Aminobenzisoxazoles with biaryl P4 moieties as potent, selective, and orally bioavailable factor Xa inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 7, 2006, Pages 1795-1798

  Quan, Mimi L ^a   Han, Qi ^a   Fevig, John M ^a   Lam, Patrick Y S ^a   Bai, Steve ^a   Knabb, Robert M ^a   Luettgen, Joseph M ^a   Wong, Pancras C ^a   Wexler, Ruth R ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Anticoagulants; Factor Xa inhibitors

Indexed keywords

BLOOD CLOTTING FACTOR 10A INHIBITOR; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; RAZAXABAN;

AMINATION; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG POTENCY; DRUG POTENTIATION; DRUG SELECTIVITY; HUMAN; HUMAN CELL; SUZUKI REACTION;

ADMINISTRATION, ORAL; BENZOXAZOLES; BIOLOGICAL AVAILABILITY; FACTOR XA; SERINE PROTEINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33144463180     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.01.010     Document Type: Article

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