Dominant-negative c-Jun inhibits rat cardiac hypertrophy induced by angiotensin II and hypertension

Gene Therapy

Volumn 13, Issue 4, 2006, Pages 348-355

  Kim Mitsuyama, S ^a   Izumi, Y ^b   Izumiya, Y ^b   Namba, M ^b   Yoshida, K ^b   Wake, R ^b   Yoshiyama, M ^b   Iwao, H ^b  

^a KUMAMOTO UNIVERSITY   (Japan)

^b OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Angiotensin II; AP 1; Cardiac hypertrophy; Dominant negative mutant; Gene expression; Hypertension

Indexed keywords

ADENOVIRUS VECTOR; ANGIOTENSIN II; BRAIN NATRIURETIC PEPTIDE; COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGEN TYPE 4; MONOCYTE CHEMOTACTIC PROTEIN 1; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN C JUN; S6 KINASE; TRANSCRIPTION FACTOR AP 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG TARGETING; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENE TRANSFER; GENETIC TRANSDUCTION; HEART VENTRICLE HYPERTROPHY; HYPERTENSION; IN VIVO STUDY; MALE; MUTANT; NONHUMAN; PRIORITY JOURNAL; RAT; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANGIOTENSIN II; ANIMALS; BLOTTING, WESTERN; CARDIOMEGALY; CHEMOKINE CCL2; COLLAGEN TYPE I; COLLAGEN TYPE III; COLLAGEN TYPE IV; GENE DELETION; GENE THERAPY; GENES, DOMINANT; GENETIC VECTORS; HYPERTENSION; INJECTIONS; MALE; MODELS, ANIMAL; NATRIURETIC PEPTIDE, BRAIN; PHOSPHORYLATION; PLASMINOGEN ACTIVATOR INHIBITOR 1; RATS; RATS, SPRAGUE-DAWLEY; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; TRANSCRIPTION FACTOR AP-1;

ADENOVIRIDAE; ANIMALIA;

EID: 32444442985     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3302670     Document Type: Article

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