Imbalance between apoptosis and proliferation causes late radiation damage of salivary gland in mouse

Physiological Research

Volumn 55, Issue 1, 2006, Pages 89-95

  Muhvic Urek, M ^a   Bralic, M ^a   Curic, S ^b   Pezelj Ribaric, S ^a   Borcic, J ^a   Tomac, J ^a  

^a UNIVERSITY OF RIJEKA   (Croatia)

^b UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

Apoptosis; Irradiation; Late post irradiation phase; Proliferation; Salivary glands

Indexed keywords

CYCLINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATROPHY; CELL INFILTRATION; CELL PROLIFERATION; CELL VACUOLE; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; MALE; MONONUCLEAR CELL; MOUSE; NICK END LABELING; NONHUMAN; RADIATION DOSE; RADIATION INJURY; SALIVARY GLAND; SALIVARY GLAND DISEASE; SUBMANDIBULAR GLAND; X RAY; XEROSTOMIA;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; MALE; MICE; MICE, INBRED C57BL; SALIVARY GLANDS; SUBMANDIBULAR GLAND; TIME FACTORS;

EID: 33244454734     PISSN: 08628408     EISSN: 08628408     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. ACTIS AB, LAMPE PD, EYNARD AR: Cellular basis and clinical implications of biological markers in salivary tissues: their topological distribution in murine submandibular gland. Oral Oncol 38: 441-9, 2002.
2. AHLNER BH, HAGELQVIST E, LIND MG, RUDEN BI: Irradiation of rabbit submandibular glands. Histology and morphometry after 15 Gy. Acta Otolaryngol 113: 210-219, 1993.
3. BAEHRECKE EH: How death shapes life during development. Nat Rev Mol Cell Biol 3: 779-787, 2002.
4. BELKA C, JENDROSSEK V, PRUSCHY M, VINK S, VERHEIJ M, BUDACH W. Apoptosis-modulating agents in combination with radiotherapy-current status and outlook. Int J Radiat Oncol Biol Phys 58: 542-554, 2004.
5. BUMP EA, BRAUNHUT SJ, PALAYOOR ST, MEDEIROS D, LAI LL, CERCE BA, LANGLEY RE, COLEMAN CN: Novel concepts in modification of radiation sensitivity. Int J Radiat Oncol Biol Phys 29: 249-253, 1994.
6. COPPES RP, ZEILSTRA LJ, VISSINK A, KONINGS AW: Sialogogue-related radioprotection of salivary gland function: the degranulation concept revisited. Radiat Res 148: 240-247, 1997.
7. DENNY PC, DENNY PA: Dynamics of parenchymal cell division, differentiation, and apoptosis in the young adult female mouse submandibular gland. Anat Rec 254: 408-417, 1999.
8. DORR W: Radiobiological models of normal tissue reactions. Strahlenther Onkol 174: 4-7, 1998.
9. DORR W, HENDRY JH: Consequential late effects in normal tissues. Radiother Oncol 61: 223-231, 2001.
10. GIROD SC, PFEIFFER P, RIES J, PAPE HD: Proliferative activity and loss of function of tumour suppressor genes as 'biomarkers' in diagnosis and prognosis of benign and preneoplastic oral lesions and oral squamous cell carcinoma. Br J Oral Maxillofac Surg 36: 252-260, 1998.
11. GUCHELAAR HJ, VERMES A, MEERWALDT JH: Radiation-induced xerostomia: pathophysiology, clinical course and supportive treatment. Support Care Cancer 5: 281-288, 1997.
12. LANGLEY RE, PALAYOOR ST, COLEMAN CN, BUMP EA: Modifiers of radiation-induced apoptosis. Radiat Res 136: 320-326, 1993.
13. LIMESAND KH, BARZEN KA, QUISSELL DO, ANDERSON SM: Synergistic suppression of apoptosis in salivary acinar cells by IGF1 and EGF. Cell Death Differ 10: 345-355, 2003.
14. MACLUSKEY M, CHANDRACHUD LM, PAZOUKI S, GREEN M, CHISHOLM DM, OGDEN GR, SCHOR SL, SCHOR AM: Apoptosis, proliferation, and angiogenesis in oral tissues. Possible relevance to tumor progression. J Pathol 191: 368-375, 2000.
15. MUHVIC-UREK M, BRALIC M, TOMAC J, BORCIC J, UHAC I, GLAZAR I, ANTONIC R, FERRERI S: The early and late effects of X-irradiation on submandibular gland. A morphological study in mice. accepted by Arch Med Res 36: 339-343, 2005.
16. NAGLER RM: Short- and long-term functional vs morphometrical salivary effects of irradiation in a rodent model. Anticancer Res 18: 315-320, 1998.
17. NAGLER RM: Extended-term effects of head and neck irradiation in a rodent. Eur J Cancer 37: 1938-1945, 2001.
18. NAGLER RM: The enigmatic mechanism of irradiation-induced damage to the major salivary glands. Oral Dis 8: 141-146, 2002.
19. NAGLER RM, LAUFER D: Protection against irradiation-induced damage to salivary glands by adrenergic agonist administration. Int J Radiat Oncol Biol Phys 40: 477-481, 1998.
20. NAGLER RM, BAUM BJ, MILLER G, FOX PC: Long-term salivary effects of single-dose head and neck irradiation in the rat. Arch Oral Biol 43: 297-303, 1998.
21. PARIS F, FUKS Z, KANG A, CAPODIECI P, JUAN G, EHLEITER D, HAIMOVITZ-FRIEDMAN A, CORDONCARDO C, KOLESNICK R: Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science 293: 293-297, 2001.
22. PETER B, VAN WAARDE MA, VISSINK A, S-GRAVENMADE EJ, KONINGS AW: Radiation-induced cell proliferation in the parotid and submandibular glands of the rat. Radiat Res 140: 257-265, 1994.
23. PRICE RE, ANG KK, STEPHENS LC, PETERS LJ: Effects of continuous hyperfractionated accelerated and conventionally fractionated radiotherapy on the parotid and submandibular salivary glands of rhesus monkeys. Radiother Oncol 34: 39-46, 1995.
24. ROSS GM: Induction of cell death by radiotherapy. Endocr Relat Cancer 6: 41-44, 1999.
25. ROOS G, LANDBERG G, HUFF JP, HOUGHTEN R, TAKASAKI Y, TAN EM: Analysis of the epitopes of proliferating cell nuclear antigen recognized by monoclonal antibodies. Lab Invest 68: 204-210, 1993.
26. SODICOFF M, CONGER AD, PRATT NE, TREPPER P: Radioprotection by WR-2721 against long-term chronic damage to the rat parotid gland. Radiat Res 76: 172-179, 1978.
27. STEPHENS LC, ANG KK, SCHULTHEISS TE, KING GK, BROCK WA, PETERS LJ: Target cell and mode of radiation injury in rhesus salivary glands. Radiother Oncol 7: 165-174, 1986.
28. TAYLOR SE: Efficacy and economic evaluation of pilocarpine in treating radiation-induced xerostomia. Expert Opin Pharmacother 4: 1489-1497, 2003.
29. TAYLOR SE, MILLER EG: Preemptive pharmacologic intervention in radiation-induced salivary dysfunction. Proc Soc Exp Biol Med 221: 14-26, 1999.
30. VITOLO JM, COTRIM AP, SOWERS AL, RUSSO A, WELLNER RB, PILLEMER SR, MITCHELL JB, BAUM BJ: The stable nitroxide tempol facilitates salivary gland protection during head and neck irradiation in a mouse model. Clin Cancer Res 10: 1807-1812, 2004.