메뉴 건너뛰기




Volumn 64, Issue 14, 2004, Pages 1575-1596

Fondaparinux sodium: A review of its use in the prevention of venous thromboembolism following major orthopaedic surgery

Author keywords

Deep vein thrombosis; Fondaparinux sodium; Pharmacodynamics; Pharmacoeconomics; Pharmacokinetics; Pulmonary embolism; Therapeutic use; Venous thrombosis

Indexed keywords

ANTICOAGULANT AGENT; ENOXAPARIN; FONDAPARINUX; LOW MOLECULAR WEIGHT HEPARIN;

EID: 3242760719     PISSN: 00126667     EISSN: None     Source Type: Journal    
DOI: 10.2165/00003495-200464140-00005     Document Type: Review
Times cited : (39)

References (78)
  • 1
    • 0035133938 scopus 로고    scopus 로고
    • Prevention of venous thromboembolism
    • Geerts WH, Heit JA, Clagett GP, et al. Prevention of venous thromboembolism. Chest 2001; 119 (1 Suppl.): 132S-75S
    • (2001) Chest , vol.119 , Issue.1 SUPPL.
    • Geerts, W.H.1    Heit, J.A.2    Clagett, G.P.3
  • 2
    • 0037437117 scopus 로고    scopus 로고
    • Management of venous thromboembolism: Past, present, and future
    • Apr 14
    • Hyers TM. Management of venous thromboembolism: past, present, and future. Arch Intern Med 2003 Apr 14; 163 (7): 759-68
    • (2003) Arch Intern Med , vol.163 , Issue.7 , pp. 759-768
    • Hyers, T.M.1
  • 3
    • 0033781629 scopus 로고    scopus 로고
    • Proficient and cost-effective approaches for the prevention and treatment of venous thrombosis and thromboembolism
    • Sep
    • Bick RL. Proficient and cost-effective approaches for the prevention and treatment of venous thrombosis and thromboembolism. Drugs 2000 Sep; 60 (3): 575-95
    • (2000) Drugs , vol.60 , Issue.3 , pp. 575-595
    • Bick, R.L.1
  • 4
    • 18544385353 scopus 로고    scopus 로고
    • The synthetic pentasaccharide fondaparinux: First in the class of antithrombotic agents that selectively inhibit coagulation factor Xa
    • Petitou M, Duchaussoy P, Herbert J-M, et al. The synthetic pentasaccharide fondaparinux: first in the class of antithrombotic agents that selectively inhibit coagulation factor Xa. Semin Thromb Hemost 2002; 28 (4): 393-402
    • (2002) Semin Thromb Hemost , vol.28 , Issue.4 , pp. 393-402
    • Petitou, M.1    Duchaussoy, P.2    Herbert, J.-M.3
  • 5
    • 4644274868 scopus 로고    scopus 로고
    • A randomized double-blind study to compare the efficacy and safety of postoperative fondaparinux (Arixtra®) and preoperative dalteparin in the prevention of venous thromboembolism after high-risk abdominal surgery: The PEGASUS study
    • abstract no. 40. Nov
    • Agnelli G, Bergqvist D, Cohen A, et al. A randomized double-blind study to compare the efficacy and safety of postoperative fondaparinux (Arixtra®) and preoperative dalteparin in the prevention of venous thromboembolism after high-risk abdominal surgery: the PEGASUS study [abstract no. 40]. Blood 2003 Nov; 102(11 Pt 1): 15a
    • (2003) Blood , vol.102 , Issue.11 PART 1
    • Agnelli, G.1    Bergqvist, D.2    Cohen, A.3
  • 6
    • 3242797015 scopus 로고    scopus 로고
    • Fondaparinux for the prevention of VTE in acutely ill medical patients
    • abstract no. 42. Nov
    • Cohen AT, Davidson BL, Gallus AS, et al. Fondaparinux for the prevention of VTE in acutely ill medical patients [abstract no. 42]. Blood 2003 Nov; 102 (11 Pt 1): 15a
    • (2003) Blood , vol.102 , Issue.11 PART 1
    • Cohen, A.T.1    Davidson, B.L.2    Gallus, A.S.3
  • 7
    • 0142182561 scopus 로고    scopus 로고
    • Subcutaneous fondaparinux versus intravenous unfractionated heparin in the initial treatment of pulmonary embolism
    • Oct
    • The Matisse Investigators. Subcutaneous fondaparinux versus intravenous unfractionated heparin in the initial treatment of pulmonary embolism. N Engl J Med 2003 Oct; 349 (18): 1695-702
    • (2003) N Engl J Med , vol.349 , Issue.18 , pp. 1695-1702
  • 8
    • 2542424669 scopus 로고    scopus 로고
    • Fondaparinux or enoxaparin for the initial treatment of symptomatic deep venous thrombosis
    • Jun 1
    • Büller HR, Davidson BL, Decousus H, et al., for The Matisse Investigators. Fondaparinux or enoxaparin for the initial treatment of symptomatic deep venous thrombosis. Ann Intern Med 2004 Jun 1; 140 (11): 867-73
    • (2004) Ann Intern Med , vol.140 , Issue.11 , pp. 867-873
    • Büller, H.R.1    Davidson, B.L.2    Decousus, H.3
  • 9
    • 0034822182 scopus 로고    scopus 로고
    • A synthetic factor-Xa inhibitor (ORG31540/SR9017A) as an adjunct to fibrinolysis in acute myocardial infarction: The PENTALYSE study
    • Sep
    • Coussement PK, Bassand J-P, Convens C, et al. A synthetic factor-Xa inhibitor (ORG31540/SR9017A) as an adjunct to fibrinolysis in acute myocardial infarction: the PENTALYSE study. Eur Heart J 2001 Sep; 22 (18): 1716-24
    • (2001) Eur Heart J , vol.22 , Issue.18 , pp. 1716-1724
    • Coussement, P.K.1    Bassand, J.-P.2    Convens, C.3
