Murine metanephric mesenchyme possesses characteristics of vascular endothelial cells in vitro

Nephron - Experimental Nephrology

Volumn 102, Issue 3-4, 2006, Pages

  Usui, Joichi ^a   Yamada, Risa ^a   Kanemoto, Katsuyoshi ^a   Koyama, Akio ^a   Nagata, Michio ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Cell lines; Metanephric mesenchyme; Vascular endothelial cell; VE cadherin; vWF

Indexed keywords

ANGIOPOIETIN RECEPTOR; ANTIBODY; BASIC FIBROBLAST GROWTH FACTOR; CD31 ANTIGEN; CELL MARKER; LOW DENSITY LIPOPROTEIN; MESSENGER RNA; PODOCALYXIN; VASCULAR ENDOTHELIAL CADHERIN; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; VON WILLEBRAND FACTOR;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL FATE; CELL LINE; CELL MATURATION; CELL STIMULATION; CONTROLLED STUDY; ENDOTHELIUM CELL; HYPOXIA; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE; IN VITRO STUDY; KIDNEY BLOOD VESSEL; MESENCHYME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VASCULAR ENDOTHELIUM;

ANIMALS; BIOLOGICAL MARKERS; CADHERINS; CELL DIFFERENTIATION; CELL LINE, TRANSFORMED; CYTOPLASMIC GRANULES; ENDOTHELIAL CELLS; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOHISTOCHEMISTRY; KIDNEY; MESODERM; MICE; PHENOTYPE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; VON WILLEBRAND FACTOR;

EID: 33344472839     PISSN: 16602129     EISSN: None     Source Type: Journal    
DOI: 10.1159/000089687     Document Type: Article

References (22)

1. Saxén L: Organogenesis of the Kidney. Cambridge, Cambridge University Press, 1987, pp 129-142.
2. Osathanondh V, Potter EL: Development of human kidney as shown by microdissection. V. Development of vascular pattern of glomerulus. Arch Pathol 1966;82:403-411.
3. Ekblom P, Sariola H, Karkinen-Jääskeläinen M, Saxén L: The origin of the glomerular endothelium. Cell Differ 1982;11:35-39.
4. Abrahamson DR, Robert B, Hyink DP, St John PL, Daniel TO: Origins and formation of microvasculature in the developing kidney. Kidney Int 1998;54(suppl):S7-11.
5. Sariola H, Ekblom P, Lehtonen E, Saxén L: Differentiation and vascularization of the metanephric kidney grafted on the chorioallantoic membrane. Dev Biol 1983;96:427-435.
6. Hyink DP, Tucker DC, St John PL, Leardkamolkarn V, Accavitti MA, Abrass CK, Abrahamson DR: Endogenous origin of glomerular endothelial and mesangial cells in grafts of embryonic kidneys. Am J Physiol 1996;270:F886-899.
7. Robert B, St John PL, Hyink DP, Abrahamson DR: Evidence that embryonic kidney cells expressing flk-1 are intrinsic, vasculogenic angioblasts. Am J Physiol 1996;271:F744-753.
8. Tufro-McReddie A, Norwood VF, Aylor KW, Botkin SJ, Carey RM, Gomez RA: Oxygen regulates vascular endothelial growth factor-mediated vasculogenesis and tubulogenesis. Dev Biol 1997;183:139-149.
9. Loughna S, Hardman P, Landels E, Jussila L, Alitalo K, Woolf AS: A molecular and genetic analysis of renal glomerular capillary development. Angiogenesis 1997;1:84-101.
10. Takemura T, Hino S, Kuwajima H, Yanagida H, Okada M, Nagata M, Sasaki S, Barasch J, Harris RC, Yoshioka K: Induction of collecting duct morphogenesis in vitro by heparin-binding epidermal growth factor-like growth factor. J Am Soc Nephrol 2001;12:964-972.
11. Oliver JA, Barasch J, Yang J, Herzlinger D, Al-Awqati Q: Metanephric mesenchyme contains embryonic renal stem cell. Am J Physiol 2002;283:F799-809.
12. Hara T, Nakano Y, Tanaka M, Tamura K, Sekiguchi T, Minehata K, Copeland NG, Jenkins NA, Okabe M, Kogo H, Mukouyama Y, Miyajima A: Identification of podocalyxin-like protein 1 as a novel cell surface marker for hemangioblasts in the murine aorta-gonad-mesonephros region. Immunity 1999;11:567-578.
13. Kitamoto Y, Tokunaga H, Tomita K: Vascular endothelial growth factor is an essential molecule for mouse kidney development: glomerulogenesis and nephrogenesis. J Clin Invest 1997;99:2351-2357.
14. Tufro A, Norwood VF, Carey RM, Gomez RA: Vascular endothelial growth factor induces nephrogenesis and vasculogenesis. J Am Soc Nephrol 1999;10:2125-2134.
15. Denis C, Methia N, Frenette PS, Rayburn H, Ullman-Culleré M, Hynes RO, Wagner DD: A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis. Proc Natl Acad Sci USA 1998;95:9524-9529.
16. Lloyd RV, Erickson LA, Jin L, Kulig E, Qian X, Cheville JC, Scheithauer BW: p27kip1: A multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers. Am J Pathol 1999;154:313-323.
17. Reichert M, Eick D: Analysis of cell cycle arrest in adipocyte differentiation. Oncogene 1999;18:459-466.
18. Loughna S, Yuan H-T, Woolf AS: Effects of oxygen on vascular patterning in Tiel/LacZ metanephric kidneys in vitro. Biochem Biophys Res Commun 1998;247:361-366.
19. Nishikawa SI, Nishikawa S, Hiroshima M, Matsuyoshi N, Kodama H: Progressive lineage analysis by cell sorting and culture identifies FLK1+VE-cadherin+ cells at a diverging point of endothelial and hematopoietic lineages. Development 1998;125:1747-1757.
20. Herbst TJ, McCarthy JB, Tsilibary EC, Furcht LT: Differential effects of laminin, intact type IV collagen, and specific domains of type IV collagen on endothelial cell adhesion and migration. J Cell Biol 1988;106:1365-1373.
21. Vittet D, Prandini M-H, Berthier R, Schweitzer A, Martin-Sisteron H, Uzan G, Dejana E: Embryonic stem cells differentiate in vitro to endothelial cells through successive maturation steps. Blood 1996;88:3424-3431.
22. Tufró A: VEGF spatially directs angiogenesis during metanephric development in vitro. Dev Biol 2000;227:558-566.