Synthesis and properties of fluorescent cycloSal nucleotides based on the pyrimidine nucleoside m5K and its 2′,3′-dideoxy analog dm5K

European Journal of Organic Chemistry

Volumn , Issue 4, 2006, Pages 924-931

  Jessen, Henning J ^a   Fendrich, Wolfgang ^a   Meier, Chris ^a  

^a UNIVERSITY OF HAMBURG   (Germany)

Author keywords

Antiviral agents; cycloSal triesters; Fluorescence; Nucleosides; Pronucleotides

Indexed keywords

EID: 33144487121     PISSN: 1434193X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ejoc.200500532     Document Type: Article

References (19)

1. E. De Clercq, Nat. Rev. Drug Dixcov. 2002, 1, 13-25.
2. J. Balzarini, Pharm. World Sci. 1994, 16, 113-126.
3. C. Meier, Synlett 1998, 233-242.
4. C. R. Wagner, V. V. Iyer, E. J. McIntee, Med Res. Rev. 2000, 20, 417-451.
5. C. Meier, Mini-Rev. Med. Chem. 2002, 2, 219-234.
6. a) C. Meier, A. Meerbach, J. Balzarini, Front. Biosci 2004, 9, 873-890;
7. b) C. Meier, in Advances in Antiviral Drug Design (Ed.: E. De Clercq), 2004, vol. 4, 147-213.
8. a) J. Balzarini, S. Aquaro, T. Knispel, C. Rampazzo, V. Bianchi, C. F. Perno, E. De Clercq, C. Meier, Mol. Pharmacol. 2000, 58, 928-935;
9. b) J. Balzarini, L. Naesens, S. Aquaro, T. Knispel, C-F. Perno, E. De Clercq, C. Meier, Mol. Pharmacol. 1999, 56, 1354-1361.
10. a) C. Meier, M. Ruppel, D. Vukadinovic, J. Balzarini, Nucleos. Nucleot. Nucl. 2004, 89-115.
11. C. Meier, H. Jessen, C. Ducho, D. Vukadinovic-Tenter, Eur. J. Org. Chem., in press.
12. P. Wu, T. M. Nordlund, B. Gildea, L. W. McLaughlin, Biochemistry 1990, 29, 6508-6514.
13. S. G. Laland, G. S. Hannssen, Biochem. J. 1964, 90, 76-81.
14. a) D. Cech, A. Holy, Collect. Czech. Chem. Commun. 1977, 42, 2246-2260;
15. b) B. Gildea, L. W. McLaughlin, Nucleic Acids Res. 1989, 17, 2261-2281.
16. A. Whightman, A. Holy, Collect. Czech. Chem. Commun. 1973, 38, 1381-1396.
17. S. F. Singleton, F. Shan, M. W. Kanan, C. M. McIntosh, C. J. Stearman, J. S. Helm, K. J. Webb, Org. Lett. 2001, 3, 3919-3922.
18. V.-Z. Xu, Q. Zheng, P. F. Swann, J. Org. Chem. 1992, 57, 3839-3845.
19. [14]