Association of APOE e4 and cerebrovascular pathology in traumatic brain injury

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 77, Issue 3, 2006, Pages 363-366

  Smith, C ^a,b   Graham, D I ^b   Murray, L S ^b   Stewart, J ^b   Nicoll, J A R ^b,c  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E4;

ALLELE; APOE E4 GENE; ARTICLE; BRAIN CONTUSION; BRAIN DAMAGE; BRAIN ISCHEMIA; CEREBROVASCULAR DISEASE; DISEASE COURSE; DISEASE SEVERITY; FATALITY; GENE; GENETIC ASSOCIATION; GENOTYPE; HETEROZYGOTE; HIGH RISK POPULATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RISK FACTOR; TRAUMATIC BRAIN INJURY; UNITED KINGDOM;

EID: 33644554821     PISSN: 00223050     EISSN: None     Source Type: Journal    
DOI: 10.1136/jnnp.2005.074617     Document Type: Article

References (39)

1. Sorbi S, Nacmias N, Piacentini S, et al. ApoE as a prognostic factor for posttraumatic coma. Nat Med 1995;1:852.
2. Teasdale GM, Nicoll JA, Murray G, et al. Association of apolipoprotein E polymorphism with outcome after head injury. Lancet 1997;350:1069-71.
3. Alberts MJ, Graffagnino C, McClenny C, et al. ApoE genotype and survival from intracerebral haemorrhage. Lancet 1995;346:575.
4. McCarron MO, Hoffmann KL, DeLong DM, et al. Intracerebral hemorrhage outcome: apolipoprotein E genotype, hematoma, and edema volumes. Neurology 1999;53:2170-9.
5. Newman MF, Croughwell ND, Blumenthal JA, et al. Predictors of cognitive decline after cardiac operation. Ann Thorac Surg 1995;59:1326-30.
6. Tardiff BE, Newman MF, Saunders AM, et al. Preliminary report of a genetic basis for cognitive decline after cardiac operations. The Neurologic Outcome Research Group of the Duke Heart Center. Ann Thorac Surg 1997;64:715-20.
7. Schiefermeier M, Kollegger H, Madl C, et al. Apolipoprotein E polymorphism: survival and neurological outcome after cardiopulmonary resuscitation. Stroke 2000;31:2068-73.
8. Jordan BD, Relkin NR, Ravdin LD, et al. Apolipoprotein E epsilon4 associated with chronic traumatic brain injury in boxing. JAMA 1997;278:136-40.
9. Niskakangas T, Ohman J, Niemela M, et al. Association of apolipoprotein E polymorphism with outcome after aneurysmal subarachnoid hemorrhage: a preliminary study. Stroke 2001;32:1181-4.
10. Dunn LT, Stewart E, Murray GD, et al. The influence of apolipoprotein E genotype on outcome after spontaneous subarachnoid hemorrhage: a preliminary study. Stroke 2002;33:548-52.
11. Leung CH, Poon WS, Yu LM, et al. Apolipoprotein E genotype and outcome in aneurysmal subarachnoid hemorrhage. Stroke 2002;33:548-52.
12. McCarron MO, Muir KW, Nicoll JA, et al. Prospective study of apolipoprotein E genotype and functional outcome following ischemic stroke. Arch Neurol 2000;57:1480-4.
13. Horsburgh K, McCarron MO, White F, et al. The role of apolipoprotein E in Alzheimer's disease, acute brain injury and cerebrovascular disease: evidence of common mechanisms and utility of animal models. Neurobiol Aging 2000;21:245-55.
14. Roses AD, Einstein G, Gilbert J, et al. Morphological, biochemical, and genetic support for an apolipoprotein E effect on microtubular metabolism. Ann N Y Acad Sci 1990;777:146-57.
15. Lomnitski L, Kohen R, Chen Y, et al. Reduced levels of antioxidants in brains of apolipoprotein E-deficient mice following closed head injury. Pharmacol Biochem Behav 1997;56:669-73.
16. Tolar M, Keller JN, Chan S, et al. Truncated apolipoprotein E (ApoE) causes increased intracellular calcium and may mediate ApoE neurotoxicity. J Neurosci 1999;19:7100-10.
