Characterization and site-directed mutagenesis of the putative novel acyl carrier protein Rv0033 and Rv1344 from Mycobacterium tuberculosis

Biochemical and Biophysical Research Communications

Volumn 342, Issue 2, 2006, Pages 618-624

  Huang, Yishu ^a   Ge, Jing ^a   Yao, Yongchao ^b   Wang, Qingzhong ^a   Shen, Hongbo ^a   Wang, Honghai ^a  

^a FUDAN UNIVERSITY   (China)

^b SHANTOU UNIVERSITY   (China)

Author keywords

Acyl carrier protein; Circular dichroism; Enzyme assay; Homologous model; Site directed mutation; Western blot

Indexed keywords

ACYL CARRIER PROTEIN; FATTY ACID SYNTHASE; MYCOLIC ACID;

ARTICLE; BIOSYNTHESIS; MOLECULAR WEIGHT; MYCOBACTERIUM TUBERCULOSIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SITE DIRECTED MUTAGENESIS; WESTERN BLOTTING;

ACYL CARRIER PROTEIN; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BLOTTING, WESTERN; CIRCULAR DICHROISM; CLONING, MOLECULAR; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; MUTAGENESIS, SITE-DIRECTED; MYCOBACTERIUM TUBERCULOSIS; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT;

MYCOBACTERIUM TUBERCULOSIS;

EID: 33344460710     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.01.178     Document Type: Article

References (28)

