A novel alternative splicing isoform of human T-cell leukemia virus type 1 bZIP factor (HBZ-SI) targets distinct subnuclear localization

Journal of Virology

Volumn 80, Issue 5, 2006, Pages 2495-2505

  Murata, Ken ^a,c   Hayashibara, Toshihisa ^a,d   Sugahara, Kazuyuki ^a   Uemura, Akiko ^a   Yamaguchi, Taku ^b   Harasawa, Hitomi ^a   Hasegawa, Hiroo ^a   Tsuruda, Kazuto ^a   Okazaki, Toshiro ^a   Koji, Takehiko ^a   Miyanishi, Takayuki ^b   Yamada, Yasuaki ^a   Kamihira, Shimeru ^a  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

^c TOTTORI UNIVERSITY   (Japan)

^d FUJITSU LABORATORIES LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; COMPLEMENTARY DNA; ISOPROTEIN; LEUCINE ZIPPER PROTEIN;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ALTERNATIVE RNA SPLICING; AMINO TERMINAL SEQUENCE; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CONTROLLED STUDY; EXON; GENE AMPLIFICATION; HBZ GENE; HUMAN; HUMAN CELL; HUMAN T CELL LEUKEMIA VIRUS; LONG TERMINAL REPEAT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; T CELL LEUKEMIA; VIRUS GENE; VIRUS GENOME; WESTERN BLOTTING;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ARTIFICIAL GENE FUSION; BASE SEQUENCE; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL NUCLEUS; GREEN FLUORESCENT PROTEINS; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMANS; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; PROTEIN ISOFORMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; RNA, VIRAL; SEQUENCE ANALYSIS, DNA; VIRAL PROTEINS;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN T-LYMPHOTROPIC VIRUS 1;

EID: 33144467800     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.80.5.2495-2505.2006     Document Type: Article

References (34)