  • 10
    • 0033033652 scopus 로고    scopus 로고
    • Efficacy of a synthetic pentasaccharide, a pure factor Xa inhibitor, as an antithrombotic agent: A pilot study in the setting of coronary angioplasty
    • Vuillemenot A, Schiele F, Meneveau N, et al. Efficacy of a synthetic pentasaccharide, a pure factor Xa inhibitor, as an antithrombotic agent: a pilot study in the setting of coronary angioplasty. Thromb Haemost 1999; 81 (2): 214-20
    • (1999) Thromb Haemost , vol.81 , Issue.2 , pp. 214-220
    • Vuillemenot, A.1    Schiele, F.2    Meneveau, N.3
  • 11
    • 0036330282 scopus 로고    scopus 로고
    • Fondaparinux sodium
    • Keam SJ, Goa KL. Fondaparinux sodium. Drugs 2002; 62 (11): 1673-85; discussion 1686-7
    • (2002) Drugs , vol.62 , Issue.11 , pp. 1673-1685
    • Keam, S.J.1    Goa, K.L.2
  • 12
    • 8544252429 scopus 로고    scopus 로고
    • SR 90107A/Org 31540, a novel anti-factor Xa antithrombotic agent
    • Herbert JM, Petitou M, Lormeau JC, et al. SR 90107A/Org 31540, a novel anti-factor Xa antithrombotic agent. Cardiovasc Drug Rev 1997; 15 (1): 1-26
    • (1997) Cardiovasc Drug Rev , vol.15 , Issue.1 , pp. 1-26
    • Herbert, J.M.1    Petitou, M.2    Lormeau, J.C.3
  • 13
    • 0030952743 scopus 로고    scopus 로고
    • Biochemical and pharmacologic rationale for the development of a synthetic heparin pentasaccharide
    • Walenga JM, Jeske WP, Bara L, et al. Biochemical and pharmacologic rationale for the development of a synthetic heparin pentasaccharide. Thromb Res 1997; 86 (1): 1-36
    • (1997) Thromb Res , vol.86 , Issue.1 , pp. 1-36
    • Walenga, J.M.1    Jeske, W.P.2    Bara, L.3
  • 14
    • 0001858198 scopus 로고    scopus 로고
    • Comparative mechanism of action and pharmacokinetics of pentasaccharide and LMW heparins
    • May 5-8; Porto
    • Samama MM, Bara L, Walenga J. Comparative mechanism of action and pharmacokinetics of pentasaccharide and LMW heparins. 16th International Congress on Thrombosis; 2000 May 5-8; Porto, 99-102
    • (2000) 16th International Congress on Thrombosis , pp. 99-102
    • Samama, M.M.1    Bara, L.2    Walenga, J.3
  • 16
    • 0024360749 scopus 로고
    • In vitro studies of the interaction of heparin, low molecular weight heparin and heparinoids with platelets
    • Messmore Jr HL, Griffin B, Fareed J, et al. In vitro studies of the interaction of heparin, low molecular weight heparin and heparinoids with platelets. Ann N Y Acad Sci 1989; 556: 217-31
    • (1989) Ann N Y Acad Sci , vol.556 , pp. 217-231
    • Messmore Jr., H.L.1    Griffin, B.2    Fareed, J.3
  • 17
    • 0029588344 scopus 로고
    • Pharmacokinetics and tolerance of the natural pentasaccharide (SR90107/ORG31540) with high affinity to antithrombin III in man
    • Boneu B, Necciari J, Cariou R, et al. Pharmacokinetics and tolerance of the natural pentasaccharide (SR90107/ORG31540) with high affinity to antithrombin III in man. Thromb Haemost 1995; 74 (6): 1468-73
    • (1995) Thromb Haemost , vol.74 , Issue.6 , pp. 1468-1473
    • Boneu, B.1    Necciari, J.2    Cariou, R.3
  • 18
    • 2642617786 scopus 로고    scopus 로고
    • Biochemical and pharmacological properties of SANORG 34006, a potent and long-acting synthetic pentasaccharide
    • Jun
    • Herbert JM, Hérault JP, Bernat A, et al. Biochemical and pharmacological properties of SANORG 34006, a potent and long-acting synthetic pentasaccharide. Blood 1998 Jun; 91 (11): 4197-205
    • (1998) Blood , vol.91 , Issue.11 , pp. 4197-4205
    • Herbert, J.M.1    Hérault, J.P.2    Bernat, A.3
  • 19
    • 0030969911 scopus 로고    scopus 로고
    • Synthesis and pharmacological properties of a close analogue of an antithrombotic pentasaccharide (SR 90107A/ORG 31540)
    • May 23
    • Petitou M, Duchaussoy P, Jaurand G, et al. Synthesis and pharmacological properties of a close analogue of an antithrombotic pentasaccharide (SR 90107A/ORG 31540). J Med Chem 1997 May 23; 40 (11): 1600-7
    • (1997) J Med Chem , vol.40 , Issue.11 , pp. 1600-1607
    • Petitou, M.1    Duchaussoy, P.2    Jaurand, G.3
  • 20
    • 0031034272 scopus 로고    scopus 로고
    • Determination of the anti-factor Xa activity of the synthetic pentasaccharide SR 90107A/ORG 31540 and of two structural analogues
    • Jan 1
    • Lormeau JC, Herault JP, Gaich C, et al. Determination of the anti-factor Xa activity of the synthetic pentasaccharide SR 90107A/ORG 31540 and of two structural analogues. Thromb Res 1997 Jan 1; 85 (1): 67-75
    • (1997) Thromb Res , vol.85 , Issue.1 , pp. 67-75
    • Lormeau, J.C.1    Herault, J.P.2    Gaich, C.3
  • 21
    • 0025324338 scopus 로고
    • The inhibition of intrinsic prothrombinase and its generation by heparin and four derivatives in prothrombin poor plasma
