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Volumn 76, Issue 1, 2006, Pages 39-45

Role of retinoic acid receptors α1 and γ in the response of murine limbs to retinol in vitro

Author keywords

Chondrogenesis; Limb development; Limb outgrowth; Retinoid teratogenesis

Indexed keywords

GENE PRODUCT; PROTEIN COL12A1; PROTEIN MEIS1; PROTEIN MEIS2; RETINOIC ACID; RETINOIC ACID RECEPTOR ALPHA; RETINOIC ACID RECEPTOR ALPHA1; RETINOIC ACID RECEPTOR GAMMA; RETINOID X RECEPTOR; RETINOL; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG;

EID: 32444450089     PISSN: 15420752     EISSN: None     Source Type: Journal    
DOI: 10.1002/bdra.20219     Document Type: Article
Times cited : (7)

References (42)
  • 1
    • 0036830491 scopus 로고    scopus 로고
    • The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6
    • Akiyama H, Chaboissier MC, Martin JF, et al. 2002. The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. Genes Dev 16:2813-2828.
    • (2002) Genes Dev , vol.16 , pp. 2813-2828
    • Akiyama, H.1    Chaboissier, M.C.2    Martin, J.F.3
  • 2
    • 0242286649 scopus 로고    scopus 로고
    • Caspase-3 mediates retinoid-induced apoptosis in the organogenesis-stage mouse limb
    • Ali-Khan SE, Hales BF. 2003. Caspase-3 mediates retinoid-induced apoptosis in the organogenesis-stage mouse limb. Birth Defects Res Part A Clin Mol Teratol 67:848-860.
    • (2003) Birth Defects Res Part A Clin Mol Teratol , vol.67 , pp. 848-860
    • Ali-Khan, S.E.1    Hales, B.F.2
  • 3
    • 0033395856 scopus 로고    scopus 로고
    • Selective agonists of retinoic acid receptors: Comparative toxicokinetics and embryonic exposure
    • Arafa HM, Elmazar MM, Hamada FM, et al. 2000. Selective agonists of retinoic acid receptors: comparative toxicokinetics and embryonic exposure. Arch Toxicol 73:547-556.
    • (2000) Arch Toxicol , vol.73 , pp. 547-556
    • Arafa, H.M.1    Elmazar, M.M.2    Hamada, F.M.3
  • 4
    • 0031003272 scopus 로고    scopus 로고
    • SOX9 directly regulates the type-II collagen gene
    • Bell DM, Leung KK, Wheatley SC, et al. 1997. SOX9 directly regulates the type-II collagen gene. Nat Genet 16:174-178.
    • (1997) Nat Genet , vol.16 , pp. 174-178
    • Bell, D.M.1    Leung, K.K.2    Wheatley, S.C.3
  • 5
    • 0033561377 scopus 로고    scopus 로고
    • The subcellular localization of PBX1 and EXD proteins depends on nuclear import and export signals and is modulated by association with PREP1 and HTH
    • Berthelsen J, Kilstrup-Nielsen C, Blasi F, et al. 1999. The subcellular localization of PBX1 and EXD proteins depends on nuclear import and export signals and is modulated by association with PREP1 and HTH. Genes Dev 13:946-953.
    • (1999) Genes Dev , vol.13 , pp. 946-953
    • Berthelsen, J.1    Kilstrup-Nielsen, C.2    Blasi, F.3
  • 6
    • 0028894783 scopus 로고
    • Targeted disruption of retinoic acid receptor alpha (RAR alpha) and RAR gamma results in receptor-specific alterations in retinoic acid-mediated differentiation and retinoic acid metabolism
    • Boylan JF, Lufkin T, Achkar CC, et al. 1995. Targeted disruption of retinoic acid receptor alpha (RAR alpha) and RAR gamma results in receptor-specific alterations in retinoic acid-mediated differentiation and retinoic acid metabolism. Mol Cell Biol 15:843-851.
    • (1995) Mol Cell Biol , vol.15 , pp. 843-851
    • Boylan, J.F.1    Lufkin, T.2    Achkar, C.C.3
  • 7
    • 0033231553 scopus 로고    scopus 로고
    • Control of vertebrate limb outgrowth by the proximal factor Meis2 and distal antagonism of BMPs by Gremlin
    • Capdevila J, Tsukui T, Rodriquez Esteban C, et al. 1999. Control of vertebrate limb outgrowth by the proximal factor Meis2 and distal antagonism of BMPs by Gremlin. Mol Cell 4:839-849.
