Biological insights into the pathogenesis of cutaneous T-cell lymphomas (CTCL)

Seminars in Oncology

Volumn 33, Issue SUPPL. 3, 2006, Pages 3-6

  Whittaker, Sean ^a  

^a GUY'S AND ST THOMAS' NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD45RO ANTIGEN; CHEMOKINE RECEPTOR CCR4; COMPLEMENTARY DNA;

CANCER GRADING; CLONAL VARIATION; CUTANEOUS T CELL LYMPHOMA; DNA MICROARRAY; GENE EXPRESSION; HUMAN; MYCOSIS FUNGOIDES; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; REVIEW; SEZARY SYNDROME; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

EID: 33644555172     PISSN: 00937754     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.seminoncol.2005.12.015     Document Type: Article

References (20)

1. N. Yawalkar, K. Ferenczi, D.A. Jones Profound loss of T-cell receptor repertoire complexity in cutaneous T-cell lymphoma Blood 102 2003 4059 4066
2. C.L. Berger, R. Tigelaar, J. Cohen Cutaneous T cell lymphoma Malignant proliferation of T-regulatory cells Blood 15 2005 1640 1647
3. L. Karenko, M. Kahkonen, E.R. Hyytinen Notable losses at specific regions of chromosomes 10q and 13q in the Sezary syndrome detected by comparative genomic hybridization J Invest Dermatol 112 1999 392 395
4. L. Karenko, H. Nevala, M. Raatikainen Chromosomally clonal T cells in the skin, blood, or lymph nodes of two Sezary syndrome patients express CD45RA, CD45RO, CDw150, and interleukin-4, but no interleukin-2 or interferon-gamma J Invest Dermatol 116 2001 188 193
5. X. Mao, G. Orchard, D.M. Lillington Genetic alterations in primary cutaneous CD30+ anaplastic large cell lymphoma Genes Chromosomes Cancer 37 2003 176 185
6. L. Karenko, S. Hahtola, S. Paivinen Primary cutaneous T-cell lymphomas show a deletion or translocation affecting NAV3, the human virus homologue Cancer Res 65 2005 8101 8110
7. J.J. Scarisbrick, T.J. Mitchell, E. Calonje Microsatellite instability is associated with hypermethylation of the hMLH1 gene and reduced gene expression in mycosis fungoides J Invest Dermatol 121 2003 894 901
8. X. Mao, D.M. Lillington, J.J. Scarisbrick Molecular cytogenetic analysis of cutaneous T-cell lymphomas Identification of common genetic alterations in Sezary syndrome and mycosis fungoides Br J Dermatol 147 2002 464 475
9. T. Fischer, S. Gellrich, M. Muche Genomic aberrations and survival in cutaneous T-cell lymphomas J Invest Dermatol 122 2004 579 586
10. J.J. Scarisbrick, A.J. Woolford, R. Russell-Jones Allelotyping in mycosis fungoides and Sezary syndrome Common regions of allelic loss identified on 9p, 10q, and 17p J Invest Dermatol 117 2001 663 670
11. E.M. Wain, T.J. Mitchell, Russell Fine mapping of chromosome 10q deletions in mycosis fungoides and Sezary syndrome Identification of two discrete regions of deletion at 10q23.33-24.1 and 10q24.33-25.1 Genes Chromosomes Cancer 42 2005 184 192 ??
12. L. Kari, A. Loboda, M. Nebozhyn Classification and prediction of survival in patients with the leukemic phase of cutaneous T cell lymphoma J Exp Med 197 2003 1477 1488
13. M.W. Su, I. Dorocicz, W. Dragowska Aberrant expression of T-Plastin in Sezary cells Cancer Res 63 2003 7122 7127
14. R. van Doorn, R. Dijkman, M.H. Vermeer Aberrant expression of the tyrosine kinase receptor EphA4 and the transcription factor twist in Sezary syndrome identified by gene expression analysis Cancer Res 64 2004 5578 5586
15. L. Tracey, R. Villuendas, A.M. Dotor Mycosis fungoides shows concurrent deregulation of multiple genes involved in the TNF signaling pathway An expression profile study Blood 102 2003 1042 1050
16. X. Mao, G. Orchard, D.M. Lillington Amplification and overexpression of JUNB is associated with primary cutaneous T-cell lymphomas Blood 101 2003 1513 1519
17. H. Yu, R. Jove The STATS of cancer - New molecular targets come of age Nat Rev Cancer 4 2004 97 105
18. Q. Zhang, I. Nowak, E.C. Vonderheid Activation of Jak/STAT proteins involved in signal transduction pathway mediated by receptor for interleukin 2 in malignant T lymphocytes derived from cutaneous anaplastic large T-cell lymphoma and Sezary syndrome Proc Natl Acad Sci U S A 93 1996 9148 9153
19. L. Tracey, R. Villuendas, P. Ortiz Identification of genes involved in resistance to interferon-α in cutaneous T-cell lymphoma Am J Pathol 161 2002 1825 1837
20. T.J. Mitchell, S.J. Whittaker, S. John Dysregulated expression of COOH-terminally truncated Stat5 and loss of IL2-inducible Stat5-dependent gene expression in Sezary Syndrome Cancer Res 63 2003 9048 9054