Association of clinical status of follicular lymphoma patients after autologous stem cell transplant and quantitative assessment of lymphoma in blood and bone marrow as measured by SYBR Green I polymerase chain reaction

Journal of Molecular Diagnostics

Volumn 8, Issue 1, 2006, Pages 40-50

  Pennell, Nancy ^a   Woods, Anthony ^a   Reis, Marciano ^a,b   Buckstein, Rena ^a,b   Spaner, David ^a,b   Imrie, Kevin ^a,b   Hewitt, Karen ^a   Boudreau, Angela ^a   Seth, Arun ^a,b   Berinstein, Neil L ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ANTHRACYCLINE DERIVATIVE; CARMUSTINE; CISPLATIN; CYCLOPHOSPHAMIDE; CYTARABINE; DEXAMETHASONE; DOXORUBICIN; ETOPOSIDE; FLUORESCENT DYE; GRANULOCYTE COLONY STIMULATING FACTOR; MOLECULAR MARKER; PREDNISONE; SYBR GREEN 1; UNCLASSIFIED DRUG; VINCRISTINE;

ADULT; AGED; ARTICLE; AUTOLOGOUS STEM CELL TRANSPLANTATION; BLOOD SAMPLING; BONE MARROW BIOPSY; CANCER GROWTH; CANCER REGRESSION; CANCER RELAPSE; CLINICAL ARTICLE; CLONAL VARIATION; CONTAMINATION; CONTROLLED STUDY; CORRELATION ANALYSIS; COST BENEFIT ANALYSIS; FEMALE; FOLLICULAR LYMPHOMA; HEALTH STATUS; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MINIMAL RESIDUAL DISEASE; PATIENT MONITORING; POLYMERASE CHAIN REACTION; PREDICTION; QUANTITATIVE ASSAY; REAL TIME POLYMERASE CHAIN REACTION; RELIABILITY; REPRODUCIBILITY; SENSITIVITY ANALYSIS;

EID: 32944474543     PISSN: 15251578     EISSN: None     Source Type: Journal    
DOI: 10.2353/jmoldx.2006.050050     Document Type: Article

References (33)