    • Bendetowicz AV, Bara L, Samama MM. The inhibition of intrinsic prothrombinase and its generation by heparin and four derivatives in prothrombin poor plasma. Thromb Res 1990; 58: 445-54
    • (1990) Thromb Res , vol.58 , pp. 445-454
    • Bendetowicz, A.V.1    Bara, L.2    Samama, M.M.3
  • 22
    • 2142812859 scopus 로고    scopus 로고
    • Factor Xa is highly protected from antithrombin-fondaparinux and antithrombin-enoxaparin when incorporated into the prothrombinase complex
    • Brufatto N, Ward A, Nesheim ME. Factor Xa is highly protected from antithrombin-fondaparinux and antithrombin-enoxaparin when incorporated into the prothrombinase complex. J Thromb Haemost 2003; 1: 1258-63
    • (2003) J Thromb Haemost , vol.1 , pp. 1258-1263
    • Brufatto, N.1    Ward, A.2    Nesheim, M.E.3
  • 23
    • 0029794151 scopus 로고    scopus 로고
    • Biochemical and pharmacological properties of SANORG 32701: Comparison with the 'synthetic pentasaccharide' (SR 90107/ORG 31540) and standard heparin
    • Herbert JM, Hérault JP, Bernat A, et al. Biochemical and pharmacological properties of SANORG 32701: comparison with the 'synthetic pentasaccharide' (SR 90107/ORG 31540) and standard heparin. Circ Res 1996; 79 (3): 590-600
    • (1996) Circ Res , vol.79 , Issue.3 , pp. 590-600
    • Herbert, J.M.1    Hérault, J.P.2    Bernat, A.3
  • 24
    • 0023214250 scopus 로고
    • Antithrombotic activity of a synthetic heparin pentasaccharide in a rabbit stasis thrombosis model using different thrombogenic challenges
    • Walenga JM, Petitou M, Lormeau JC, et al. Antithrombotic activity of a synthetic heparin pentasaccharide in a rabbit stasis thrombosis model using different thrombogenic challenges. Thromb Res 1987; 46: 187-98
    • (1987) Thromb Res , vol.46 , pp. 187-198
    • Walenga, J.M.1    Petitou, M.2    Lormeau, J.C.3
  • 25
    • 0028006821 scopus 로고
    • Pharmacokinetic and antithrombotic properties of two pentasaccharides with high affinity to antithrombin III in the rabbit: Comparison with CY216
    • Carrie D, Caranobe C, Saivin S, et al. Pharmacokinetic and antithrombotic properties of two pentasaccharides with high affinity to antithrombin III in the rabbit: comparison with CY216. Blood 1994; 84 (8): 2571-7
    • (1994) Blood , vol.84 , Issue.8 , pp. 2571-2577
    • Carrie, D.1    Caranobe, C.2    Saivin, S.3
  • 26
    • 0030035480 scopus 로고    scopus 로고
    • Antithrombin-mediated inhibition of factor VIIa-tissue factor complex by the synthetic pentasaccharide representing the heparin binding site to antithrombin
    • Jul
    • Lormeau JC, Herault JP, Herbert JM. Antithrombin-mediated inhibition of factor VIIa-tissue factor complex by the synthetic pentasaccharide representing the heparin binding site to antithrombin. Thromb Haemost 1996 Jul; 76 (1): 5-8
    • (1996) Thromb Haemost , vol.76 , Issue.1 , pp. 5-8
    • Lormeau, J.C.1    Herault, J.P.2    Herbert, J.M.3
  • 27
    • 0031797682 scopus 로고    scopus 로고
    • Comparative effects of synthetic pentasaccharide, low-molecular-weight heparin, unfractionated heparin and recombinant hirudin on the generation of factor VIIa and prothrombin activation after coagulation of human plasma
    • Gerotziafas GT, Bara L, Bloch MF, et al. Comparative effects of synthetic pentasaccharide, low-molecular-weight heparin, unfractionated heparin and recombinant hirudin on the generation of factor VIIa and prothrombin activation after coagulation of human plasma. Blood Coagul Fibrinolysis 1998; 9 (7): 571-80
    • (1998) Blood Coagul Fibrinolysis , vol.9 , Issue.7 , pp. 571-580
    • Gerotziafas, G.T.1    Bara, L.2    Bloch, M.F.3
  • 28
    • 0025082538 scopus 로고
    • Heparin-stimulated inhibition of factor IXa generation and factor IXa neutralization in plasma
    • Aug 1
    • Pieters J, Lindhout T, Willems G. Heparin-stimulated inhibition of factor IXa generation and factor IXa neutralization in plasma. Blood 1990 Aug 1; 76 (3): 549-54
    • (1990) Blood , vol.76 , Issue.3 , pp. 549-554
    • Pieters, J.1    Lindhout, T.2    Willems, G.3
  • 29
    • 0041315481 scopus 로고    scopus 로고
    • Mechanism of catalysis of inhibition of factor IXa by antithrombin in the presence of heparin or pentasaccharide
    • Sep 12
    • Wiebe EM, Stafford AR, Fredenburgh JC, et al. Mechanism of catalysis of inhibition of factor IXa by antithrombin in the presence of heparin or pentasaccharide. J Biol Chem 2003 Sep 12; 278 (37): 35767-74
    • (2003) J Biol Chem , vol.278 , Issue.37 , pp. 35767-35774
    • Wiebe, E.M.1    Stafford, A.R.2    Fredenburgh, J.C.3
  • 30
    • 0023792171 scopus 로고
    • a by antithrombin III/heparin during factor X activation
    • Oct 25
    • a by antithrombin III/heparin during factor X activation. J Biol Chem 1988 Oct 25; 263 (30): 15313-8
    • (1988) J Biol Chem , vol.263 , Issue.30 , pp. 15313-15318
    • Pieters, J.1    Willems, G.2    Hemker, H.C.3
  • 31
