Anorexia: A taste of things to come?

Palliative Medicine

Volumn 20, Issue 1, 2006, Pages 43-45

  Wilcock, Andrew ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AGOUTI RELATED PROTEIN; CYTOKINE; HORMONE RECEPTOR BLOCKING AGENT; MELANOCORTIN 4 RECEPTOR; MELANOCORTIN 4 RECEPTOR ANTAGONIST; NEUROPEPTIDE Y; UNCLASSIFIED DRUG;

ADVANCED CANCER; ANOREXIA; ARTICLE; CACHEXIA; CALORIC INTAKE; CANCER MORTALITY; CANCER PALLIATIVE THERAPY; CANCER PATIENT; FOOD INTAKE; HUMAN; HYPOTHALAMUS; MALNUTRITION; METABOLIC DISORDER; MORBIDITY; MUSCLE MASS; NONHUMAN; PATHOPHYSIOLOGY; QUALITY OF LIFE;

ANIMALS; ANOREXIA; CACHEXIA; CYTOKINES; HUMANS; MICE; NEOPLASMS; RECEPTOR, MELANOCORTIN, TYPE 4;

EID: 32444445041     PISSN: 02692163     EISSN: None     Source Type: Journal    
DOI: 10.1191/0269216306pm1089xx     Document Type: Article

References (13)

1. Pirovano M, Maltoni M, Nanni O, et al. A new palliative care score: a first step for the staging of terminally ill cancer patients. Italian multicenter study group on palliative care. J Pain Symptom Manage 1999; 17: 231-39.
2. Laviano A, Meguid MM, Rossi-Fanelli F. Cancer anorexia: clinical implications, pathogenesis, and therapeutic strategies. Lancet Oncol 2003; 4: 686-94.
3. Markinson S, Foster AC, Chen C, et al. The regulation of feeding and metabolic rate and the prevention of murine cancer cachexia with a small-molecule mealnocortin-4 receptor antagonist. Endocrinology 2005; 146: 2766-73.
4. Schwartz MW, Woods SC, Porte D Jr, et al. Central nervous system control of food intake. Nature 2000; 404: 661-71.
5. Ramos EJB, Meguid MM, Campos ACL, Coelho JCU. Neuropeptide Y, α-melanocyte stimulating hormone, and monoamines in food intake regulation. Nutrition 2005; 21: 269-79.
6. Laviano A, Meguid MM, Inui A, Muscaritoli M, Rossi-Fanelli F. Therapy insight - when all you can eat is yourself. Nature Clin Pract Oncol 2005; 2: 158-65.
7. Ramos EJB, Suzuki S, Marks D, et al. Cancer anorexia-cachexia syndrome: cytokines and neuropeptides. Curr Opin Clin Nutr Metab Care 2004; 7: 427-34.
8. Davis MP, Dreicer R, Walsh D, Langman R, LeGrand SB. Appetite and cancer-associated anorexia: a review. J Clin Oncol 2004; 22: 1510-17.
9. 1B) receptor and NPY in cancer anorexia after tumour resection: an immunocytochemical study. Neurosci Lett 2005; 383: 322-27.
10. Marks DL, Ling N, Cone RD. Role of central melanocortin system in cachexia. Cancer Res 2001; 61: 1432-38.
11. Cheung W, Yu PX, Little BM, et al. Role of leptin and melanocortin signaling in uremia-associated cachexia. J Clin Invest 2005; 115: 1659-65.
12. Vos TJ, Caracoti A, Che JL, et al. Identification of 2-[2-[2-(5-bromo-2-methoxyphenyl)-ethyl] -3-fluorophenyl]-4,5-dihydro-1H-imidazole (ML00253764), a small molecule melanocortin 4 receptor antagonist that effectively reduces tumour-induced weight loss in a mouse model. J Med Chem 2004; 47: 1602-604.
13. Marks D. Personal communication, 2005.