    • (1999) Mol Cell , vol.4 , pp. 839-849
    • Capdevila, J.1    Tsukui, T.2    Rodriquez Esteban, C.3
  • 8
    • 0028419153 scopus 로고
    • The retinoid signaling pathway: Molecular and genetic analyses
    • Chambon P. 1994. The retinoid signaling pathway: molecular and genetic analyses. Semin Cell Biol 5:115-125.
    • (1994) Semin Cell Biol , vol.5 , pp. 115-125
    • Chambon, P.1
  • 9
    • 0024367398 scopus 로고
    • Differential expression of genes encoding alpha, beta and gamma retinoic acid receptors and CRABP in the developing limbs of the mouse
    • Dolle P, Ruberte E, Kastner P, et al. 1989. Differential expression of genes encoding alpha, beta and gamma retinoic acid receptors and CRABP in the developing limbs of the mouse. Nature 342:702-705.
    • (1989) Nature , vol.342 , pp. 702-705
    • Dolle, P.1    Ruberte, E.2    Kastner, P.3
  • 10
    • 0030610023 scopus 로고    scopus 로고
    • RARalpha-mediated teratogenicity in mice is potentiated by an RXR agonist and reduced by an RAR antagonist: Dissection of retinoid receptor-induced pathways
    • Elmazar MM, Ruhl R, Reichert U, et al. 1997. RARalpha-mediated teratogenicity in mice is potentiated by an RXR agonist and reduced by an RAR antagonist: dissection of retinoid receptor-induced pathways. Toxicol Appl Pharmacol 146:21-28.
    • (1997) Toxicol Appl Pharmacol , vol.146 , pp. 21-28
    • Elmazar, M.M.1    Ruhl, R.2    Reichert, U.3
  • 11
    • 0028135336 scopus 로고
    • Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene
    • Foster JW, Dominguez-Steglich MA, Guioli S, et al. 1994. Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene. Nature 372:525-530.
    • (1994) Nature , vol.372 , pp. 525-530
    • Foster, J.W.1    Dominguez-Steglich, M.A.2    Guioli, S.3
  • 12
    • 0034650893 scopus 로고    scopus 로고
    • The coregulator exchange in transcriptional functions of nuclear receptors
    • Glass CK, Rosenfeld MG. 2000. The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev 14:121-141.
    • (2000) Genes Dev , vol.14 , pp. 121-141
    • Glass, C.K.1    Rosenfeld, M.G.2
  • 13
    • 0038077226 scopus 로고    scopus 로고
    • Molecular mechanisms regulating chondroblast differentiation
    • Hoffman LM, Weston AD, Underhill TM. 2003. Molecular mechanisms regulating chondroblast differentiation. J Bone Joint Surg Am 85-A(Suppl 2):124-132.
    • (2003) J Bone Joint Surg Am , vol.85 A , Issue.SUPPL. 2 , pp. 124-132
    • Hoffman, L.M.1    Weston, A.D.2    Underhill, T.M.3
  • 14
    • 0036912334 scopus 로고    scopus 로고
    • Role of caspases in murine limb bud cell death induced by 4-hydroperoxycyclophosphamide, an activated analog of cyclophosphamide
    • Huang C, Hales BF. 2002. Role of caspases in murine limb bud cell death induced by 4-hydroperoxycyclophosphamide, an activated analog of cyclophosphamide. Teratology 66:288-299.
    • (2002) Teratology , vol.66 , pp. 288-299
    • Huang, C.1    Hales, B.F.2
  • 15
    • 0030949889 scopus 로고    scopus 로고
    • Contribution of retinoic acid receptor gamma to retinoid-induced craniofacial and axial defects
    • Iulianella A, Lohnes D. 1997. Contribution of retinoic acid receptor gamma to retinoid-induced craniofacial and axial defects. Dev Dyn 209:92-104.
