T cell immunity to type II collagen in the biobreeding rat: The identification and characterization of RT1u-restricted T cell epitopes on α1(II)

Journal of Immunology

Volumn 173, Issue 3, 2004, Pages 1795-1801

  Cremer, Michael A ^a,b   Ye, Xiu J ^a   Myers, Linda K ^a   Brand, David D ^a   Rosloniec, Edward F ^a   Kang, Andrew H ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; COLLAGEN TYPE 2; EPITOPE; HLA DR1 ANTIGEN; HLA DR4 ANTIGEN; ISOLEUCINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; OLIGOPEPTIDE; PROLINE;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; FEMALE; INGUINAL LYMPH NODE; LYMPHOCYTE PROLIFERATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; RAT; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TRANSGENIC MOUSE;

EID: 3242783930     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.173.3.1795     Document Type: Article

References (36)

1. Trentham, D. E., A. S. Townes, and A. H. Kang. 1977. Autoimmunity to type II collagen an experimental model of arthritis. J. Exp. Med. 146:857.
2. Courtenay, J. S., M. J. Dallman, A. D. Dayan, A. Martin, and B. Mosedale. 1980. Immunization against heterologous type II collagen induces arthritis in mice. Nature 283:666.
3. Cathcart, E. S., K. C. Hayes, W. A. Gonnerman, A. A. Lazzari, and C. Franzblau. 1986. Experimental arthritis in a nonhuman primate. I. Induction by bovine type II collagen. Lab. Invest. 54:26.
4. Watson, W. C., R. E. Tooms, P. G. Carnesale, and J. P. Dutkowsky. 1994. A case of germinal center formation by CD45RO T and CD20 B lymphocytes in rheumatoid arthritic subchondral bone: proposal for a two-compartment model of immune-mediated disease with implications for immunotherapeutic strategies. Clin. Immunol. Immunopathol. 73:27.
5. Wooley, P. H., H. S. Luthra, J. M. Stuart, and C. S. David. 1981. Type II collagen-induced arthritis in mice. I. Major histocompatibility complex (I region) linkage and antibody correlates. J. Exp. Med. 154:688.
6. Griffiths, M. M., and C. W. DeWitt. 1984. Genetic control of collagen-induced arthritis in rats: the immune response to type II collagen among susceptible and resistant strains and evidence for multiple gene control. J. Immunol. 132:2830.
7. Griffiths, M. M., and G. W. Cannon. 1993. Background genes confer protection against homologous rat type II collagen-induced arthritis in ACI (RT1a) rats. Transplant. Proc. 25:2829.
8. Griffiths, M. M., M. A. Cremer, D. S. Harper, S. McCall, and G. W. Cannon. 1992. Immunogenetics of collagen-induced arthritis in rats: both MHC and non-MHC gene products determine the epitope specificity of immune response to bovine and chick type II collagens. J. Immunol. 149:309.
9. Rosloniec, E. F., D. D. Brand, L. K. Myers, K. B. Whittington, M. Gumanovskaya, D. M. Zaller, A. Woods, D. M. Altmann, J. M. Stuart, and A. H. Kang. 1997, An HLA-DR1 transgene confers susceptibility to collagen-induced arthritis elicited with human type II collagen. J. Exp. Med. 185:1113.
10. Stuart, J. M., M. A. Cremer, A. S. Townes, and A. H. Kang. 1982. Type II collagen-induced arthritis in rats: passive transfer with serum and evidence that IgG anticollagen antibodies can cause arthritis. J. Exp. Med. 155:1.
11. Terato, K., K. A. Hasty, R. A. Reife, M. A. Cremer, A. H. Kang, and J. M. Stuart. 1992. Induction of arthritis with monoclonal antibodies to collagen. J. Immunol. 148:2103.
12. Takagishi, K., N. Kaibara, T. Hotokebuchi, C. Arita, M. Morinaga, and K. Arai. 1985. Serum transfer of collagen arthritis in congenitally athymic nude rats. J. Immunol. 134:3864.
13. Griffiths, M. M., E. J. Eichwald, J. H. Martin, C. B. Smith, and C. W. DeWitt. 1981. Immunogenetic control of experimental type II collagen-induced arthritis. I. Susceptibility and resistance among inbred strains of rats. Arthritis Rheum. 24:781.
14. Cremer, M. A., M. M. Griffiths, K. Terato, and A. H. Kang. 1995. Type XI and II collagen-induced arthritis in rats: characterization of inbred strains of rats for arthritis-susceptibility and immune-responsiveness to type XI and II collagen. Autoimmunity 20:153.
15. Watson, W. C., J. P. Thompson, K. Terato, M. A. Cremer, and A. H. Kang. 1990. Human HLA-DR β gene hypervariable region homology in the biobreeding BB rat: selection of the diabetic-resistant subline as a rheumatoid arthritis research tool to characterize the immunopathologic response to human type II collagen. J. Exp. Med. 172:1331.
16. Weyand, C. M., and J. J. Goronzy. 1997. The molecular basis of rheumatoid arthritis. J. Mol. Med. 75:772.
17. Rosloniec, E. F., A. H. Kang, L. K. Myers, and M. A. Cremer. 1996. Collagen-induced arthritis. In Current Protocols in Immunology. R. Coico and E. Shevach, eds. Weily & Sons, New York, p. 15.5.1.
