Injection of orexin a into the diagonal band of Broca induces symphatetic and hyperthermic reactions

Brain Research

Volumn 1018, Issue 2, 2004, Pages 265-271

  Monda, M ^a   Viggiano, An ^a   Viggiano, Al ^a   Fuccio, F ^a   De Luca, V ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

Diagonal band of Broca; Orexin A; Rat; Sympathetic activity; Thermogenesis

Indexed keywords

GLYCEROL; OREXIN A; SODIUM CHLORIDE; URETHAN;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; BROWN ADIPOSE TISSUE; COLON; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIAGONAL BAND OF BROCA; HEART RATE; HYPERTHERMIA; INJECTION; LUMBAR SPINE; MALE; MONITORING; NERVE CONDUCTION; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN; SYMPATHETIC NERVE; SYMPATHETIC TONE; TEMPERATURE; WHITE ADIPOSE TISSUE;

ACTION POTENTIALS; ADIPOSE TISSUE; ANALYSIS OF VARIANCE; ANIMALS; CARRIER PROTEINS; DIAGONAL BAND OF BROCA; DOSE-RESPONSE RELATIONSHIP, DRUG; FEVER; GLYCEROL; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICROINJECTIONS; NEUROPEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; SYMPATHETIC NERVOUS SYSTEM; THERMOGENESIS;

EID: 3342922483     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2004.05.084     Document Type: Article

References (38)