    • (1997) Dev Dyn , vol.209 , pp. 92-104
    • Iulianella, A.1    Lohnes, D.2
  • 16
    • 0032920244 scopus 로고    scopus 로고
    • A molecular basis for retinoic acid-induced axial truncation
    • Iulianella A, Beckett B, Petkovich M, Lohnes D. 1999. A molecular basis for retinoic acid-induced axial truncation. Dev Biol 205:33-48.
    • (1999) Dev Biol , vol.205 , pp. 33-48
    • Iulianella, A.1    Beckett, B.2    Petkovich, M.3    Lohnes, D.4
  • 17
    • 0031054372 scopus 로고    scopus 로고
    • Genetic evidence that the retinoid signal is transduced by heterodimeric RXR/RAR functional units during mouse development
    • Kastner P, Mark M, Ghyselinck N, et al. 1997. Genetic evidence that the retinoid signal is transduced by heterodimeric RXR/RAR functional units during mouse development. Development 124:313-326.
    • (1997) Development , vol.124 , pp. 313-326
    • Kastner, P.1    Mark, M.2    Ghyselinck, N.3
  • 18
    • 0029959034 scopus 로고    scopus 로고
    • Differential teratogenic response of mouse embryos to receptor selective analogs of retinoic acid
    • Kochhar DM, Jiang H, Penner JD, et al. 1996. Differential teratogenic response of mouse embryos to receptor selective analogs of retinoic acid. Chem Biol Interact 100:1-12.
    • (1996) Chem Biol Interact , vol.100 , pp. 1-12
    • Kochhar, D.M.1    Jiang, H.2    Penner, J.D.3
  • 19
    • 0019194446 scopus 로고
    • Production of congenital limb defects with retinoic acid: Phenomenological evidence of progressive differentiation during limb morphogenesis
    • Kwasigroch TE, Kochhar DM. 1980. Production of congenital limb defects with retinoic acid: phenomenological evidence of progressive differentiation during limb morphogenesis. Anat Embryol (Berl) 161:105-113.
    • (1980) Anat Embryol (Berl) , vol.161 , pp. 105-113
    • Kwasigroch, T.E.1    Kochhar, D.M.2
  • 20
    • 0021167320 scopus 로고
    • Mouse limb bud development in submerged culture: Quantitative assessment of the effects of in vivo exposure to retinoic acid
    • Kwasigroch TE, Skalko RG, Church JK. 1984. Mouse limb bud development in submerged culture: quantitative assessment of the effects of in vivo exposure to retinoic acid. Teratog Carcinog Mutagen 4:311-326.
    • (1984) Teratog Carcinog Mutagen , vol.4 , pp. 311-326
    • Kwasigroch, T.E.1    Skalko, R.G.2    Church, J.K.3
  • 21
    • 0000958271 scopus 로고    scopus 로고
    • Toward understanding SOX9 function in chondrocyte differentiation
    • Lefebvre V, de Crombrugghe B. 1998. Toward understanding SOX9 function in chondrocyte differentiation. Matrix Biol 16:529-540.
    • (1998) Matrix Biol , vol.16 , pp. 529-540
    • Lefebvre, V.1    De Crombrugghe, B.2
  • 22
    • 0026742534 scopus 로고
    • Multiplicity generates diversity in the retinoic acid signalling pathways
    • Leid M, Kastner P, Chambon P. 1992. Multiplicity generates diversity in the retinoic acid signalling pathways. Trends Biochem Sci 17:427-433.
    • (1992) Trends Biochem Sci , vol.17 , pp. 427-433
    • Leid, M.1    Kastner, P.2    Chambon, P.3
  • 24
    • 0028088752 scopus 로고
    • Function of the retinoic acid receptors (RARs) during development (I). Craniofacial and skeletal abnormalities in RAR double mutants
    • Lohnes D, Mark M, Mendelsohn C, et al. 1994. Function of the retinoic acid receptors (RARs) during development (I). Craniofacial and skeletal abnormalities in RAR double mutants. Development 120:2723-2748.
    • (1994) Development , vol.120 , pp. 2723-2748
    • Lohnes, D.1    Mark, M.2    Mendelsohn, C.3
  • 25
    • 0029118396 scopus 로고
    • Mice lacking all isoforms of retinoic acid receptor beta develop normally and are susceptible to the teratogenic effects of retinoic acid
    • Luo J, Pasceri P, Conlon RA, et al. 1995. Mice lacking all isoforms of retinoic acid receptor beta develop normally and are susceptible to the teratogenic effects of retinoic acid. Mech Dev 53:61-71.
