NMR fragment screening: Advantages and applications

IDrugs

Volumn 9, Issue 2, 2006, Pages 110-113

  Schade, Markus ^a  

^a MerLion Pharmaceuticals GmbH   (Germany)

Author keywords

Fragment; Lead discovery; Lead optimization; NMR; Screening

Indexed keywords

1,4 BENZODIOXAN DERIVATIVE; CARBON 13; CINNAMIC ACID DERIVATIVE; DEUTERIUM; INDOLE DERIVATIVE; LIGAND; NITROGEN 15; PDZ PROTEIN; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE; PROTEIN TYROSINE PHOSPHATASE 1B; PROTEINASE; TEMPONE; THIOL DERIVATIVE; WATER;

ANALYTIC METHOD; ARTICLE; BINDING SITE; COMBINATORIAL LIBRARY; DRUG DESIGN; DRUG IDENTIFICATION; DRUG STRUCTURE; HIGH THROUGHPUT SCREENING; ISOTOPE LABELING; MOLECULAR WEIGHT; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PROCESS OPTIMIZATION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN TARGETING; PROTON NUCLEAR MAGNETIC RESONANCE; SENSITIVITY ANALYSIS; SPIN LABELING; STRUCTURE ACTIVITY RELATION;

DRUG DESIGN; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PHARMACOLOGY; PROTEIN BINDING; RECEPTORS, DRUG;

EID: 32544436259     PISSN: 13697056     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

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