1. Angel, P., and M. Karin. 1991. The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim. Biophys. Acta 1072:129-157.
2. Basbous, J., C. Arpin, G. Gaudray, M. Piechaczyk, C. Devaux, and J. M. Mesnard. 2003. The HBZ factor of human T-cell leukemia virus type I dimerizes with transcription factors JunB and c-Jun and modulates their transcriptional activity. J. Biol. Chem. 278:43620-43627.
3. Calnek, B. W. 1986. Marek's disease-a model for herpesvirus oncology. Crit. Rev. Microbiol. 12:293-320.
4. Cereseto, A., F. Diella, J. C. Mulloy, A. Cara, P. Michieli, R. Grassmann, G. Franchini, and M. E. Klotman. 1996. p53 functional impairment and high p21waf1/cip1 expression in human T-cell lymphotropic/leukemia virus type I-transformed T cells. Blood 88:1551-1560.
5. Furukawa, Y., R. Kubota, M. Tara, S. Izumo, and M. Osame. 2001. Existence of escape mutant in HTLV-1 tax during the development of adult T-cell leukemia. Blood 97:987-993.
6. Gaudray, G., F. Gachon, J. Basbous, M. Biard-Piechaczyk, C. Devaux, and J. M. Mesnard. 2002. The complementary strand of the human T-cell leukemia virus type 1 RNA genome encodes a bZIP transcription factor that down-regulates viral transcription. J. Virol. 76:12813-12822.
7. Ginisty, H., F. Amalric, and P. Bouvet. 1998. Nucleolin functions in the first step of ribosomal RNA processing. EMBO J. 17:1476-1486.
8. Grassmann, R., S. Berchtold, I. Radant, M. Alt, B. Fleckenstein, J. G. Sodroski, W. A. Haseltine, and U. Ramstedt. 1992. Role of human T-cell leukemia virus type 1 X region proteins in immortalization of primary human lymphocytes in culture. J. Virol. 66:4570-4575.
9. Hatta, Y., T. Hirama, C. W. Miller, Y. Yamada, M. Tomonaga, and H. P. Koeffler. 1995. Homozygous deletions of the p15 (MTS2) and p16 (CDKN2/MTS1) genes in adult T-cell leukemia. Blood 85:2699-2704.
10. Hayashibara, T., Y. Yamada, S. Nakayama, H. Harasawa, K. Tsuruda, K. Sugahara, T. Miyanishi, S. Kamihira, M. Tomonaga, and T. Maita. 2002. Resveratrol induces downregulation in survivin expression and apoptosis in HTLV-1-infected cell lines: a prospective agent for adult T cell leukemia chemotherapy. Nutr. Cancer 44:193-201.
11. Hinuma, Y., K. Nagata, M. Hanaoka, M. Nakai, T. Matsumoto, K. I. Kinoshita, S. Shirakawa, and I. Miyoshi. 1981. Adult T-cell leukemia: antigen in an ATL cell line and detection of antibodies to the antigen in human sera. Proc. Natl. Acad. Sci. USA 78:6476-6480.
12. Hivin, P., M. Frederic, C. Arpin-Andre, J. Basbous, B. Gay, S. Thebault, and J. M. Mesnard. 2005. Nuclear localization of HTLV-I bZIP factor (HBZ) is mediated by three distinct motifs. J. Cell Sci. 118:1355-1362.
13. Jeang, K. T., C. Z. Giam, F. Majone, and M. Aboud. 2004. Life, death, and tax: role of HTLV-I oncoprotein in genetic instability and cellular transformation. J. Biol. Chem. 279:31991-31994.
14. Jin, D. Y., F. Spencer, and K. T. Jeang. 1998. Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1. Cell 93:81-91.
15. Jones, D., L. Lee, J. L. Liu, H. J. Kung, and J. K. Tillotson. 1992. Marek disease virus encodes a basic-leucine zipper gene resembling the fos/jun oncogenes that is highly expressed in lymphoblastoid tumors. Proc. Natl. Acad. Sci. USA 89:4042-4046.
16. Kato, S., and K. Hirai. 1985. Marek's disease virus. Adv. Virus Res. 30:225-277.
17. Larocca, D., L. A. Chao, M. H. Seto, and T. K. Brunck. 1989. Hum. T-cell leukemia virus minus strand transcription in infected T-cells. Biochem. Biophys. Res. Commun. 163:1006-1013.
18. Le Naour, F., L. Hohenkirk, A. Grolleau, D. E. Misek, P. Lescure, J. D. Geiger, S. Hanash, and L. Beretta. 2001. Profiling changes in gene expression during differentiation and maturation of monocyte-derived dendritic cells using both oligonucleotide microarrays and proteomics. J. Biol. Chem. 276:17920-17931.
19. Liu, J. L., L. F. Lee, Y. Ye, Z. Qian, and H. J. Kung. 1997. Nucleolar and nuclear localization properties of a herpesvirus bZIP oncoprotein, MEQ. J. Virol. 71:3188-3196.
20. Liu, J. L., Y. Ye, L. F. Lee, and H. J. Kung. 1998. Transforming potential of the herpesvirus oncoprotein MEQ: morphological transformation, serum-independent growth, and inhibition of apoptosis. J. Virol. 72:388-395.
21. Maruyama, M., H. Shibuya, H. Harada, M. Hatakeyama, M. Seiki, T. Fujita, J. Inoue, M. Yosbida, and T. Taniguchi. 1987. Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-1-encoded p40x and T3/Ti complex triggering. Cell 48:343-350.
22. Matsumoto, J., T. Ohshima, O. Isono, and K. Shimotohno. 2005. HTLV-1 HBZ suppresses AP-1 activity by impairing both the DNA-binding ability and the stability of c-Jun protein. Oncogene 24:1001-1010.
23. Matsuoka, M. 2003. Human T-cell leukemia virus type I and adult T-cell leukemia. Oncogene 22:5131-5140.
24. Murata, K., M. Fujita, T. Honda, Y. Yamada, M. Tomonaga, and H. Shiku. 1996. Rat primary T cells expressing HTLV-I tax gene transduced by a retroviral vector: in vitro and in vivo characterization. Int. J. Cancer 68:102-108.
25. Neuveut, C., K. G. Low, F. Maldarelli, I. Schmitt, F. Majone, R. Grassmann, and K. T. Jeang. 1998. Human T-cell leukemia virus type 1 Tax and cell cycle progression: role of cyclin D-cdk and p110Rb. Mol. Cell. Biol. 18:3620-3632.
26. Okazaki, S., R. Moriuchi, N. Yosizuka, K. Sugahara, T. Maeda, I. Jinnai, M. Tomonaga, S. Kamihira, and S. Katamine. 2001. HTLV-1 proviruses encoding non-functional TAX in adult T-cell leukemia. Virus Genes 23:123-135.
27. Reitz, M. S. J., B. J. Poiesz, F. W. Ruscetti, and R. C. Gallo. 1981. Characterization and distribution of nucleic acid sequences of a novel type C retrovirus isolated from neoplastic human T lymphocytes. Proc. Natl. Acad. Sci. USA 78:1887-1891.
28. Shimoyama, M. 1991. Diagnostic criteria and classification of clinical subtypes of adult T-cell leukaemia-lymphoma. A report from the Lymphoma Study Group (1984-87). Br. J. Haematol. 79:428-437.
29. Siekevitz, M., M. B. Feinberg, N. Holbrook, F. Wong-Staal, and W. C. Greene. 1987. Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I. Proc. Natl. Acad. Sci. USA 84:5389-5393.
30. Thebault, S., J. Basbous, P. Hivin, C. Devaux, and J. M. Mesnard. 2004. HBZ interacts with JunD and stimulates its transcriptional activity. FEBS Lett. 562:165-170.
31. Yamada, Y., M. Fujita, H. Suzuki, S. Atogami, H. Sohda, K. Murata, K. Tsukasaki, S. Momita, T. Kohno, T. Maeda, T. Joh, S. Kmihira, H. Shiku, and M. Tomonaga. 1994. Established IL-2-dependent double-negative (CD4- CD8-) TCR alpha beta/CD3+ ATL cells: induction of CD4 expression. Br. J. Haematol. 88:234-241.
32. Yamada, Y., Y. Ohmoto, T. Hata, M. Yamamura, K. Murata, K. Tsukasaki, T. Kohno, Y. Chen, S. Kamihira, and M. Tomonaga. 1996. Features of the cytokines secreted by adult T cell leukemia (ATL) cells. Leuk. Lymphoma 21:443-447.
33. Yamato, K., T. Oka, M. Hiroi, Y. Iwahara, S. Sugito, N. Tsuchida, and I. Miyoshi. 1993. Aberrant expression of the p53 tumor suppressor gene in adult T-cell leukemia and HTLV-I-infected cells. Jpn. J. Cancer Res. 84:4-8.
34. Yoshizuka, N., R. Moriuchi, T. Mori, K. Yamada, S. Hasegawa, T. Maeda, T. Shimada, Y. Yamada, S. Kamihira, M. Tomonaga, and S. Katamine. 2004. An alternative transcript derived from the trio locus encodes a guanosine nucleotide exchange factor with mouse cell-transforming potential. J. Biol. Chem. 279:43998-44004.