    • (1995) Mech Dev , vol.53 , pp. 61-71
    • Luo, J.1    Pasceri, P.2    Conlon, R.A.3
  • 26
    • 0029961041 scopus 로고    scopus 로고
    • Compound mutants for retinoic acid receptor (RAR) beta and RAR alpha 1 reveal developmental functions for multiple RAR beta isoforms
    • Luo J, Sucov HM, Bader JA, et al. 1996. Compound mutants for retinoic acid receptor (RAR) beta and RAR alpha 1 reveal developmental functions for multiple RAR beta isoforms. Mech Dev 55:33-44.
    • (1996) Mech Dev , vol.55 , pp. 33-44
    • Luo, J.1    Sucov, H.M.2    Bader, J.A.3
  • 27
    • 0026597950 scopus 로고
    • Characterization of three RXR genes that mediate the action of 9-cis retinoic acid
    • Mangelsdorf DJ, Borgmeyer U, Heyman RA, et al. 1992. Characterization of three RXR genes that mediate the action of 9-cis retinoic acid. Genes Dev 6:329-344.
    • (1992) Genes Dev , vol.6 , pp. 329-344
    • Mangelsdorf, D.J.1    Borgmeyer, U.2    Heyman, R.A.3
  • 28
    • 0012473279 scopus 로고
    • The nuclear receptor superfamily: The second decade
    • Mangelsdorf DJ, Thummel C, Beato M, et al. 1995. The nuclear receptor superfamily: the second decade. Cell 83:835-839.
    • (1995) Cell , vol.83 , pp. 835-839
    • Mangelsdorf, D.J.1    Thummel, C.2    Beato, M.3
  • 29
    • 0028073019 scopus 로고
    • Function of the retinoic acid receptors (RARs) during development (II). Multiple abnormalities at various stages of organogenesis in RAR double mutants
    • Mendelsohn C, Lohnes D, Decimo D, et al. 1994. Function of the retinoic acid receptors (RARs) during development (II). Multiple abnormalities at various stages of organogenesis in RAR double mutants. Development 120:2749-2771.
    • (1994) Development , vol.120 , pp. 2749-2771
    • Mendelsohn, C.1    Lohnes, D.2    Decimo, D.3
  • 30
    • 0033604502 scopus 로고    scopus 로고
    • Conserved regulation of proximodistal limb axis development by Meis1/Hth
    • Mercader N, Leonardo E, Azpiazu N, et al. 1999. Conserved regulation of proximodistal limb axis development by Meis1/Hth. Nature 402:425-429.
    • (1999) Nature , vol.402 , pp. 425-429
    • Mercader, N.1    Leonardo, E.2    Azpiazu, N.3
  • 31
    • 0033786946 scopus 로고    scopus 로고
    • Opposing RA and FGF signals control proximodistal vertebrate limb development through regulation of Meis genes
    • Mercader N, Leonardo E, Piedra ME, et al. 2000. Opposing RA and FGF signals control proximodistal vertebrate limb development through regulation of Meis genes. Development 127:3961-3970.
    • (2000) Development , vol.127 , pp. 3961-3970
    • Mercader, N.1    Leonardo, E.2    Piedra, M.E.3
  • 32
    • 0012115412 scopus 로고
    • Techniques applicable to study morphogenetic differentiation of limb buds in organ culture
    • Neubert D, Merker H-J, Kwasigroch T, editors Stuttgart: Georg Thieme Publishers
    • Neubert D, Barrach H-J. 1977. Techniques applicable to study morphogenetic differentiation of limb buds in organ culture. In: Neubert D, Merker H-J, Kwasigroch T, editors. Methods in pre-natal toxicology. Stuttgart: Georg Thieme Publishers, pp 241-251.
    • (1977) Methods in Pre-Natal Toxicology , pp. 241-251
    • Neubert, D.1    Barrach, H.-J.2
  • 33
    • 0028587214 scopus 로고
    • Stage- And region-dependent responses of chick wing-bud mesenchymal cells to retinoic acid in serum-free microcultures
    • Paulsen DF, Chen WD, Okello D, Johnson B. 1994. Stage- and region-dependent responses of chick wing-bud mesenchymal cells to retinoic acid in serum-free microcultures. Dev Dyn 201:310-323.