    • 0036714851 scopus 로고    scopus 로고
    • The structure of synthetic oligosaccharides in relation to factor IXa inhibition
    • Hérault JP, Gaich C, Bono F, et al. The structure of synthetic oligosaccharides in relation to factor IXa inhibition. Thromb Haemost 2002; 88 (3): 432-5
    • (2002) Thromb Haemost , vol.88 , Issue.3 , pp. 432-435
    • Hérault, J.P.1    Gaich, C.2    Bono, F.3
  • 32
    • 0029563321 scopus 로고
    • The effect of the synthetic pentasaccharide SR 90107/ORG 31540 on thrombin generation ex vivo is uniquely due to ATIII-mediated neutralization of factor Xa
    • Lormeau JC, Herault JP. The effect of the synthetic pentasaccharide SR 90107/ORG 31540 on thrombin generation ex vivo is uniquely due to ATIII-mediated neutralization of factor Xa. Thromb Haemost 1995; 74 (6): 1474-7
    • (1995) Thromb Haemost , vol.74 , Issue.6 , pp. 1474-1477
    • Lormeau, J.C.1    Herault, J.P.2
  • 33
    • 0025255513 scopus 로고
    • The effect of molecular weight on heparin binding to platelets
    • Horne 3rd MK, Chao ES. The effect of molecular weight on heparin binding to platelets. Br J Haematol 1990; 74 (3): 306-12
    • (1990) Br J Haematol , vol.74 , Issue.3 , pp. 306-312
    • Horne III, M.K.1    Chao, E.S.2
  • 34
    • 0030980765 scopus 로고    scopus 로고
    • Absence of cross-reactivity of SR90107A/ORG31540 pentasaccharide with antibodies to heparin-PF4 complexes developed in heparin-induced thrombocytopenia
    • Amiral J, Lormeau JC, Marfaing-Koka A, et al. Absence of cross-reactivity of SR90107A/ORG31540 pentasaccharide with antibodies to heparin-PF4 complexes developed in heparin-induced thrombocytopenia. Blood Coagul Fibrinolysis 1997; 8 (2): 114-7
    • (1997) Blood Coagul Fibrinolysis , vol.8 , Issue.2 , pp. 114-117
    • Amiral, J.1    Lormeau, J.C.2    Marfaing-Koka, A.3
  • 35
    • 3242745562 scopus 로고    scopus 로고
    • Effect of fondaparinux on platelet activation in the presence of heparin-dependent anti-platelet antibodies. A blinded comparative multicenter study with unfractionated heparin
    • abstract no. 1145. Nov
    • Savi P, Chong B, Greinacher A, et al. Effect of fondaparinux on platelet activation in the presence of heparin-dependent anti-platelet antibodies. A blinded comparative multicenter study with unfractionated heparin [abstract no. 1145]. Blood 2003 Nov; 102 (11 Pt 1): 319a
    • (2003) Blood , vol.102 , Issue.11 PART 1
    • Savi, P.1    Chong, B.2    Greinacher, A.3
  • 36
    • 0032755968 scopus 로고    scopus 로고
    • Synthetic pentasaccharides do not cause platelet activation by antiheparin-platelet factor 4 antibodies
    • Ahmad S, Jeske WP, Walenga JM, et al. Synthetic pentasaccharides do not cause platelet activation by antiheparin-platelet factor 4 antibodies. Clin App Thromb Hemost 1999; 5 (4): 259-66
    • (1999) Clin App Thromb Hemost , vol.5 , Issue.4 , pp. 259-266
    • Ahmad, S.1    Jeske, W.P.2    Walenga, J.M.3
  • 37
    • 0002970153 scopus 로고
    • Relative contribution of factor Xa and factor IIa. Inhibition in the mediation of the antithrombotic actions of LMWHs and synthetic heparin pentasaccharides
    • Walenga JM, Fareed J. Relative contribution of factor Xa and factor IIa. Inhibition in the mediation of the antithrombotic actions of LMWHs and synthetic heparin pentasaccharides. Thromb Haemorrh Disord 1991; 3 (2): 53-9
    • (1991) Thromb Haemorrh Disord , vol.3 , Issue.2 , pp. 53-59
    • Walenga, J.M.1    Fareed, J.2
  • 38
    • 0041831051 scopus 로고    scopus 로고
    • Efficacy of pentasaccharide on a prethrombosis model based on a calibrated stasis by the increase in up-stream venous pressure
    • Pottier P, Planchon B, Truchaud F, et al. Efficacy of pentasaccharide on a prethrombosis model based on a calibrated stasis by the increase in up-stream venous pressure. Blood Coagul Fibrinolysis 2003; 14 (6): 587-91
    • (2003) Blood Coagul Fibrinolysis , vol.14 , Issue.6 , pp. 587-591
    • Pottier, P.1    Planchon, B.2    Truchaud, F.3
  • 39
    • 3242742510 scopus 로고    scopus 로고
    • Neutralization of the anticoagulant effect of a synthetic heparinomimetic (pentasaccharide) by heparinase I: Potential clinical implications
    • abstract no. P2246. Jul 6-12; Paris
    • Iqbal O, Silver P, Walenga JM, et al. Neutralization of the anticoagulant effect of a synthetic heparinomimetic (pentasaccharide) by heparinase I: potential clinical implications [abstract no. P2246]. 18th Congress of the International Society on Thrombosis and Haemostasis; 2001 Jul 6-12; Paris
    • (2001) 18th Congress of the International Society on Thrombosis and Haemostasis
    • Iqbal, O.1    Silver, P.2    Walenga, J.M.3
  • 40
    • 0037069334 scopus 로고    scopus 로고
    • Ability of recombinant factor VIIa to reverse the anticoagulant effect of the pentasaccharide fondaparinux in healthy volunteers