1. Beuckmann C.T., Yanagisawa M. Orexins: from neuropeptides to energy homeostasis and sleep/wake regulation. J. Mol. Med. 80:2002;329-342
2. Cannon B.J., Houstek J., Nedergaard J. Brown adipose tissue. More than an effector of thermogenesis. Ann. N.Y. Acad. Sci. 856:1998;171-187
3. Cullinan W.E., Zaborsky L. Organization of ascending hypothalamic projections to the rostral forebrain with special reference to the innervation of cholinergic projection neurons. J. Comp. Neurol. 306:1991;631-667
4. Dark J., Miller D.R., Lewis D.A., Fried S.K., Bunkin D. Noradrenaline-induced lipolysis in adipose tissue is suppressed at hibernation temperatures in groud squirrels. J. Neuroendocrinol. 15:2003;451-458
5. De Lecea L., Kilduff T.S., Peyron C., Gao X.B., Foye P.E., Danielson P.E., Fukuhara C., Battenberg E.L.F., Gautvik V.T., Bartlett F.S. II, Frankel W.N., Van Den Pol A.N., Bloom F.E., Gautvik K.M., Sutcliffe J.G. The hypocretins: two hypothalamic peptides with neuroexcitatory activity. Proc. Natl. Acad. Sci. U. S. A. 95:1998;322-327
6. De Luca B., Monda M., Pellicano M.P., Zenga A. Cortical control of thermogenesis induced by lateral hypothalamic lesion and overeating. Am. J. Physiol. 253:1987;R626-R633
7. Dodt C., Lonnroth P., Wellhoner J.P., Fehm H.L., Elam M. Sympathetic control of white adipose tissue in lean and obese humans. Acta Physiol. Scand. 177:2003;351-357
8. Dolnikoff M., Martin-Hidalgo A., Machado U.F., Lima F.B., Herrera E. Decreased lipolysis and enhanced glycerol and glucose utilization by adipose tissue prior to development of obesity in monosodium glutamate (MSG) treated-rats. Int. J. Obes. Relat. Metab. Disord. 25:2001;426-433
9. Galas L., Vaudry H., Braun B., Van Den Pol A.N., De Lecea L., Sutcliffe J.G., Chartrel N. Immunohistochemical localization and biochemical characterization of hypocretin/orexin-related peptides in the central nervous system of the frog Rana ridibunda. J. Comp. Neurol. 429:2001;242-252
10. Goubillon M.L., Caraty A., Herbison A.E. Evidence in favour of a direct input from the ventromedial nucleus to gonadotropin-releasing hormone neurones in the ewe: an anterograde tracing study. J. Neuroendocrinol. 14:2002;95-100
11. Halvorson I., Gregor L., Thornhill J.A. Brown adipose tissue thermogenesis is activated by electrical and chemical (L-glutamate) stimulation of the ventromedial hypothalamic nucleus in cold acclimated rats. Brain Res. 552:1990;76-82
12. Haynes A.C., Chapman H., Taylor C., Moore G.B., Cawthorne M.A., Tadayyon M., Clapham J.C., Arch J.R. Anorectic, thermogenic and anti-obesity activity of a selective orexin-1 receptor antagonist in ob/ob mice. Regul. Pept. 104:2002;153-159
13. Herrera E., Amusquivar E., Cacho J. Changes in dietary fatty acids modify the decreased lipolytic beta3-adrenergic response to hyperinsulinemia in adipocytes from pregnant and non pregnant rats. Metabolism. 49:2000;1180-1187
14. A. Lubkin, A. Stricker-Krongrad, Independent feeding and metabolic action of orexins in mice, Biochem. Biophys. Res. Commun. 253, 241-245
15. Marcus J.N., Aschkenasi C.J., Lee C.E., Chemelli R.M., Saper C.B., Yanagisawa M., Elmquist J.K. Differential expression of orexin receptors 1 and 2 in the rat brain. J. Comp. Neurol. 435:2001;6-25
16. Monda M., Amaro S., Sullo A., De Luca B. Posterior hypothalamic activity and cortical control during the PGE1 hypertermia. NeuroReport. 6:1994;135-139
17. Monda M., Sullo A., De Luca B. Lesions of ventromedial hypothalamus reduce post-ingestional thermogenesis. Physiol. Behav. 61:1997;687-691
18. Monda M., Viggiano A., Mondola P., De Luca V. Inhibition of prostaglandin synthesis reduces hyperthermic reactions induced by hypocretin-1/orexin A. Brain Res. 909:2001;68-74
19. Monda M., Viggiano A., De Luca V. A paradoxical effect of orexin a: the hypophagia induced by hyperthermia. Brain Res. 961:2003;220-228
20. Monda M., Viggiano A., De Luca V. Haloperidol reduces the sympathetic and thermogenic activation induced by orexin A. Neurosci. Res. 45:2003;17-23
21. Morrison S.F. Differential control of sympathetic outflow. Am. J. Physiol. 281:2001;R683-R698
22. Oka K., Oka T., Hori T. Prostaglandin E2 may induce hyperthermia through EP1 receptor in the anterior wall of the third ventricle and neighboring preoptic regions. Brain Res. 767:1997;92-99
23. Oldfield B.J., Giles M.E., Watson A., Anderson C., Colvill L.M., McKinley M.J. The neurochemical characterisation of hypothalamic pathways projecting polysynaptically to brown adipose tissue in the rat. Neuroscience. 110:2002;515-526
24. Pellegrino L.J., Pellegrino A.S., Cushman A.J. A Stereotaxic Atlas of the Rat Brain. 1979;Plenum Press, New York
25. Ramos M.P., Crespo-Solans M.D., del Campo S., Cacho J., Herrera E. Fat accumulation in the rat during early pregnancy is modulated by enhanced insulin responsiveness. Am. J. Physiol. 285:2003;E318-E328
26. Rayner D.V. The sympathetic nervous system in white adipose tissue regulation. Proc. Nutr. Soc. 60:2001;357-364
27. Sakurai T., Amemiya A., Ishii M., Matsuzaki I., Chemelli R.M., Tanara H., Williams S.C., Richardson J.A., Kozlowski G.P., Wilson S., Arch J.R.S., Buckingham R.E., Haynes A.C., Carr S.A., Annan R.S., McNulty D.E., Liu W.S., Terrett J.A., Elshourbary N.A., Bergsma D.J., Yanagisawa M. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell. 92:1998;573-585
28. Semba K. Multiple output pathways of the basal forebrain: organization, chemical heterogeneity, and roles in vigilance. Behav. Brain Res. 115:2000;117-141
29. Shirasaka T., Nakazato M., Matsukura S., Takasaki M., Kannan H. Sympathetic and cardiovascular actions of orexins in conscious rats. Am. J. Physiol. 277:1999;R1780-R1785
30. Sweet D.C., Levine A.S., Billington C.J., Kotz C.M. Feeding response to central orexins. Brain Res. 821:1999;535-538
31. Taheri S., Zeitzer J.M., Mignot E. The role of hypocretins (orexins) in sleep regulation and narcolepsy. Annu. Rev. Neurosci. 25:2002;283-313
32. Tavares R.F. Pressor effects of L-glutamate injected into the diagonal band of Broca of unanesthetized rats. Brain Res. 959:2003;312-319
33. Thornhill J.A., Halvorson I. Electrical stimulation of the posterior and ventromedial hypothalamic nuclei causes specific activation of shivering and nonshivering thermogenesis. Can. J. Physiol. Pharm. 72:1994;89-96
34. Trivedi P., Yu H., MacNeil D.J., Van der Ploeg L.H., Guan X.M. Distribution of orexin receptor mRNA in the rat brain. FEBS Lett. 438:1998;71-75
35. Wolf G. Orexins: a newly discovered family of hypothalamic regulators of food intake. Nutr. Rev. 56:1998;172-173
36. Wu M., Zaborsky L., Hajszan T., van den Pol A.N., Alreja M. Hypocretin/orexin innervation and excitation of identified septohippocampal cholinergic neurons. J. Neurosci. 24:2004;3527-3536
37. Yoshimichi G., Yoshimatsu H., Masaki T., Sakata T. Orexin-A regulates body temperature in coordination with arousal status. Exp. Biol. Med. 226:2001;468-476
38. Yoshimoto Y., Sakai K., Luppi P.H., Fort P., Salvert D., Jouvet M. Forebrain afferents to the cat posterior hypothalamus: a double labeling study. Brain Res. Bull. 23:1989;83-104