    • (1994) Dev Dyn , vol.201 , pp. 310-323
    • Paulsen, D.F.1    Chen, W.D.2    Okello, D.3    Johnson, B.4
  • 34
    • 0036843726 scopus 로고    scopus 로고
    • PBX, MEIS, and IGF-1 art-potential mediators of retinoic acid-induced proximodistal limb reduction defects
    • Qin P, Cimildoro R, Kochhar DM, et al. 2002. PBX, MEIS, and IGF-1 art-potential mediators of retinoic acid-induced proximodistal limb reduction defects. Teratology 66:224-234.
    • (2002) Teratology , vol.66 , pp. 224-234
    • Qin, P.1    Cimildoro, R.2    Kochhar, D.M.3
  • 36
    • 0035029259 scopus 로고    scopus 로고
    • Transcriptional suppression of Sox9 expression in chondrocytes by retinoic acid
    • Sekiya I, Koopman P, Tsuji K, et al. 2001. Transcriptional suppression of Sox9 expression in chondrocytes by retinoic acid. J Cell Biochem 81: 71-78.
    • (2001) J Cell Biochem , vol.81 , pp. 71-78
    • Sekiya, I.1    Koopman, P.2    Tsuji, K.3
  • 37
    • 0030930611 scopus 로고    scopus 로고
    • Limited specificity and large overlap of the functions of the mouse RAR gamma 1 and RAR gamma 2 isoforms
    • Subbarayan V, Kastner P, Mark M, et al. 1997. Limited specificity and large overlap of the functions of the mouse RAR gamma 1 and RAR gamma 2 isoforms. Mech Dev 66:131-142.
    • (1997) Mech Dev , vol.66 , pp. 131-142
    • Subbarayan, V.1    Kastner, P.2    Mark, M.3
  • 38
    • 0029588405 scopus 로고
    • Mouse embryos lacking RXR alpha are resistant to retinoic-acid-induced limb defects
    • Sucov HM, Izpisua-Belmonte JC, Ganan Y, Evans RM. 1995. Mouse embryos lacking RXR alpha are resistant to retinoic-acid-induced limb defects. Development 121:3997-4003.
    • (1995) Development , vol.121 , pp. 3997-4003
    • Sucov, H.M.1    Izpisua-Belmonte, J.C.2    Ganan, Y.3    Evans, R.M.4
  • 39
    • 0034695925 scopus 로고    scopus 로고
    • Regulation of skeletal progenitor differentiation by the BMP and retinoid signaling pathways
    • Weston AD, Rosen V, Chandraratna RA, Underhill TM. 2000. Regulation of skeletal progenitor differentiation by the BMP and retinoid signaling pathways. J Cell Biol 148:679-690.
    • (2000) J Cell Biol , vol.148 , pp. 679-690
    • Weston, A.D.1    Rosen, V.2    Chandraratna, R.A.3    Underhill, T.M.4
  • 40
    • 0037043331 scopus 로고    scopus 로고
    • Requirement for RAR-mediated gene repression in skeletal progenitor differentiation
    • Weston AD, Chandraratna RA, Torchia J, Underhill TM. 2002. Requirement for RAR-mediated gene repression in skeletal progenitor differentiation. J Cell Biol 158:39-51.
    • (2002) J Cell Biol , vol.158 , pp. 39-51
    • Weston, A.D.1    Chandraratna, R.A.2    Torchia, J.3    Underhill, T.M.4
  • 42
    • 0036829987 scopus 로고    scopus 로고
    • Transcriptional induction of mitogen-activated protein kinase phosphatase 1 by retinoids. Selective roles of nuclear receptors and contribution to the antiapoptotic effect
    • Xu Q, Konta T, Furusu A, et al. 2002. Transcriptional induction of mitogen-activated protein kinase phosphatase 1 by retinoids. Selective roles of nuclear receptors and contribution to the antiapoptotic effect. J Biol Chem 277:41693-41700.
    • (2002) J Biol Chem , vol.277 , pp. 41693-41700
    • Xu, Q.1    Konta, T.2    Furusu, A.3


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