    • Bijsterveld NR, Moons AH, Boekholdt SM, et al. Ability of recombinant factor VIIa to reverse the anticoagulant effect of the pentasaccharide fondaparinux in healthy volunteers. Circulation 2002; 106 (20): 2550-4
    • (2002) Circulation , vol.106 , Issue.20 , pp. 2550-2554
    • Bijsterveld, N.R.1    Moons, A.H.2    Boekholdt, S.M.3
  • 41
    • 0036395978 scopus 로고    scopus 로고
    • The pharmacokinetics of fondaparinux sodium in healthy volunteers
    • Donat F, Duret JP, Santoni A, et al. The pharmacokinetics of fondaparinux sodium in healthy volunteers. Clin Pharmacokinet 2002; 41 Suppl. 2: 1-9
    • (2002) Clin Pharmacokinet , vol.41 , Issue.2 SUPPL. , pp. 1-9
    • Donat, F.1    Duret, J.P.2    Santoni, A.3
  • 42
    • 0036397702 scopus 로고    scopus 로고
    • Absence of interaction of fondaparinux sodium with aspirin and piroxicam in healthy male volunteers
    • Ollier C, Faaij RA, Santoni A, et al. Absence of interaction of fondaparinux sodium with aspirin and piroxicam in healthy male volunteers. Clin Pharmacokinet 2002; 41 Suppl. 2: 31-7
    • (2002) Clin Pharmacokinet , vol.41 , Issue.2 SUPPL. , pp. 31-37
    • Ollier, C.1    Faaij, R.A.2    Santoni, A.3
  • 43
    • 0036380990 scopus 로고    scopus 로고
    • Absence of an interaction between the synthetic pentasaccharide fondaparinux and oral warfarin
    • Faaij RA, Burggraaf J, Schoemaker RC, et al. Absence of an interaction between the synthetic pentasaccharide fondaparinux and oral warfarin. Br J Clin Pharmacol 2002; 54 (3): 304-8
    • (2002) Br J Clin Pharmacol , vol.54 , Issue.3 , pp. 304-308
    • Faaij, R.A.1    Burggraaf, J.2    Schoemaker, R.C.3
  • 44
    • 0036394274 scopus 로고    scopus 로고
    • Absence of interaction of fondaparinux sodium with digoxin in healthy volunteers
    • Mant T, Fournié P, Ollier C, et al. Absence of interaction of fondaparinux sodium with digoxin in healthy volunteers. Clin Pharmacokinet 2002; 41 Suppl. 2: 39-45
    • (2002) Clin Pharmacokinet , vol.41 , Issue.2 SUPPL. , pp. 39-45
    • Mant, T.1    Fournié, P.2    Ollier, C.3
  • 45
    • 0036396028 scopus 로고    scopus 로고
    • Fondaparinux sodium mechanism of action: Identification of specific binding to purified and human plasma-derived proteins
    • Paolucci F, Claviés MC, Donat F, et al. Fondaparinux sodium mechanism of action: identification of specific binding to purified and human plasma-derived proteins. Clin Pharmacokinet 2002; 41 Suppl. 2: 11-8
    • (2002) Clin Pharmacokinet , vol.41 , Issue.2 SUPPL. , pp. 11-18
    • Paolucci, F.1    Claviés, M.C.2    Donat, F.3
  • 46
    • 0036253181 scopus 로고    scopus 로고
    • Absence of placental transfer of pentasaccharide (fondaparinux, Arixtra®) in the dually perfused human cotyledon in vitro
    • Lagrange F, Vergnes C, Brun JL, et al. Absence of placental transfer of pentasaccharide (fondaparinux, Arixtra®) in the dually perfused human cotyledon in vitro. Thromb Haemost 2002; 87 (5): 831-5
    • (2002) Thromb Haemost , vol.87 , Issue.5 , pp. 831-835
    • Lagrange, F.1    Vergnes, C.2    Brun, J.L.3
  • 47
    • 0036394531 scopus 로고    scopus 로고
    • Fondaparinux sodium is not metabolised in mammalian liver fractions and does not inhibit cytochrome P450-mediated metabolism of concomitant drugs
    • Lieu C, Shi J, Donat F, et al. Fondaparinux sodium is not metabolised in mammalian liver fractions and does not inhibit cytochrome P450-mediated metabolism of concomitant drugs. Clin Pharmacokinet 2002; 41 Suppl. 2: 19-26
    • (2002) Clin Pharmacokinet , vol.41 , Issue.2 SUPPL. , pp. 19-26
    • Lieu, C.1    Shi, J.2    Donat, F.3
  • 48
    • 0037129742 scopus 로고    scopus 로고
    • Postoperative fondaparinux versus preoperative enoxaparin for prevention of venous thromboembolism in elective hip-replacement surgery: A randomised double-blind comparison
    • May 18
    • Lassen MR, Bauer KA, Eriksson BI, et al., for the European Pentasaccharide Hip Elective Surgery Study (EPHESUS) Steering Committee. Postoperative fondaparinux versus preoperative enoxaparin for prevention of venous thromboembolism in elective hip-replacement surgery: a randomised double-blind comparison. Lancet 2002 May 18; 359: 1715-20
    • (2002) Lancet , vol.359 , pp. 1715-1720
    • Lassen, M.R.1    Bauer, K.A.2    Eriksson, B.I.3
  • 49
    • 0037129720 scopus 로고    scopus 로고
    • Postoperative fondaparinux versus postoperative enoxaparin for prevention of venous thromboembolism after elective hip-replacement surgery: A randomised double-blind trial
    • May 18
    • Turpie AGG, Bauer KA, Eriksson BI, et al., for the PENTATHLON 2000 Study Steering Committee. Postoperative fondaparinux versus postoperative enoxaparin for prevention of venous thromboembolism after elective hip-replacement surgery: a randomised double-blind trial. Lancet 2002 May 18; 359: 1721-6
