Prolongation of pentoxifylline aliphatic side chain positively affects the reversal of P-glycoprotein-mediated multidrug resistance in L1210/VCR line cells

General Physiology and Biophysics

Volumn 24, Issue 4, 2005, Pages 461-466

  Dočolomanský, Peter ^a   Fiablova I ^b   Barancik M ^b   Rybar A ^b   Breier, Albert ^a  

^a INSTITUTE OF MOLECULAR PHYSIOLOGY AND GENETICS   (Slovakia)

^b INSTITUTE OF CHEMISTRY   (Slovakia)

Author keywords

Alkykl xanthines; L1210 cell line; Multidrug resistance; P glycoprotein; Pentoxifylline analogues

Indexed keywords

1 (10 UNDECYLENYL) 3 HEPTYL 7 METHYLXANTHINE; CARBOHYDRATE; GLYCOPROTEIN P; GLYCOPROTEIN P INHIBITOR; METHYL GROUP; METHYLXANTHINE DERIVATIVE; PENTOXIFYLLINE; PROPANE; UNCLASSIFIED DRUG; VINCRISTINE;

ALKYLATION; ANIMAL CELL; ARTICLE; CELL LINE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG EFFICACY; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SYNTHESIS; EXPERIMENTAL DESIGN; INFRARED RADIATION; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; SUBSTITUTION REACTION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; LEUKEMIA L1210; MICE; P-GLYCOPROTEIN; PENTOXIFYLLINE; STRUCTURE-ACTIVITY RELATIONSHIP; VINCRISTINE; XANTHINE;

ANIMALIA;

EID: 33144459191     PISSN: 02315882     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

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