini, L., & Taylor, J. R. (2005). Neonatal isolation stress alters cocaine self-administration under extended access conditions and subsequent cue-induced relapse in male and female rats. Neuropsychopharmacology, 30, 322-329.
40. Lynch, W. J., & Roberts, D. C. S. (2004). The effect of cocaine self-administration on food-reinforced responding using a discrete trial procedure in rats. Neuropsychopharmacology, 29, 669-675.
41. Lynch, W. J., Roth, M. E., & Carroll, M. E. (2001). The role of estrogen in the acquisition of cocaine self-administration in female rats. Pharmacology, Biochemistry, and Behavior, 68, 641-646.
42. Lynch, W. J., Roth, M. E., & Carroll, M. E. (2002). Sex differences in drug abuse: Preclinical and clinical studies. Psychopharmacology, 164, 121-137.
43. Lynch, W. J., & Taylor, J. R. (2004). Sex differences in the behavioral effects of 24-hr access to cocaine under a discrete trial procedure. Neuropsychopharmacology, 29, 943-951.
44. Lynch, W. J., & Taylor, J. R. (2005). Decreased motivation to obtain cocaine following extended access: Effects of sex and estrogen. Neuropsychopharmacology, 30, 927-935.
45. McKay, J. R., Rutherford, M. J., Cacciola, J. S., Kabasakalian-McKay, R., & Alterman, A. I. (1996). Gender differences in the relapse experiences of cocaine patients. Journal of Nervous and Mental Disorders, 184, 616-622.
46. Mendelson, J. H., Sholar, M. B., Siegel, A. J., & Mello, N. K. (2001). Effects of cocaine on luteinizing hormone in women during the follicular and luteal phases of the menstrual cycle and in men. Journal of Pharmacology and Experimental Therapeutics, 296, 972-979.
47. Morgan, D., Brebner, K., Lynch, W. J., & Roberts, D. C. S. (2002). Increases in the reinforcing efficacy of cocaine after particular histories of reinforcement. Behavioral Pharmacology, 13, 389-396.
48. Niaura, R., Shadel, W. G., Abrams, D. B., Monti, P. M., Rohsenow, D. J., & Sirota, A. (1998). Individual differences in cue reactivity among smokers trying to quit: Effects of gender and cue type. Addictive Behaviors, 23, 209-224.
49. Nicolaides, B. M. (1996). The state's "sharp line between the sexes": Women, alcohol and the law in the United States, 1850-1980. Addiction, 91, 1211-1229.
50. Reed, B. G., & Mowbray, C. T. (1999). Mental illness and substance abuse: Implications for women's health and health care-access. Journal of the American Medical Women's Association, 54(2), 71-78.
51. Robbins, S. J., Ehrman, R. N., Childress, A. R., & O'Brien, C. P. (1999). Comparing levels of cocaine cue reactivity in male and female outpatients. Drug and Alcohol Dependence, 53, 223-230.
52. Roberts, D. C., Bennett, S. A., & Vickers, G. J. (1989). The estrous cycle affects cocaine self-administration on a progressive ratio schedule in rats. Psychopharmacology, 98, 408-411.
53. Roberts, D. C. S., Brebner, K., Vincler, M., & Lynch, W. J. (2002). Patterns of cocaine self-administration in rats produced by various access conditions under a discrete trials procedure. Drug and Alcohol Dependence, 67, 291-299.
54. Roth, M. E., & Carroll, M. E. (2004). Sex differences in the acquisition of IV methamphetamine self-administration and subsequent maintenance under a progressive ratio schedule in rats. Psychopharmacology, 172, 443-449.
55. Roth, M. E., Casimir, A. G., & Carroll, M. E. (2002). Influence of estrogen in the acquistion of intravenously self-administered heroin in female rats. Pharmacology, Biochemistry, and Behavior, 72, 313-318.
56. Roth, M. E., Cosgrove, K. P., & Carroll, M. E. (2004). Sex differences in the vulnerability to drug abuse: A review of preclinical studies. Neuroscience and Biobehavioral Reviews, 6, 533-546.
57. Rubin, A., Stout, R. L., & Longabaugh, R. (1996). Gender differences in relapse situations. Addiction, 91(Suppl.), S111-S120.
58. Sofuoglu, M., Babb, D. A., & Hatsukami, D. K. (2001). Progesterone treatment during the early follicular phase of the menstrual cycle: Effects on smoking behavior in women. Pharmacology, Biochemistry, and Behavior, 69, 299-304.
59. Sofuoglu, M., Babb, D. A., & Hatsukami, D. K. (2002). Effects of progesterone treatment on smoked cocaine response in women. Pharmacology, Biochemistry, and Behavior, 72, 431-435.
60. Sofuoglu, M., Dudish-Poulsen, S., Nelson, D., Pentel, P. R., & Hatsukami, D. K. (1999). Sex and menstrual cycle differences in the subjective effects from smoked cocaine in humans. Experimental and Clinical Psychopharmacology, 7, 274-283.
61. Sofuoglu, M., Mitchell, E., & Kosten, T. R. (2004). Effects of progesterone treatment on cocaine responses in male and female cocaine users. Pharmacology, Biochemistry, and Behavior, 78, 699-705.
62. Substance Abuse and Mental Health Services Administration (SAMHSA). (2004). Overview of findings from the 2003 National Survey on Drug Use and Health (Office of Applied Studies, NHSDA Series H-21, DHHS Publication No. SMA 03-3774). Rockville, MD: Author.
63. Tornatzky, W., & Miczek, K. A. (2000). Cocaine self-administration "binges": Transition from behavioral and autonomic regulation toward homeostatic dysregulation in rats. Psychopharmacology, 148, 289-298.
64. Van Etten, M. L., Neumark, Y. D., & Anthony, J. C. (1999). Male-female differences in the earliest stages of drug involvement. Addiction, 94, 1413-1419.
65. Westermeyer, J., & Boedicker, A. E. (2000). Course, severity, and treatment of substance abuse among women versus men. American Journal of Drug and Alcohol Abuse, 26, 523-535.
66. White, T. L., Justice, A. J., & de Wit, H. (2002). Differential subjective effects of D-amphetamine by gender, hormone levels and menstrual cycle phase. Pharmacology, Biochemistry, and Behavior, 73, 729-741.