Effect of surfactant deficiency and surfactant replacement on airway patency in the piglet lung

Respiratory Physiology and Neurobiology

Volumn 150, Issue 2-3, 2006, Pages 173-181

  Ellyett, Kevin M ^a   Cragg, Patricia A ^a   Broadbent, Roland S ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Airway patency; Hygroscopic surfactant replacement; Piglet; Surfactant deficiency

Indexed keywords

LUNG SURFACTANT;

AIRWAY OBSTRUCTION; ANIMAL TISSUE; ARTICLE; CANNULATION; CONTROLLED STUDY; GAS FLOW; LUNG DISEASE; LUNG INFLATION; LUNG LAVAGE; LUNG PRESSURE; NONHUMAN; PRIORITY JOURNAL; RAT; RESPIRATORY TRACT DISEASE;

AIRWAY RESISTANCE; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; IRRIGATION; LUNG; PULMONARY SURFACTANTS; SWINE;

EID: 32444435693     PISSN: 15699048     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.resp.2005.04.004     Document Type: Article

References (28)

1. Anon. The Vermont-Oxford Trials Network: very low birth weight outcomes for 1990. Investigators of the Vermont-Oxford Trials Network Database Project Pediatrics 91 1993 540 545
2. M. Arborelius Generation of a microaerosol suitable for deposition in the peripheral airways Eur. J. Respir. Dis. Suppl. 63 1982 19 27
3. K.M. Ellyett, R.S. Broadbent, E.R. Fawcett, and A.J. Campbell Surfactant aerosol treatment of respiratory distress syndrome in the spontaneously breathing premature rabbit Pediatr. Res. 39 1996 953 957
4. Ellyett, K.M., 1999. Exogenous surfactant aerosols for the treatment of neonatal respiratory distress syndrome: surfactant distribution patterns, effects on airway stability and cardiorespiratory function in piglets. Ph.D. Thesis. University of Otago, Dunedin, pp. 277.
5. G. Enhorning, and B.A. Holm Disruption of pulmonary surfactant's ability to maintain openness of a narrow tube J. Appl. Physiol. 74 1993 2922 2927
6. G. Enhorning, L.C. Duffy, and R.C. Welliver Pulmonary surfactant maintains patency of conducting airways in the rat Am. J. Respir. Crit. Care Med. 151 1995 554 556
7. G. Enhorning, A. Yarussi, P. Rao, and I. Vargas Increased airway resistance due to surfactant dysfunction can be alleviated with aerosol surfactant Can. J. Physiol. Pharmacol. 74 1996 687 691
8. D.P. Gaver, R.W. Samsel, and J. Solway Effects of surface tension and viscosity on airway reopening J. Appl. Physiol. 69 1990 74 85
9. I. Gonda Aerosol for delivery of theraputic and diagnostic agents to the respiratory tract Crit. Rev. Ther. Drug Carrier Syst. 6 1990 273 313
10. M. Griese Pulmonary surfactant in health and human lung diseases: state of the art Eur. Respir. J. 13 1999 1455 1476
11. H.L. Halliday Natural vs synthetic surfactants in neonatal respiratory distress syndrome Drugs 51 1996 226 237
12. D. Halpern, and J.B. Grotberg Surfactant effects on fluid-elastic instabilities of liquid-lined flexible tubes: a model of airway closure J. Biomech. Eng. 115 1993 271 277
13. D. Halpern, O.E. Jensen, and J.B. Grotberg A theoretical study of surfactant and liquid delivery into the lung J. Appl. Physiol. 85 1998 333 352
14. A.J. Hickey, and T.B. Martonen Behavior of hygroscopic pharmaceutical aerosols and the influence of hydrophobic additives Pharm. Res. 10 1993 1 7
15. J. Hohlfeld, H. Fabel, and H. Hamm The role of pulmonary surfactant in obstructive airways disease Eur. Respir. J. 10 1997 482 491
16. J.D. Horbar, L.L. Wright, R.F. Soll, E.C. Wright, A.A. Fanaroff, S.B. Korones, S. Shankaran, W. Oh, B.D. Fletcher, and C.R. Bauer A multicenter randomized trial comparing two surfactants for the treatment of neonatal respiratory distress syndrome. National Institute of Child Health and Human Development Neonatal Research Network J. Pediatr. 123 1993 757 766
17. N.N. Jarjour, and G. Enhorning Antigen-induced airway inflammation in atopic subjects generates dysfunction of pulmonary surfactant Am. J. Respir. Crit. Care Med. 160 1999 336 341
18. R.D. Kamm, and R.C. Schroter Is airway closure caused by a liquid film instability? Respir. Physiol. 75 1989 141 156
19. M. Liu, L. Wang, E. Li, and G. Enhorning Pulmonary surfactant will secure free airflow through a narrow tube J. Appl. Physiol. 71 1991 742 748
20. P.T. Macklem, D.F. Proctor, and J.C. Hogg The stability of peripheral airways Respir. Physiol. 8 1970 191 203
21. E.T. Naureckas, C.A. Dawson, B.S. Gerber, D.P.R. Gaver, H.L. Gerber, J.H. Linehan, J. Solway, and R.W. Samsel Airway reopening pressure in isolated rat lungs J. Appl. Physiol. 76 1994 1372 1377 (see comments)
22. D.R. Otis Jr., M. Johnson, T.J. Pedley, and R.D. Kamm Role of pulmonary surfactant in airway closure: a computational study J. Appl. Physiol. 75 1993 1323 1333
23. M.L. Perun, and D.P.R. Gaver Interaction between airway lining fluid forces and parenchymal tethering during pulmonary airway reopening J. Appl. Physiol. 79 1995 1717 1728
24. R.J. Rodriguez, and R.J. Martin Exogenous surfactant therapy in newborns Respir. Care Clin. N. Am. 5 1999 595 616
25. C. Rosen, W. Schecter, R. Mellins, and G. Haddad Effect of acute hypoxia on metabolism and ventilation in awake piglet Respir. Physiol. 91 1993 307 319
26. Z. Wang, S.B. Hall, and R.H. Notter Dynamic surface activity of films of lung surfactant phospholipids, hydrophobic proteins, and neutral lipids J. Lipid Res. 36 1995 1283 1293
27. D.Y. Yap, W.D. Liebkemann, J. Solway, and D.P. Gaver Influences of parenchymal tethering on the reopening of closed pulmonary airways J. Appl. Physiol. 76 1994 2095 2105
28. E.M. Zola, A.M. Overbach, J.H. Gunkel, B.R. Mitchell, B.T. Nagle, N.G. DeMarco, G.A. Henwood, and A.J. Gold Treatment Investigational New Drug experience with Survanta (beractant) Pediatrics 91 1993 546 551