Determination of the cyclic depsipeptide FK228, a histone deacetylase inhibitor, by liquid chromatography-mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 809, Issue 1, 2004, Pages 81-86

  Hwang, Kyunghwa ^a   Piekarz, Richard L ^a   Bates, Susan E ^a   Figg, William D ^a   Sparreboom, Alex ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Cyclic depsipeptide; FK228

Indexed keywords

CHEMICAL ANALYSIS; CONCENTRATION (PROCESS); ENZYME INHIBITION; ENZYMES; IONIZATION; PHARMACOKINETICS; TUMORS;

CYCLIC DEPSIPEPTIDES; HISTONE DEACETYLASE INHIBITORS;

CHROMATOGRAPHIC ANALYSIS;

AMMONIUM FORMATE; DEPSIPEPTIDE; FR 901228; HISTONE DEACETYLASE INHIBITOR; METHANOL;

ACCURACY; ANALYTIC METHOD; ARTICLE; CALIBRATION; CONCENTRATION (PARAMETERS); DRUG DETERMINATION; ELECTROSPRAY; HUMAN; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MASS SPECTROMETRY; PLASMA; PRIORITY JOURNAL; SAMPLE; SPECTROMETRY;

ANTIBIOTICS, ANTINEOPLASTIC; CALIBRATION; DEPSIPEPTIDES; ENZYME INHIBITORS; HISTONE DEACETYLASES; HUMANS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS;

EID: 3242885126     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2004.06.007     Document Type: Article

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