18. Myers, L. K., K. Terato, J. M. Seyer, J. M. Stuart, and A. H. Kang. 1992. Characterization of a tolerogenic T cell epitope of type II collagen and its relevance to collagen-induced arthritis. J. Immunol. 149:1439.
19. Ala-Kokko, L., and D. J. Prockop. 1990. Completion of the intron-exon structure of the gene for human type II procollagen (COL2A1): variations in the nucleotide sequences of the alleles from three chromosomes. Genomics 8:454.
20. Michaelsson, E., V. Malmstrom, S. Reis, A. Engstrom, H. Burkhardt, and R. Holmdahl. 1994. T cell recognition of carbohydrates on type II collagen. J. Exp. Med. 180:745.
21. Urabe, K., H. J. Kim, G. Sarkar, J. T. Bronk, and M. E. Bolander. 2003. Determination of the complete cDNA sequence of rat type II collagen and evaluation of distinct expression patterns of types IIA and IIB procollagen mRNAs during fracture repair in rats. J. Orthop. Sci. 8:585.
22. Cremer, M. A., X. J. Ye, K. Terato, S. W. Owens, J. M. Seyer, and A. H. Kang. 1994. Type XI collagen-induced arthritis in the Lewis rat: characterization of cellular and humoral immune responses to native types XI, V, and II collagen and constituent α-chains. J. Immunol. 153:824.
23. Rosloniec, E. F., K. B. Whittington, D. D. Brand, L. K. Myers, and J. M. Stuart. 1996. Identification of MHC class II and TCR binding residues in the type II collagen immunodominant determinant mediating collagen-induced arthritis. Cell. Immunol. 172:21.
24. Rosloniec, E. F., D. D. Brand, L. K. Myers, Y. Esaki, K. B. Whittington, D. M. Zaller, A. Woods, J. M. Stuart, and A. H. Kang. 1998. Induction of autoimmune arthritis in HLA-DR4 (DRB1*0401) transgenic mice by immunization with human and bovine type II collagen. J. Immunol. 160:2573.
25. Ku, G., M. Kronenberg, D. J. Peacock, P. Tempst, M. L. Banquerigo, B. S. Braun, J. R. Reeve, Jr., and E. Brahn. 1993. Prevention of experimental autoimmune arthritis with a peptide fragment of type II collagen. Eur. J. Immunol. 23:591.
26. Brand, D. D., L. K. Myers, K. Terato, K. B. Whittington, J. M. Stuart, A. H. Kang, and E. F. Rosloniec. 1994. Characterization of the T cell determinants in the induction of autoimmune arthritis by bovine α 1(II)-CB11 in H-2q mice. J. Immunol. 152:3088.
27. Kjellen, P., U. Brunsberg, J. Broddefalk, B. Hansen, M. Vestberg, I. Ivarsson, A. Engstrom, A. Svejgaard, J. Kihlberg, L. Fugger, and R. Holmdahl. 1998. The structural basis of MHC control of collagen-induced arthritis; binding of the immunodominant type II collagen 256-270 glycopeptide to H-2Aq and H-2Ap molecules. Eur. J. Immunol. 28:755.
28. Vossenaar, E. R., S. Nijenhuis, M. M. Helsen, A. van der Heijden, T. Senshu, W. B. van den Berg, W. J. van Venrooij, and L. A. Joosten. 2003. Citrullination of synovial proteins in murine models of rheumatoid arthritis. Arthritis Rheum. 48:2489.
29. Sercarz, E. E., and E. Maverakis. 2003. MHC-guided processing: binding of large antigen fragments. Nat. Rev. Immunol. 3:621.
30. Seyer, J. M., K. A. Hasty, and A. H. Kang. 1989. Covalent structure of collagen: amino acid sequence of an arthritogenic cyanogen bromide peptide from type II collagen of bovine cartilage. Eur. J. Biochem. 181:159.
31. Kim, O.-H., L. J. Santell, Q. A. Shakey, M. Kreschmer, E. W. Kuhn, W. B. Upholt, W. Fowler, and C. E. Costello. 1998. ESI MS and MALDI-TOF MS confirmation of the primary structure and determination of posttranslational modifications of chicken type II collagen. In Proceedings of 46th American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topic. p. 236.
32. Myers, L. K., J. M. Seyer, J. M. Stuart, K. Terato, C. S. David, and A. H. Kang. 1993. T cell epitopes of type II collagen that regulate murine collagen-induced arthritis. J. Immunol. 151:500.
33. Myers, L. K., E. F. Rosloniec, J. M. Seyer, J. M. Stuart, and A. H. Kang. 1993. A synthetic peptide analogue of a determinant of type II collagen prevents the onset of collagen-induced arthritis. J. Immunol. 150:4652.
34. Rosloniec, E. F., K. B. Whittington, D. M. Zaller, and A. H. Kang. 2002. HLA-DR1 (DRB1*0101) and DR4 (DRB1*0401) use the same anchor residues for binding an immunodominant peptide derived from human type II collagen. J. Immunol. 168:253.
35. Myers, L. K., H. Miyahara, K. Terato, J. M. Seyer, J. M. Stuart, and A. H. Kang. 1995. Collagen-induced arthritis in B10.RIII mice (H-2r): identification of an arthritogenic T-cell determinant. Immunology 84:509.
36. Miyahara, H., L. K. Myers, E. F. Rosloniec, D. D. Brand, J. M. Seyer, J. M. Stuart, and A. H. Kang. 1995. Identification and characterization of a major tolerogenic T-cell epitope of type II collagen that suppresses arthritis in B10.RIII mice. Immunology 86:110.