Antagonism by local anesthetics of sodium channel activators in the presence of scorpion toxins: Two mechanisms for competitive inhibition

Cellular and Molecular Neurobiology

Volumn 24, Issue 4, 2004, Pages 565-577

  Son, Stanley Lee ^a   Wong, Kin ^a   Strichartz, Gary ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Local anesthetic; Scorpion toxin; Sodium channels; Veratridine

Indexed keywords

LIDOCAINE; LOCAL ANESTHETIC AGENT; SCORPION VENOM; SODIUM CHANNEL; SODIUM CHANNEL AFFECTING AGENT; SODIUM CHANNEL BLOCKING AGENT; VERATRIDINE;

ALLOSTERISM; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; DRUG ANTAGONISM; NONHUMAN; PRIORITY JOURNAL; SCIATIC NERVE;

ANESTHETICS, LOCAL; ANIMALS; AXONS; BINDING SITES; BINDING, COMPETITIVE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; LIDOCAINE; MEMBRANE POTENTIALS; NEURAL CONDUCTION; NEURAL INHIBITION; RANA CATESBEIANA; SCIATIC NERVE; SCORPION VENOMS; SODIUM CHANNELS; VERATRIDINE;

ANIMALIA; ANURA; SCORPIONES;

EID: 3342966065     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:CEMN.0000023630.16308.54     Document Type: Article

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