Suppressive effects of GTW treatment on mesangial lesions in experimental irreversible glomerulosclerosis

Zhongguo Zhongyao Zazhi

Volumn 30, Issue 5, 2005, Pages 361-365

  Wan, Yi Gang ^a,b   Sun, Wei ^c   Shmizu, Fujio ^b   Gu, Liu Bao ^d   Suziki, Koichi ^b   Karasawa, Tamaki ^b   Kawachi, Hiroshi ^b  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^b NIIGATA UNIVERSITY   (Japan)

^c NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^d BEIJING HOSPITAL   (China)

Author keywords

Cytokine; Glomerulosclerosis; Multi glycoside of Tripterygium wilfordii (GTW)

Indexed keywords

ACTININ; COLLAGEN TYPE 1; GLYCOSIDE; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL; ARTICLE; BIOSYNTHESIS; CHEMISTRY; FEMALE; GENETICS; ISOLATION AND PURIFICATION; MEDICINAL PLANT; MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS; MESANGIUM; METABOLISM; PATHOLOGY; PROTEINURIA; RAT; TRIPTERYGIUM; WISTAR RAT;

ACTININ; ANIMALS; COLLAGEN TYPE I; FEMALE; GLOMERULAR MESANGIUM; GLOMERULONEPHRITIS, MEMBRANOPROLIFERATIVE; GLYCOSIDES; PLANTS, MEDICINAL; PROTEINURIA; RATS; RATS, WISTAR; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA; TRIPTERYGIUM;

EID: 32644448647     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Wan YG, Gu L B, Shimizu F. Mechanism of protective effects of effective components in Ttipterygium wilfordii hook. f. on glomerulonephritis (Article in Japanese). J Clin and Exp Med, 2003,207: 285.
2. Rong S, Hu W X, Liu ZH, et al. A new regime of Tripterygium wilfordii hook. f. in treating primary mesangial proliferative glomerulonephritis(Article in Chinese). J Nephrol Dialy Transplant, 1998, 7:409.
3. Qiu D, Kao P N. Immunosuppressive and anti-inflammatory mechanisms of Tliptolide, the principal active diterpenoid from the Chinese Medicinal Herb Tripterygium wilfordii hook. f. Drugs R D, 2003, 4:1.
4. Shimizu F, Kawachi H, Orikasa M. Role of mesangial Cell Damage in Progressive Renal Disease. Kidney Blood Press Res, 1999,22:5.
5. Raij L, Azar S, Keane W F. Mesangial injury, hypertension, and progressive glomerular damage in Dahl rats. Kidney Int, 1984,26: 137.
6. Chu M, Meyers J, Bernanrd M, et al. Cloning and characterization of five overlapping cDNA specific the human pro α1(I) collagen chain. Nucl Acid Res, 1982,10:5925.
7. Tsuji T, Okada F, Yamaguchi K, et al. Molecular cloning of the large subunit of transforming growth factor type β masking protein and expression of the mRNA in various rat tissues. Proc Natl Acad Sci USA, 1990,87:8835.
8. Floege J, Johnson R J, Gordon K, et al. Increased synthesis of extracellular matrix in mesangial proliferative nephritis. Kidney Int, 1991,40:477.
9. Kawachi H, Iwanaga T, Toyabe S, et al. Mesangial sclerotic change with persistent proteinuria in rats after two consecutive injections of monoclonal antibody 1-22-3. Clin Exp Immunol, 1992,90:129.
10. Kawachi H, Orikasa M, Matsui K, et al. Epitope-specific induction of mesangial lesion with proteinuria by a MoAb against mesangial cell surface antigen. Clin Exp Immunol, 1992, 88:399.
11. Floege J, Johnson R J, Gordon K, et al. Increased synthesis of extracellular matrix raesangial proliferative nephritis. Kidney Int, 1991, 40:477.
12. Nakayama M, Okuda S, Tamaki K, et al. Roles of TGF-β and Latent TGF-β-Binding Protein in Glomerulosclerosis Induced by Two Consecutive Injections of Monoclonal Antibody 1-22-3 in Rats. Nephron, 1997,76:82.
13. Toshiyuki I, Tadasuke N, Tetsuya M. Mechanism of glomerulosclerosis (Article in Japanese). 1th ed, Tokyo: Renal Disease-state of arts,2003-2005, 2003.68.