17. Hixson JE. Apolipoprotein E polymorphisms affect atherosclerosis in young males. Pathobiological Determinants of Atherosclerosis in Youth (PDAY) Research Group. Arterioscler Thromb 1991;11:1237-44.
18. Weir CJ, McCarron MO, Muir KW, et al. Apolipoprotein E genotype, coagulation, and survival following acute stroke. Neurology 2001;57:1097-100.
19. Graham DI, Gennarelli TA, McIntosh TK. Trauma. In: Graham DI, Lantos PL, eds. Greenfield's neuropathology, 7th ed. London: Arnold, 2002:823-98.
20. Nicoll JA, Burnett C, Love S, et al. High frequency of apolipoprotein E epsilon 2 allele in hemorrhage due to cerebral amyloid angiopathy. Ann Neurol 1997;41:716-21.
21. Adams JH, Doyle D, Ford I, et al. Diffuse axonal injury in head injury: definition, diagnosis and grading. Histopathology 1989;15:49-59.
22. Geddes JF, Whitwell HL, Graham DI. Traumatic axonal injury: practical issues for diagnosis in medicolegal cases. Neuropathol Appl Neurobiol 2000;26:105-16.
23. Graham DI, Ford I, Adams JH, et al. Ischaemic brain damage is still common in fatal non-missile head injury. J Neurol Neurosurg Psychiatry 1989;52:346-50.
24. Adams JH, Graham DI. The relationship between ventricular fluid pressure and the neuropathology of raised intracranial pressure. Neuropathol Appl Neurobiol 1976;2:323-32.
25. Adams JH, Graham DI, Scott G, et al. Brain damage in fatal non-missile head injury. J Clin Path 1980;33:1132-45.
26. Adams JH, Doyle D, Graham DI, et al. The contusion index: a reappraisal in human and experimental non-missile head injury. Neuropathol Appl Neurobiol 1985;11:299-308.
27. Graham DI, Lawrence AE, Adams JH, et al. Brain damage in fatal non-missile head injury without high intracranial pressure. J Clin Pathol 1988;41:34-7.
28. Jennett B, MacMillan R. Epidemiology of head injury. BMJ 1981;282:101-4.
29. Liaquat I, Dunn LT, Nicoll JA, et al. Effect of apolipoprotein E genotype on hematoma volume after trauma. J Neurosurg 2002;96:90-6.
30. McCarron MO, Weir CJ, Muir KW, et al. Effect of apolipoprotein E genotype on in-hospital mortality following intracerebral haemorrhage. Acta Neurol Scand 2003;107:106-9.
31. Shearer MJ. Vitamin K. Lancet 1995;345:229-34.
32. Giraud V, Naveau S, Betoulle D, et al. Influence of apolipoprotein E polymorphism in alcoholic cirrhosis. Gastroenterol Clin Biol 1998;22:571-5.
33. Leclercq PD, Murray LS, Smith C, et al. Cerebral amyloid angiopathy in traumatic brain injury: association with apolipoprotein E genotype. J Neurol Neurosurg Psychiatry 2005;76:229-33.
34. Laskowitz DT, Sheng H, Bart RD, et al. Apolipoprotein E-deficient mice have increased susceptibility to focal cerebral ischemia. J Cereb Blood Flow Metab 1997;17:753-8.
35. Horsburgh K, Kelly S, McCulloch J, et al. Increased neuronal damage in apolipoprotein E-deficient mice following global ischaemia. Neuroreport 1999;10:837-41.
36. Horsburgh K, McCulloch J, Nilsen M, et al. Intraventricular infusion of apolipoprotein E ameliorates acute neuronal damage after global cerebral ischemia in mice. J Cereb Blood Flow Metab 2000;20:458-62.
37. Horsburgh K, McCulloch J, Nilsen M, et al. Increased neuronal damage and apoE immunoreactivity in human apolipoprotein E, E4 isoform-specific, transgenic mice after global cerebral ischaemia. Eur J Neurosci 2000;12:4309-17.
38. Buttini M, Orth M, Bellosta S, et al. Expression of human apolipoprotein E3 or E4 in the brains of Apoe-/- mice: isoform-specific effects on neurodegeneration. J Neurosci 1999;19:4867-80.
39. Buttini M, Akeefe H, Lin C, et al. Dominant negative effects of apolipoprotein E4 revealed in transgenic models of neurodegenerative disease. Neuroscience 2000;97:207-10.