    • (2002) Lancet , vol.359 , pp. 1721-1726
    • Agg, T.1    Bauer, K.A.2    Eriksson, B.I.3
  • 50
    • 0035522304 scopus 로고    scopus 로고
    • Fondaparinux compared with enoxaparin for the prevention of venous thromboembolism after elective major knee surgery
    • Nov
    • Bauer KA, Eriksson BI, Lassen MR, et al., for the Steering Committee of the Pentasaccharide in Major Knee Surgery Study. Fondaparinux compared with enoxaparin for the prevention of venous thromboembolism after elective major knee surgery. N Engl J Med 2001 Nov; 345 (18): 1305-10
    • (2001) N Engl J Med , vol.345 , Issue.18 , pp. 1305-1310
    • Bauer, K.A.1    Eriksson, B.I.2    Lassen, M.R.3
  • 51
    • 0035522302 scopus 로고    scopus 로고
    • Fondaparinux compared with enoxaparin for the prevention of venous thromboembolism after hip-fracture surgery
    • Nov
    • Eriksson BI, Bauer KA, Lassen MR, et al., for the Steering Committee of the Pentasaccharide in Hip-Fracture Surgery Study. Fondaparinux compared with enoxaparin for the prevention of venous thromboembolism after hip-fracture surgery. N Engl J Med 2001 Nov; 345 (18): 1298-304
    • (2001) N Engl J Med , vol.345 , Issue.18 , pp. 1298-1304
    • Eriksson, B.I.1    Bauer, K.A.2    Lassen, M.R.3
  • 52
    • 0038010814 scopus 로고    scopus 로고
    • Duration of prophylaxis against venous thromboembolism with fondaparinux after hip fracture surgery: A multicenter, randomized, placebo-controlled, double-blind study
    • Jun 9
    • Eriksson BI, Lassen MR, for the PENTasaccharide in HIp-FRActure Surgery Plus (PENTHIFRA Plus) Investigators. Duration of prophylaxis against venous thromboembolism with fondaparinux after hip fracture surgery: a multicenter, randomized, placebo-controlled, double-blind study. Arch Intern Med 2003 Jun 9; 163: 1337-42
    • (2003) Arch Intern Med , vol.163 , pp. 1337-1342
    • Eriksson, B.I.1    Lassen, M.R.2
  • 53
    • 0035283092 scopus 로고    scopus 로고
    • A synthetic pentasaccharide for the prevention of deep-vein thrombosis after total hip replacement
    • Mar 1
    • Turpie AGG, Gallus AS, Hoek JA, et al., for the Pentasaccharide Investigators. A synthetic pentasaccharide for the prevention of deep-vein thrombosis after total hip replacement. N Engl J Med 2001 Mar 1; 344 (9): 619-25
    • (2001) N Engl J Med , vol.344 , Issue.9 , pp. 619-625
    • Agg, T.1    Gallus, A.S.2    Hoek, J.A.3
  • 54
    • 0037048227 scopus 로고    scopus 로고
    • Fondaparinux vs enoxaparin for the prevention of venous thromboembolism in major orthopedic surgery: A meta-analysis of 4 randomized double- blind studies
    • Sep 9
    • Turpie AGG, Bauer KA, Eriksson BI, et al., for the Steering Committees of the Pentasaccharide Orthopedic Prophylaxis Studies. Fondaparinux vs enoxaparin for the prevention of venous thromboembolism in major orthopedic surgery: a meta-analysis of 4 randomized double- blind studies. Arch Intern Med 2002 Sep 9; 162 (16): 1833-40
    • (2002) Arch Intern Med , vol.162 , Issue.16 , pp. 1833-1840
    • Turpie, A.G.G.1    Bauer, K.A.2    Eriksson, B.I.3
  • 55
    • 0037648462 scopus 로고    scopus 로고
    • A meta-analysis of fondaparinux versus enoxaparin in the prevention of venous thromboembolism after major orthopaedic surgery
    • Winter
    • Turpie AGG, Eriksson BI, Lassen MR, et al. A meta-analysis of fondaparinux versus enoxaparin in the prevention of venous thromboembolism after major orthopaedic surgery. J South Orthop Assoc 2002 Winter; 11 (4): 182-8
    • (2002) J South Orthop Assoc , vol.11 , Issue.4 , pp. 182-188
    • Agg, T.1    Eriksson, B.I.2    Lassen, M.R.3
  • 57
    • 0043064005 scopus 로고    scopus 로고
    • Efficacy and safety of fondaparinux in major orthopedic surgery according to the timing of its first administration
    • Aug
    • Turpie A, Bauer K, Eriksson B, et al., on behalf of the Steering Committees of the Pentasaccharide Orthopedic Prophylaxis Studies. Efficacy and safety of fondaparinux in major orthopedic surgery according to the timing of its first administration [letter]. Thromb Haemost 2003 Aug; 90 (2): 364-6
    • (2003) Thromb Haemost , vol.90 , Issue.2 , pp. 364-366
    • Turpie, A.1    Bauer, K.2    Eriksson, B.3
  • 58
    • 2942733862 scopus 로고    scopus 로고
    • Absence of transaminase increase after 4-week administration of fondaparinux (Arixtra®), a new synthetic and selective inhibitor of factor Xa, in the PENTHIFRA-PLUS study
    • abstract no. P2052
    • Lassen M, Bauer KA, Eriksson BI, et al. Absence of transaminase increase after 4-week administration of fondaparinux (Arixtra®), a new synthetic and selective inhibitor of factor Xa, in the PENTHIFRA-PLUS study [abstract no. P2052]. J Thromb Haemost 2003; 1 Suppl. 1: P2052
    • (2003) J Thromb Haemost , vol.1 , Issue.1 SUPPL.