1. Graninger WB, Seto M, Boutain B, Goldman P, Korsmeyer SJ: Expression of Bcl-2 and Bcl-2-Ig fusion transcripts in normal and neoplastic cells. J Clin Invest 1987, 80:1512-1515
2. Godon A, Moreau A, Talmant P, Baranger-Papot L, Genevieve F, Milpied N, Zandecki M, Avet-Loiseau H: Is t(14;18)(q32;q21) a constant finding in follicular lymphoma? An interphase FISH study on 63 patients. Leukemia 2003, 17:255-259
3. Akasaka T, Akasaka H, Yonetani N, Ohno H, Yamabe H, Fukuhara S, Okuma M: Refinement of the BCL2/immunoglobulin heavy chain fusion gene in t(14;18)(q32;q21) by polymerase chain reaction amplification for long targets Genes Chromosom Cancer 1998, 21:17-29
4. Buchonnet G, Jardin F, Jean N, Bertrand P, Parmentier F, Tison S, Lepretre S, Contentin N, Lenain P, Stamatoullas-Bastard A, Tilly H, Bastard C: Distribution of BCL2 breakpoints in follicular lymphoma and correlation with clinical features: specific subtypes or same disease? Leukemia 2002, 16:1852-1856
5. van Dongen JJ, Langerak AW, Bruggemann M, Evans PA, Hummel M, Lavender FL, Delabesse E, Davi F, Schuuring E, Garcia-Sanz R, van Krieken JH, Droese J, Gonzalez D, Bastard C, White HE, Spaargaren M, Gonzalez M, Parreira A, Smith JL, Morgan GJ, Kneba M, Macintyre EA: Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia 2003, 17:2257-2317
6. Hirt C, Schuler F, Dolken G: Minimal residual disease (MRD) in follicular lymphoma in the era of immunotherapy with rituximab. Semin Cancer Biol 2003, 13:223-231
7. von Neuhoff N, Dreger P, Suttorp M, Marget M, Kell S, Schmitz N: Comparison of different strategies of molecular genetic monitoring following autologous stem cell transplantation in patients with follicular lymphoma. Bone Marrow Transplant 1998, 22:161-166
8. Gribben JG, Freedman A, Woo SD, Blake K, Shu RS, Freeman G, Longtine JA, Pinkus GS, Nadler LM: All advanced stage non-Hodgkin's lymphomas with a polymerase chain reaction amplifiable breakpoint of bcl-2 have residual cells containing the bcl-2 rearrangement at evaluation and after treatment. Blood 1991, 78:3275-3280
9. van der Velden VH, Hochhaus A, Cazzaniga G, Szczepanski T, Gabert J, van Dongen JJ: Detection of minimal residual disease in hematologic malignancies by real-time quantitative PCR: principles, approaches, and laboratory aspects. Leukemia 2003, 17:1013-1034
10. Sanchez-Vega B, Vega F, Medeiros LJ, Lee MS, Luthra R: Quantification of bcl-2/JH fusion sequences and a control gene by multiplex real-time PCR coupled with automated amplicon sizing by capillary electrophoresis. J Mol Diagn 2002, 4:223-229
11. Luthra R, McBride JA, Cabanillas F, Sarris A: Novel 5′ exonuclease-based real-time PCR assay for the detection of t(14;18)(q32;q21) in patients with follicular lymphoma. Am J Pathol 1998, 153:63-68
12. Olsson K, Gerard CJ, Zehnder J, Jones C, Ramanathan R, Reading C, Hanania EG: Real-time t(11;14) and t(14;18) PCR assays provide sensitive and quantitative assessments of minimal residual disease (MRD). Leukemia 1999, 13:1833-1842
13. Ladetto M, Sametti S, Donovan JW, Ferrero D, Astolfi M, Mitterer M, Ricca I, Drandi D, Corradini P, Coser P, Pileri A, Gribben JG, Tarella C: A validated real-time quantitative PCR approach shows a correlation between tumor burden and successful ex vivo purging in follicular lymphoma patients. Exp Hematol 2001, 29:183-193
14. Hirt C, Dolken G: Quantitative detection of t(14;18)-positive cells in patients with follicular lymphoma before and after autologous bone marrow transplantation. Bone Marrow Transplant 2000, 25:419-426
15. Ghielmini M, Schmitz SF, Cogliatti SB, Pichert G, Hummerjohann J, Waltzer U, Fey MF, Betticher DC, Martinelli G, Peccatori F, Hess U, Zucca E, Stupp R, Kovacsovics T, Helg C, Lohri A, Bargetzi M, Vorobiof D, Cerny T: Prolonged treatment with rituximab in patients with follicular lymphoma significantly increases event-free survival and response duration compared with the standard weekly × 4 schedule. Blood 2004, 103:4416-4423
16. Jenner MJ, Summers KE, Norton AJ, Amess JA, Arch RS, Young BD, Lister TA, Fitzgibbon J, Goff LK: JH probe real-time quantitative polymerase chain reaction assay for Bcl-2/IgH rearrangements. Br J Haematol 2002, 118:550-558
17. Donovan JW, Ladetto M, Zou G, Neuberg D, Poor C, Bowers D, Gribben JG: Immunoglobulin heavy-chain consensus probes for real-time PCR quantification of residual disease in acute lymphoblastic leukemia. Blood 2000, 95:2651-2658
