The molecular mechanism of enveloped virus-cell membrane fusion

Progress in Biochemistry and Biophysics

Volumn 31, Issue 6, 2004, Pages 482-491

  Wang, Xiao Jia ^a   Zhang, Gatherine W H ^b   Wang, Ming ^a   Gao, George F ^c  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b Oxagen Ltd   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Conformational change; Enveloped virus; Fusion

Indexed keywords

ENFUVIRTIDE; VIRUS FUSION PROTEIN; VIRUS GLYCOPROTEIN;

FLAVIVIRUS; HUMAN IMMUNODEFICIENCY VIRUS; INFLUENZA VIRUS; MEMBRANE FUSION; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTOR BINDING; REVIEW; VIRUS ENVELOPE; VIRUS INFECTION;

FLAVIVIRUS; HUMAN IMMUNODEFICIENCY VIRUS; INFLUENZA VIRUS;

EID: 3242789415     PISSN: 10003282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (34)

1. Chazal N, Gerlier D. Virus entry, assembly, budding, and membrane rafts. Microbiol Mol Biol Rev, 2003, 67 (2): 226-237
2. Mousavi S A, Malerod L, Berg T, et al. Clathrin-dependent endocytosis. Biochem J, 2004, 377 (Pt 1): 1-16
3. Skehel J J, Wiley D C. Coiled coils in both intracellular vesicle and viral membrane fusion. Cell, 1998, 95 (7): 871-874
4. Lamb R A, Joshi S B, Dutch R E. The paramyxovirus fusion protein forms an extremely stable core trimer: structural parallels to influenza virus haemagglutinin and HIV-1 gp41. Mol Membr Biol, 1999, 16 (1): 11-19
5. Weissenhorn W, Dessen A, Calder L J, et al. Structural basis for membrane fusion by enveloped viruses. Mol Membr Biol, 1999, 16 (1): 3-9
6. Skehel J J, Wiley D C. Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin. Annu Rev Biochem, 2000, 69: 531-569
7. Bentz J. Membrane fusion mediated by coiled coils: a hypothesis. Biophys J, 2000, 78 (2): 886-900
8. Eckert D M, Kim P S. Mechanisms of viral membrane fusion and its inhibition. Annu Rev Biochem, 2001, 70: 777-810
9. Colman P M, Lawrence M C. The structural biology of type I viral membrane fusion. Nat Rev Mol Cell Biol, 2003, 4 (4): 309-319
10. Wyatt R, Sodroski J. The HIV-1 envelope glycoproteins: fusogens, antigens, and immunogens. Science, 1998, 280 (5371): 1884-1888
11. Heinz F X, Allison S L. Structures and mechanisms in flavivirus fusion. Adv Virus Res, 2000, 55: 231-269
12. Heinz F X, Allison S L. The machinery for flavivirus fusion with host cell membranes. Curr Opin Microbiol, 2001, 4 (4): 450-455
13. Hernandez L D, Hoffman L R, Wolfsberg T G, et al. Virus-cell and cell-cell fusion. Annu Rev Cell Dev Biol, 1996, 12: 627-661
14. Wiley D C, Skehel J J. The structure and function of the hemagglutinin membrane glycoprotein of influenza virus. Annu Rev Biochem, 1987, 56: 365-394
15. Freed E O, Myers D J, Risser R. Characterization of the fusion domain of the human immunodeficiency virus type 1 envelope glycoprotein gp41. Proc Natl Acad Sci USA, 1990, 87 (12): 4650 -4654
16. Lamb R A. Paramyxovirus fusion: a hypothesis for changes. Virology, 1993, 197 (1): 1-11
17. Feldmann H, Volchkov V E, Volchkova V A, et al. The glycoproteins of Marburg and Ebola virus and their potential roles in pathogenesis. Arch Virol Suppl, 1999, 15: 159-169
18. Singh M, Berger B, Kim P S. LearnCoil-VMF: computational evidence for coiled-coil-like motifs in many viral membrane-fusion proteins. J Mol Biol, 1999, 290 (5): 1031-1041
19. Weissenhorn W, Dessen A, Harrison S C, et al. Atomic structure of the ectodomain from HIV-1 gp41. Nature, 1997, 387 (6631): 426-430
20. Chan D C, Fass D, Berger J M, et al. Core structure of gp41 from the HIV envelope glycoprotein. Cell, 1997, 89 (2): 263-273
21. Lu M, Blacklow S C, Kim PS. A trimeric structural domain of the HIV-1 transmembrane glycoprotein. Nat Struct Biol, 1995, 2 (12): 1075-1082
22. Yu M, Wang E, Liu Y, et al. Six-helix bundle assembly and characterization of heptad repeat regions from the F protein of Newcastle disease virus. J Gen Virol, 2002, 83 (Pt 3): 623-629
23. Zhu J, Zhang C W H, Qi Y, et al. The fusion protein core of measles virus forms stable coiled-coil trimer. Biochem Biophys Res Commun, 2002, 299 (5): 897-902
24. Zhu J Q, Zhang C W H, Rao Z, et al. Biochemical and biophysical analysis of heptad repeat regions from the fusion protein of Menangle virus, a newly emergent paramyxovirus. Arch Virol, 2003, 148 (7): 1301-1316
25. Wang E, Sun X, Qian Y, et al. Both heptad repeats of human respiratory syncytial virus fusion protein are potent inhibitors of viral fusion. Biochem Biophys Res Commun, 2003, 302 (3): 469-475
26. Chen J, Lee K H, Steinhauer D A, et al. Structure of the hemagglutinin precursor cleavage site, a determinant of influenza pathogenicity and the origin of the labile conformation. Cell, 1998, 95 (3): 409-417
27. Fackler O T, Peterlin B M. Endocytic entry of HIV-1. Curr Biol, 2000, 10 (16): 1005-1008
28. Saez-Cirion A, Nieva J L. Conformational transitions of membrane-bound HIV-1 fusion peptide. Biochim Biophys Acta, 2002, 1564 (1): 57-65
29. Carr C M, Kim P S. A spring-loaded mechanism for the conformational change of influenza hemagglutinin. Cell, 1993, 73 (4): 823-832
30. Wilson I A, Skehel J J, Wiley D C. Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolution. Nature, 1981, 289 (5796): 366-373
31. Bullough P A, Hughson F M, Skehel J J, et al. Structure of influenza haemagglutinin at the pH of membrane fusion. Nature, 1994, 371 (6492): 37-43
32. Muller M, Katsov K, Schick M. A new mechanism of model membrane fusion determined from Monte Carlo simulation. Biophys J, 2003, 85 (3): 1611-1623
33. Bosch B J, van der Zee R, de Haan C A, et al. The coronavirus spike protein is a class I virus fusion protein: structural and functional characterization of the fusion core complex. J Virol, 2003, 77 (16): 8801-8811
34. Cuzin L, Alvarez M. Enfuvirtide for prophylaxis against HIV infection. N Engl J Med, 2003, 349 (22): 2169-2170