    • Lassen, M.1    Bauer, K.A.2    Eriksson, B.I.3
  • 59
    • 2342426288 scopus 로고    scopus 로고
    • The cost-effectiveness of fondaparinux compared with enoxaparin as prophylaxis against thromboembolism following major orthopedic surgery
    • Oct
    • Gordois A, Posnett J, Borris L, et al. The cost-effectiveness of fondaparinux compared with enoxaparin as prophylaxis against thromboembolism following major orthopedic surgery. J Thromb Haemost 2003 Oct; 1 (10): 2167-74
    • (2003) J Thromb Haemost , vol.1 , Issue.10 , pp. 2167-2174
    • Gordois, A.1    Posnett, J.2    Borris, L.3
  • 60
    • 3242733185 scopus 로고    scopus 로고
    • A cost-effectiveness analysis of fondaparinux sodium compared with enoxaparin sodium as prophylaxis against venous thromboembolism: Use in patients undergoing major orthopaedic surgery
    • Sullivan SD, Davidson BL, Kahn SR, et al. A cost-effectiveness analysis of fondaparinux sodium compared with enoxaparin sodium as prophylaxis against venous thromboembolism: use in patients undergoing major orthopaedic surgery. Pharmacoeconomics 2004; 22 (9): 605-20
    • (2004) Pharmacoeconomics , vol.22 , Issue.9 , pp. 605-620
    • Sullivan, S.D.1    Davidson, B.L.2    Kahn, S.R.3
  • 61
    • 0042278640 scopus 로고    scopus 로고
    • Cost analysis: Fondaparinux versus preoperative and postoperative enoxaparin as venous thromboembolic event prophylaxis in elective hip arthroplasty
    • Apr
    • Wade WE, Spruill WJ, Leslie RB. Cost analysis: fondaparinux versus preoperative and postoperative enoxaparin as venous thromboembolic event prophylaxis in elective hip arthroplasty. Am J Orthop 2003 Apr; 32 (4): 201-5
    • (2003) Am J Orthop , vol.32 , Issue.4 , pp. 201-205
    • Wade, W.E.1    Spruill, W.J.2    Leslie, R.B.3
  • 62
    • 2342522111 scopus 로고    scopus 로고
    • A cost analysis of fondaparinux versus enoxaparin in total knee arthroplasty
    • Spruill WJ, Wade WE, Leslie RB. A cost analysis of fondaparinux versus enoxaparin in total knee arthroplasty. Am J Ther 2004; 11 (1): 3-8
    • (2004) Am J Ther , vol.11 , Issue.1 , pp. 3-8
    • Spruill, W.J.1    Wade, W.E.2    Leslie, R.B.3
  • 63
    • 3242815744 scopus 로고    scopus 로고
    • Cost-effectiveness of fondaparinux (Arixtra®) compared with enoxaparin as prophylaxis against venous thromboembolism following major orthopedic surgery
    • abstract no. P2053. Jul 12-18; Birmingham
    • Annemans L, De Groot K. Cost-effectiveness of fondaparinux (Arixtra®) compared with enoxaparin as prophylaxis against venous thromboembolism following major orthopedic surgery [abstract no. P2053]. 19th Congress of the International Society on Thrombosis and Haemostasis; 2003 Jul 12-18; Birmingham
    • (2003) 19th Congress of the International Society on Thrombosis and Haemostasis
    • Annemans, L.1    De Groot, K.2
  • 64
  • 65
    • 3242810106 scopus 로고    scopus 로고
    • Pharmacoeconomic analysis of fondaparinux for the prevention of thromboembolic events in orthopedic surgical patients
    • Aug
    • Stumpo C, Kahn S, Martineau J, et al. Pharmacoeconomic analysis of fondaparinux for the prevention of thromboembolic events in orthopedic surgical patients [abstract]. Can J Hosp Pharm 2003 Aug; 56 Suppl. 3: 29
    • (2003) Can J Hosp Pharm , vol.56 , Issue.3 SUPPL. , pp. 29
    • Stumpo, C.1    Kahn, S.2    Martineau, J.3
  • 66
    • 3242781304 scopus 로고    scopus 로고
    • Fondaparinux is cost-effective compared with enoxaparin as prophylaxis against venous thromboembolism in patients undergoing surgery for hip replacement
    • [abstract no. 190]. Oct
    • Sullivan SD, Kahn SR, Muntz JE. Fondaparinux is cost-effective compared with enoxaparin as prophylaxis against venous thromboembolism in patients undergoing surgery for hip replacement [abstract no. 190]. Pharmacotherapy 2003 Oct; 23 (10): 1355
    • (2003) Pharmacotherapy , vol.23 , Issue.10 , pp. 1355
    • Sullivan, S.D.1    Kahn, S.R.2    Muntz, J.E.3
  • 67
    • 3242781304 scopus 로고    scopus 로고
    • Fondaparinux is cost-effective compared with enoxaparin as prophylaxis against venous thromboembolism in patients undergoing surgery for knee replacement
    • abstract no. 191. Oct
    • Sullivan SD, Kahn SR, Muntz JE. Fondaparinux is cost-effective compared with enoxaparin as prophylaxis against venous thromboembolism in patients undergoing surgery for knee replacement [abstract no. 191]. Pharmacotherapy 2003 Oct; 23 (10): 1355