1. M.F. Iademarco, and K.G. Castro Epidemiology of tuberculosis Semin. Respir. Infect. 18 2003 225 240
2. L. Wang, R.A. Slayden, C.E. Barry III, and J. Liu Cell wall structure of a mutant of Mycobacterium smegmatis defective in the biosynthesis of mycolic acids J. Biol. Chem. 275 10 2000 7224 7229
3. Y. Yuan, D. Mead, B.G. Schroeder, YaQi Zhu, and C.E. Barry III The biosynthesis of mycolic acids in Mycobacterium tuberculosis J. Biol. Chem. 273 33 1998 21282 21290 Issue of August 14
4. S. Donadio, M.J.K. Staver, J.B. McAlpine, S.J. Swanson, and L. Katz Modular organization of genes required for complex polyketide biosynthesis Science 252 1991 675 679
5. J.-P. Issartel, V. Koronakis, and C. Hughes Activation of Escherichia coli prohaemolysin to the mature toxin by acyl carrier protein-dependent fatty acylation Nature 351 1991 759 761
6. D.J. Prescott, and P.R. Vegelos Acyl carrier protein Adv. Enzymol. Relat. Areas Mol. Biol. 36 1972 269 311
7. C.O. Rock, and S. Jackowski Regulation of phospholipid synthesis in Escherichia coli: composition of the acyl-acyl carrier protein pool in vivo J. Biol. Chem. 257 1982 10759 10765
8. M.S. Anderson, and C.R. Raetz Biosynthesis of lipid A precursors in Escherichia coli: a cytoplasmic acyltransferase that converts UDP-N-acetylglucosamine to UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine J. Biol. Chem. 262 1987 5159 5169
9. S.W. Jordan, and J.E. Cronan A new metabolic link: the acyl carrier protein of lipid synthesis donates lipoic acid to the pyruvate dehydrogenase complex in Escherichia coli and mitochondria J. Biol. Chem. 272 1997 17903 17906
10. I. Sanyal, S.L. Lee, and D.H. Flint Biosynthesis of pimeloyl-CoA, a biotin precursor in Escherichia coli, follows a modified fatty acid synthesis pathway: C-labeling studies J. Am. Chem. Soc. 116 1994 2637 2638
11. A.L. Schaefer, D.L. Val, B.L. Hanzelka, J.E. Cronan Jr., and E.P. Greenberg Generation of cell-to-cell signals in quorum sensing: acyl homoserine lactone synthase activity of a purified Vibrio fischeri LuxI protein Proc. Natl. Acad. Sci. USA 93 1996 9505 9509
12. J.P. Issartel, V. Koronakis, and C. Huges Activation of Escherichia coli prohaemolysin to the mature toxin by acyl carrier proteindependent fatty acylation Nature 351 1991 759 761
13. B. Shen, R.G. Summers, H. Gramajo, M.J. Bibb, and C.R. Hutichinson Purification and characterization of the acyl carrier protein of the Streptomyces glaucescens tetracenomycin C polypeptide synthase J. Bacteriol. 174 1992 3818 3821
14. O. Geiger, H.P. Spaink, and E.P. Kennedy Isolation of the Rhizobium leguminosarum NodF nodulation protein: NodF carries a 40-phosphopantetheine prosthetic group J. Bacteriol. 173 1991 2872 2878
15. M.P. Heaton, and F.C. Neuhaus Role of the d-alanyl carrier protein in the biosynthesis of d-alanyl-lipoteichoic acid J. Bacteriol. 176 3 1994 681 690
16. Y.M. Zhang, H. Marrakchi, S.W. White, and C.O. Rock The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase J. Lipid Res. 44 2003 1 10
17. R.H. Lambalot, and C.T. Walsh Cloning, overproduction, and characterization of the Escherichia coli holo-acyl carrier protein synthase J. Biol. Chem. 270 42 1995 24658 24661
18. R.S. Flugel, Y. Hwangbo, R.H. Lambalot, J.E. Cronan Jr., and C.T. Walsh Holo-(acyl carrier protein) synthase and phosphopantetheinyl transfer in Escherichia coli J. Biol. Chem. 275 2000 959 968
19. Y.M. Zhang, B. Wu, J. Zheng, and C.O. Rock Key residues responsible for acyl carrier protein and b-ketoacyl-acyl carrier protein reductase (FabG) interaction J. Biol. Chem. 278 2003 52935 52943
20. L. Kremer, K.M. Nampoothiri, S. Lesjean, L.G. Dover, S. Graham, J. Betts, P.J. Brennan, D.E. Minnikin, C. Locht, and G.S. Besra Biochemical characterization of acyl carrier protein (AcpM) and malonyl-CoA:AcpM transacylase (mtFabD), two major components of Mycobacterium tuberculosis fatty acid synthase II J. Biol. Chem. 276 30 2001 27967 27974
21. H.C. Wong, G. Liu, Y.M. Zhang, C.O. Rock, and J. Zheng The solution structure of acyl carrier protein from Mycobacterium tuberculosis J. Biol. Chem. 277 18 2002 15874 15880 [Epub 2002 Feb 1]
22. J. Molnos, R. Gardiner, G.E. Dale, and R. Lange A continuous coupled enzyme assay for bacterial malonyl-CoA:acyl carrier protein transacylase (FabD) Anal. Biochem. 319 2003 171 176
23. H. Schulz On the structure-function relationship of acyl carrier protein of Escherichia coli J. Biol. Chem. 250 6 1975 2299 2304
24. C.E. Barry III, R.E. Lee, K. Mdluli, A.E. Sampson, B.J. Schroeder, R.A. Slayden, and Y. Yuan Mycolic acids: structure, biosynthesis and physiological functions Prog. Lipid Res. 37 1998 143 179
25. S.T. Cole, R. Brosch, J. Parkhill, T. Garnier, C. Churcher, D. Harris, S.V. Gordon, K. Eiglmeier, S. Gas, C.E. Barry III, F. Tekaia, K. Badcock, D. Basham, D. Brown, T. Chillingworth, R. Connor, R. Davies, K. Devlin, T. Feltwell, S. Gentles, N. Hamlin, S. Holroyd, T. Hornsby, K. Jagels, A. Krogh, J. McLean, S. Moule, L. Murphy, S. Oliver, J. Osborne, M.A. Quail, M.A. Rajandream, J. Rogers, S. Rutter, K. Seeger, S. Skelton, S. Squares, R. Sqares, J.E. Sulston, K. Taylor, S. Whitehead, and B.G. Barrel Nature 393 1998 537 544
26. T. Ritsema, A.M. Gehring, A.R. Stuitje, K.M. van der Drift, I. Dandal, R.H. Lambalot, C.T. Walsh, J.E. Thomas-Oates, B.J. Lugtenberg, and H.P. Spaink Functional analysis of an interspecies chimera of acyl carrier proteins indicates a specialized domain for protein recognition Mol. Gen. Genet. 257 1998 641 648
27. Stephen W. White, Jie Zheng, Yong-Mei Zhang, and Charles O. Rock The structural biology OF type II fatty acid Biosynthesis Annu. Rev. Biochem. 74 2005 791 831
28. Y.M. Zhang, M.W. Frank, K.G. Virga, R.E. Lee, C.O. Rock, and S. Jackowski Acyl carrier protein is a cellular target for the antibacterial action of the pantothenamide class of pantothenate antimetabolites J. Biol. Chem. 279 49 2004 50969 50975 [Epub 2004 Sep 30]