A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
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Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
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Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
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Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
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Sustained elevation of extracellular dopamine causes motor dysfunction and selective degeneration of striatal GABAergic neurons
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Rate of caudate atrophy in presymptomatic and symptomatic stages of Huntington's disease
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Differential loss of striatal projection neurons in Huntington disease
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Huntingtin aggregate-associated axonal degeneration is an early pathological event in Huntington's disease mice
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Unraveling a role for dopamine in Huntington's disease: The dual role of reactive oxygen species and D2 receptor stimulation
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