    • (2003) Pharmacotherapy , vol.23 , Issue.10 , pp. 1355
    • Sullivan, S.D.1    Kahn, S.R.2    Muntz, J.E.3
  • 68
    • 3242781304 scopus 로고    scopus 로고
    • Fondaparinux is cost-effective compared with enoxaparin as prophylaxis against venous thromboembolism in patients undergoing surgery for hip fracture
    • abstract no. 189. Oct
    • Sullivan SD, Kahn SR, Muntz JE. Fondaparinux is cost-effective compared with enoxaparin as prophylaxis against venous thromboembolism in patients undergoing surgery for hip fracture [abstract no. 189]. Pharmacotherapy 2003 Oct; 23 (10): 1355
    • (2003) Pharmacotherapy , vol.23 , Issue.10 , pp. 1355
    • Sullivan, S.D.1    Kahn, S.R.2    Muntz, J.E.3
  • 69
    • 26344479942 scopus 로고    scopus 로고
    • A cost effectiveness analysis of extending prophylaxis from one week to four weeks with fondaparinux after hip fracture surgery
    • abstract no. 1827. Nov 16
    • Sullivan SD, Kwong L. A cost effectiveness analysis of extending prophylaxis from one week to four weeks with fondaparinux after hip fracture surgery [abstract no. 1827]. Blood 2003 Nov 16; 102 (11 Pt 1): 502a
    • (2003) Blood , vol.102 , Issue.11 PART 1
    • Sullivan, S.D.1    Kwong, L.2
  • 70
    • 26344450472 scopus 로고    scopus 로고
    • Extended prophylaxis treatment with fondaparinux is cost effective compared with enoxaparin after hip fracture surgery
    • abstract no. 5771. Nov 16
    • Sullivan SD, Kwong L. Extended prophylaxis treatment with fondaparinux is cost effective compared with enoxaparin after hip fracture surgery [abstract no. 5771]. Blood 2003 Nov 16; 102 (11 Pt 2): 510b
    • (2003) Blood , vol.102 , Issue.11 PART 2
    • Sullivan, S.D.1    Kwong, L.2
  • 71
    • 26344479942 scopus 로고    scopus 로고
    • The incremental cost per life year saved of extended prophylaxis with fondaparinux versus enoxaparin after hip fracture surgery
    • abstract no. 1826. Nov 16
    • Sullivan SD, Kwong L. The incremental cost per life year saved of extended prophylaxis with fondaparinux versus enoxaparin after hip fracture surgery [abstract no. 1826]. Blood 2003 Nov 16; 102 (11 Pt 1): 502a
    • (2003) Blood , vol.102 , Issue.11 PART 1
    • Sullivan, S.D.1    Kwong, L.2
  • 74
    • 0034961434 scopus 로고    scopus 로고
    • Prevention of venous thromboembolism. International Consensus Statement. Guidelines compiled in accordance with the scientific evidence
    • Mar
    • Nicolaides AN, Breddin HK, Fareed J, et al. Prevention of venous thromboembolism. International Consensus Statement. Guidelines compiled in accordance with the scientific evidence. Int Angiol 2001 Mar; 20 (1): 1-37
    • (2001) Int Angiol , vol.20 , Issue.1 , pp. 1-37
    • Nicolaides, A.N.1    Breddin, H.K.2    Fareed, J.3
  • 75
    • 0036600198 scopus 로고    scopus 로고
    • Two new antithrombotic agents (fondaparinux and ximelagatran) and their implications in anesthesia
    • de Moerloose P, Boehlen F. Two new antithrombotic agents (fondaparinux and ximelagatran) and their implications in anesthesia. Can J Anesth 2002; 49 (6): S5-S10
    • (2002) Can J Anesth , vol.49 , Issue.6
    • De Moerloose, P.1    Boehlen, F.2
  • 77
    • 0035822248 scopus 로고    scopus 로고
    • Extended-duration prophylaxis against venous thromboembolism after total hip or knee replacement: A meta-analysis of the randomised trials
    • Jul
    • Eikelboom JW, Quinlan DJ, Douketis JD. Extended-duration prophylaxis against venous thromboembolism after total hip or knee replacement: a meta-analysis of the randomised trials. Lancet 2001 Jul; 358: 9-15
    • (2001) Lancet , vol.358 , pp. 9-15
    • Eikelboom, J.W.1    Quinlan, D.J.2    Douketis, J.D.3
  • 78
    • 3242762605 scopus 로고    scopus 로고
    • Successful use of Arixtra® in a patient with paroxysmal nocturnal hemoglobinuria, Budd-Chiari syndrome and heparin-induced thrombocytopenia
    • Nov
    • D'Amico EA, Villaça PR, Gualandro SFM, et al. Successful use of Arixtra® in a patient with paroxysmal nocturnal hemoglobinuria, Budd-Chiari syndrome and heparin-induced thrombocytopenia [letter]. J Thromb Haemost 2003 Nov; 1 (11): 2452-3
    • (2003) J Thromb Haemost , vol.1 , Issue.11 , pp. 2452-2453
    • D'Amico, E.A.1    Villaça, P.R.2    Gualandro, S.F.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.