Enzymatic resolution of chiral phosphinate esters

Journal of the American Chemical Society

Volumn 126, Issue 29, 2004, Pages 8888-8889

  Li, Yingchun ^a   Aubert, Sarah D ^a   Maes, Eugene G ^a   Raushel, Frank M ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTER; METHYLPHENYLPHOSPHINATE; PHOSPHINATE ESTER; PHOSPHINE DERIVATIVE; PHOSPHOTRIESTERASE; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE; HYDROLYSIS; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; X RAY ANALYSIS; X RAY CRYSTALLOGRAPHY;

ESTERS; PHOSPHINIC ACIDS; PHOSPHORIC TRIESTER HYDROLASES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 3242786362     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja048457m     Document Type: Article

References (11)

1. (a) Raushel, F. M. Curr. Opin. Microbiol. 2002, 5, 288-295.
2. (b) Raushel, F. M.; Holden, H. M. Adv. Enzymol. Relat. Areas Mol. Biol. 2000, 74, 51-93.
3. Benning, M. M.; Shim, H.; Raushel, F. M.; Holden, H. M. Biochemistry 2001, 40, 2712-2722.
4. (a) Li, Y.; Aubert, S. D.; Raushel, F. M. J. Am. Chem. Soc. 2003, 125, 7526-7527.
5. (b) Li, W.; Li, Y.; Hill, C. M.; Lum, K. T.; Raushel, F. M. J. Am. Chem. Soc. 2002, 124, 3498-3499.
6. (c) Wu, F.; Li, W.-S.; Chen-Goodspeed, M.; Sogorb, M. A.; Raushel. F. M. J. Am. Chem. Soc. 2000, 122, 10206-10207.
7. Chen-Goodspeed, M.; Sogorb, M. A.; Wu, F.; Raushel, F. M. Biochemistry 2001, 40, 1325-1331.
8. Chen-Goodspeed, M.; Sogorb, M. A.; Wu, F.; Raushel, F. M. Biochemistry 2001, 40, 1332-1339.
9. Pietrusiewicz, K.; Zablocka, M. Chem. Rev. 1994, 94, 1375-1411.
10. Li, W.-S.; Lum, K. T.; Chen-Goodspeed, M.; Sogorb, M. A.; Raushel. F. M.; Bioorg. Med. Chem. 2001, 9, 2083-2091.
11. McEwen, W. E. In Topics in Phosphorus Chemistry; Grayson, M., Griffith, E. J., Eds.; Stereochemistry of Reactions of Organophosphorus Compounds, Vol. 2; Wiley-Interscience: New York, 1965; pp 1-44.