18. Yashima A, Maesawa C, Uchiyama M, Tarusawa M, Satoh T, Satoh M, Enomoto S, Sugawara K, Numaoka H, Murai K, Utsugisawa T, Ishida Y, Masuda T: Quantitative assessment of contaminating tumor cells in autologous peripheral blood stem cells of B-cell non-Hodgkin lymphomas using immunoglobulin heavy chain gene allele-specific oligonucleotide real-time quantitative-polymerase chain reaction. Leuk Res 2003, 27:925-934
19. Galimberti S, Guerrini F, Morabito F, Palumbo GA, Di Raimondo F, Papineschi F, Caracciolo F, Fazzi R, Cervetti G, Cuzzocrea A, Petrini M: Quantitative molecular evaluation in autotransplant programs for follicular lymphoma: efficacy of in vivo purging by Rituximab. Bone Marrow Transplant 2003, 32:57-63
20. Bohling SD, King TC, Wittwer CT, Elenitoba-Johnson KS: Rapid simultaneous amplification and detection of the MBR/JH chromosomal translocation by fluorescence melting curve analysis. Am J Pathol 1999, 154:97-103
21. Harris NL, Jaffe ES, Diebold J, Flandrin G, Muller-Hermelink HK, Vardiman J, Lister TA, Bloomfield CD: World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues: report of the Clinical Advisory Committee meeting-Airlie House, Virginia, November 1997. J Clin Oncol 1999, 17:3835-3849
22. Iqbal S, Jenner MJ, Summers KE, Davies AJ, Matthews J, Norton AJ, Calaminici M, Rohatiner AZ, Fitzgibbon J, Lister TA, Goff LK: Reliable detection of clonal IgH/Bcl2 MBR rearrangement in follicular lymphoma: methodology and clinical significance. Br J Haematol 2004, 124:325-328
23. Zarrin AA, Fong I, Malkin L, Marsden PA, Berinstein NL: Cloning and characterization of the human recombination activating gene 1 (RAG1) and RAG2 promoter regions. J Immunol 1997, 159:4382-4394
24. Mehra S, Messner H, Minden M, Chaganti RS: Molecular cytogenetic characterization of non-Hodgkin lymphoma cell lines. Genes Chromosom Cancer 2002, 33:225-234
25. Andersen NS, Donovan JW, Borus JS, Poor CM, Neuberg D, Aster JC, Nadler LM, Freedman AS, Gribben JG: Failure of immunologic purging in mantle cell lymphoma assessed by polymerase chain reaction detection of minimal residual disease. Blood 1997, 90:4212-4221
26. Coad JE, Olson DJ, Christensen DR, Lander TA, Chibbar R, McGlennen RC, Brunning RD: Correlation of PCR-detected clonal gene rearrangements with bone marrow morphology in patients with B-lineage lymphomas. Am J Surg Pathol 1997, 21:1047-1056
27. Hostein I, Menard A, Soubeyran I, Eghbali H, Debled M, Gastaldello B, Soubeyran P: A 1-kb Bcl-2-PCR fragment detection in a patient with follicular lymphoma and development of a new diagnostic PCR method. Diagn Mol Pathol 2001, 10:89-94
28. Berinstein NL, Jamal HH, Kuzniar B, Klock RJ, Reis MD: Sensitive and reproducible detection of occult disease in patients with follicular lymphoma by PCR amplification of t(14;18) both pre- and post-treatment. Leukemia 1993, 7:113-119
29. Yuan R, Dowling P, Zucca E, Diggelmann H, Cavalli F: Detection of bcl-2/JH rearrangement in follicular and diffuse lymphoma: concordant results of peripheral blood and bone marrow analysis at diagnosis. Br J Cancer 1993, 67:922-925
30. Gribben JG, Neuberg D, Barber M, Moore J, Pesek KW, Freedman AS, Nadler LM: Detection of residual lymphoma cells by polymerase chain reaction in peripheral blood is significantly less predictive for relapse than detection in bone marrow. Blood 1994, 83:3800-3807
31. Rambaldi A, Carlotti E, Oldani E, Della Starza I, Baccarani M, Cortelazzo S, Lauria F, Arcaini L, Morra E, Pulsoni A, Rigacci L, Rupolo M, Zaja F, Zinzani PL, Barbui T, Foa R: Quantitative PCR of bone marrow BCL2/IgH+ cells at diagnosis predicts treatment response and long-term outcome in follicular non-Hodgkin lymphoma. Blood 2005, 105:3428-3433
32. Ladetto M, Mantoan B, Ricca I, Astolfi M, Drandi D, Compagno M, Vallet S, dell'Aquila M, Alfarano A, Rossatto P, Rocci A, Vitolo U, Corradini P, Boccadoro M, Tarella C: Recurrence of Bcl-2/IgH polymerase chain reaction positivity following a prolonged molecular remission can be unrelated to the original follicular lymphoma clone. Exp Hematol 2003, 31:784-788
33. Dolken L, Schuler F, Dolken G: Quantitative detection of t(14;18)-positive cells by real-time quantitative PCR using fluorogenic probes. Biotechniques 1998, 25:1058-1064