Brain Na+,K+-ATPase isozyme activity and protein expression in ouabain-induced hypertension

Brain Research

Volumn 1018, Issue 2, 2004, Pages 171-180

  Kent, Mary Anne H ^a   Huang, Bing S ^a   Van Huysse, James W ^a   Leenen, Frans H H ^a  

^a UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

Author keywords

Brain; Cardiovascular regulation; Digibind; Endocrine and autonomic regulation; Na+,K+ ATPase subunit expression; Na+,K+ ATPase activity; Ouabain induced hypertension

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); BRAIN ENZYME; IMMUNOGLOBULIN F(AB) FRAGMENT; ISOENZYME; OUABAIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BRAIN CORTEX; CONTROLLED STUDY; ENZYME ACTIVITY; HYPERTENSION; HYPOTHALAMUS; MALE; MEAN ARTERIAL PRESSURE; MEDULLA OBLONGATA; MICROSOME; NONHUMAN; PONS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; BLOOD PRESSURE; CEREBRAL CORTEX; DOWN-REGULATION; ENZYME INHIBITORS; HYPERTENSION; HYPOTHALAMUS; IMMUNOGLOBULIN FAB FRAGMENTS; INJECTIONS, INTRAVENTRICULAR; INJECTIONS, SUBCUTANEOUS; ISOENZYMES; MALE; MEDULLA OBLONGATA; MICROSOMES; NA(+)-K(+)-EXCHANGING ATPASE; OUABAIN; PONS; RATS; RATS, WISTAR;

EID: 3342938275     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2004.05.059     Document Type: Article

References (40)

1. +-ATPase activity in Dahl salt-sensitive versus resistant rats. J. Hypertens. 13:1995;517-522
2. +. Am. J. Physiol. 279:2000;H679-H691
3. Arystarkhova E., Sweadner K.J. Isoform-specific monoclonal antibodies to Na,K-ATPase alpha subunits. Evidence for a tissue-specific post-translational modification of the alpha subunit. J. Biol. Chem. 271:1996;23407-23417
4. +-ATPase in erythrocytes. J. Hypertens. 9:1991;S304-S305
5. +-ATPase: heterogeneity in structure, diversity in function. Am. J. Physiol. 275:1998;F633-F650
6. Blasi J.M.V., Cena V., Gonzalez-Garcia C., Marsal J., Solsona C. Ouabain induces acetylcholine release from pure cholinergic synaptosomes independently of extracellular calcium concentrations. Neurochem. Res. 13:1998;1035-1041
7. 2+ stores and cell responsiveness. Am. J. Physiol. 264:1993;C1367-C1387
8. Budzikowski A.S., Leenen F.H.H. Brain ouabain in the median preoptic nucleus mediates salt-sensitive hypertension in spontaneously hypertensive rats. Hypertension. 29:1997;599-605
9. +-ATPase α and β subunits. Mol. Brain Res. 21:1994;333-343
10. 3H-ouabain binding sites in various tissues of spontaneously hypertensive rats. Eur. J. Pharmacol. 122:1986;311-319
11. +-ATPase. Biochim. Biophys. Acta. 481:1977;648-659
12. +-ATPase isoform expression and enzymatic activity after aortic constriction. Brain Res. 944:2002;124-134
13. Gao J., Wymore R.S., Wang Y., Gaudette G.R., Krukenkamp I.B., Cohen I.S., Mathias R.T. Isoform-specific stimulation of cardiac Na/K pumps by nanomolar concentrations of glycosides. J. Gen. Physiol. 119:2002;297-312
14. 3H-DOPA in various regions of the brain. J. Neurochem. 13:1996;655-669
15. +-ATPase in cultured astrocytes. J. Neurochem. 69:1997;2189-2196
16. Huang B.S., Huang X., Harmsen E., Leenen F.H. Chronic central versus peripheral ouabain, blood pressure and sympathetic activity in rats. Hypertension. 23:1994;1087-1090
17. Jones D.L., Lo S. Ouabain injected into the hypothalamus elicits pressor responses in anaesthetized rats. A mapping study. Pharmacol. Biochem. Behav. 36:1990;979-983
18. + pump low and high ouabain affinity α subunit isoforms are differently distributed in cells. Proc. Natl. Acad. Sci. U. S. A. 94:1997;1800-1805
19. Manunta P., Rogowski A.C., Hamilton B.P., Hamlyn J.M. Ouabain-induced hypertension in the rat: relationships among plasma and tissue ouabain and blood pressure. J. Hypertens. 12:1994;549-560
20. +-ATPase activity and acetylcholine release in rat cortical synaptosomes. J. Neurochem. 36:1981;467-475
21. +-ATPase isozyme diversity; comparative biochemistry and physiological implications of novel functional interactions. Biosci. Rep. 20:2000;51-91
22. O'Brien J.W., Lingrel L.B., Wallick E.T. Ouabain binding kinetics of the rat alpha two and alpha three isoforms of the sodium-potassium adenosine triphosphate. Arch. Biochem. Biophys. 310:1994;32-39
23. Pacholczyk T., Sweadner K.J. Epitope and mimotope for an antibody to the Na,K-ATPase. Protein Sci. 6:1997;1537-1548
24. +-ATPase as an effector of synaptic transmission. Neurochem. Int. 20:1992;19-22
25. Rodriguez-Manas L., Sanchez-Ferrer C.F., Pareja A., Casado M.A., Arribas S., Salaices M., Marin J. Neurogenic component of ouabain-evoked contractions is modulated by endothelium. Hypertension. 23:1994;10-17
26. +-ATPase in ouabain-induced hypertension. Br. J. Pharmacol. 135:2002;771-781
27. +-ATPase. Am. J. Physiol. 266:1994;H350-H353
28. + and ouabain in rat synaptosomes. Neurosci. Lett. 107:1989;284-288
29. +)-ATPase activity in different rat brain regions. Experientia. 36:1980;1348-1350
30. Sweadner K.J. Ouabain-evoked norepinephrine release from intact rat sympathetic neurons: evidence for carrier mediated release. J. Neurosci. 5:1985;2397-2406
31. +-ATPase. Biochim. Biophys. Acta. 988:1989;185-220
32. +-ATPase isozymes in neurons and glia. Can. J. Physiol. Pharm. 70:1992;S255-S259
33. Teruya H., Yamazato M., Muratani H., Sakima A., Takishita S., Terano Y., Fukiyama K. Role of ouabain-like-compound in the rostral ventral medulla in rats. J. Clin. Invest. 99:1997;2791-2798
34. +-ATPase. J. Biol. Chem. 271:1996;7104-7112
35. Veerasingham S.J., Leenen F.H. Ouabain and central sodium induced hypertension depend on the ventral anteroventral third ventricle region. Am. J. Physiol. 276:1999;H63-H70
36. +-activated adenosinetriphosphatase as a trigger in neurotransmitter release. Neuroscience. 3:1978;367-384
37. +-ATPase, its endogenous ligands and neurotransmitter release. Neurochem. Int. 20:1992;11-17
38. 14C]acetylcholine and other substances from synaptosomes. J. Neurochem. 37:1981;1467-1474
39. Vasallo D.V, Songu-Mize E., Rossoni L.V., Amaral S.M. Effects of ouabain on vascular reactivity. Braz. J. Med. Biol. 30:1997;545-552
40. Wang H., Yuan W.Q., Lu Z.R. Differential regulation of the sodium pump alpha-subunit isoform gene by ouabain and digoxin in tissues of rats. Hypertens. Res. 23:2000;S55-S60. Suppl.