Analysis of the murine 5-HT1A receptor gene promoter in vitro and in vivo

European Journal of Neuroscience

Volumn 20, Issue 2, 2004, Pages 363-374

  Ansorge, Mark ^a   Tanneberger, Cornelia ^a   Davies, Benjamin ^a   Theuring, Franz ^a   Kusserow, Heike ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

LacZ; Reporter gene; Serotonin; Transcription; Transgenic mouse

Indexed keywords

BETA GALACTOSIDASE; MESSENGER RNA; SEROTONIN 1A RECEPTOR;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; FEMALE; GENE CONSTRUCT; GENE EXPRESSION; GENE LOCATION; GENE SEQUENCE; GENETIC ANALYSIS; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RECEPTOR GENE; TRANSGENE; TRANSGENIC ANIMAL; TRANSGENICS;

ANIMALS; BETA-GALACTOSIDASE; CELL COUNT; CELL LINE; CENTRAL NERVOUS SYSTEM; GENE EXPRESSION REGULATION; GENES, REPORTER; IN SITU HYBRIDIZATION; MICE; MICE, TRANSGENIC; NEUROBLASTOMA; PROMOTER REGIONS (GENETICS); RECEPTOR, SEROTONIN, 5-HT1A; REGULATORY SEQUENCES, NUCLEIC ACID; TRANSGENES;

EID: 3242751840     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2004.03472.x     Document Type: Article

References (37)

1. Abdouh, M., Storring, J.M., Riad, M., Paquette, Y., Albert, P.R., Drobetsky, E. & Kouassi, E. (2001) Transcriptional mechanisms for induction of 5-HT1A receptor mRNA and protein in activated B and T lymphocytes. J. Biol. Chem., 276, 4382-4388.
2. Aguzzi, A. & Theuring, F. (1994) Improved in situ beta-galactosidase staining for histological analysis of transgenic mice. Histochemistry, 102, 477-481.
3. Albert, P.R., Lembo, P., Storring, J.M., Charest, A. & Saucier, C. (1996) The 5-HT1A receptor: signaling, desensitization, and gene transcription. Neuropsychopharmacology, 14, 19-25.
4. Barnes, N.M. & Sharp, T. (1999) A review of central 5-HT receptors and their function. Neuropharmacology, 38, 1083-1152.
5. Chalmers, D.T. & Watson, S.J. (1991) Comparative anatomical distribution of 5-HT1A receptor mRNA and 5-HT1A binding in rat brain - a combined in situ hybridisation/in vitro receptor autoradiographic study. Brain Res., 561, 51-60.
6. Clark, A.J., Bissinger, P., Bullock, D.W., Damak, S., Wallace, R., Whitelaw, C.B. & Yull, F. (1994) Chromosomal position effects and the modulation of transgene expression. Reprod. Fertil. Dev., 6, 589-598.
7. Davies, B.J., Pickard, B.S., Steel, M., Morris, R.G. & Lathe, R. (1998) Serine proteases in rodent hippocampus. J. Biol. Chem., 273, 23004-23011.
8. Gravel, M., Di Polo, A., Valera, PB. & Braun, P.E. (1998) Four-kilobase sequence of the mouse CNP gene directs spatial and temporal expression of lacZ in transgenic mice. J. Neurosci. Res., 53, 393-404.
9. Gross, C., Santarelli, L., Brunner, D., Zhuang, X. & Hen, R. (2000) Altered fear circuits in 5-HT(1A) receptor KO mice. Biol. Psychiatry, 48, 1157-1163.
10. Hamprecht, B. (1977) Structural, electrophysiological, biochemical, and pharmacological properties of neuroblastoma-glioma cell hybrids in cell culture. Int. Rev. Cytol., 49, 99-170.
11. Hendricks, T., Francis, N., Fyodorov, D. & Deneris, E.S. (1999) The ETS domain factor Pet-1 is an early and precise marker of central serotonin neurons and interacts with a conserved element in serotonergic genes. J. Neurosci., 19, 10348-10356.
12. Hoyer, D., Clarke, D.E., Fozard, J.R., Hartig, P.R., Martin, G.R., Mylecharane, E.J., Saxena, P.R. & Humphrey, P.P. (1994) International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol Rev., 46, 157-203.
13. Hu, X., Cao, S., Loh, H.H. & Wei, L.N. (1999) Promoter activity of mouse kappa opioid receptor gene in transgenic mouse. Brain Res. MoL. Brain Res., 69, 35-43.
14. Iken, K., Chheng, S., Fargin, A., Goulet, A.C. & Kouassi, E. (1995) Serotonin upregulates mitogen-stimulated B lymphocyte proliferation through 5-HT1A receptors. Cell Immunol., 163, 1-9.
15. Kirchgessner, A.L., Liu, M.T., Raymond, J.R. & Gershon, M.D. (1996) Identification of cells that express 5-hydroxytryptamine1A receptors in the nervous systems of the bowel and pancreas. J. Comp. Neurol., 364, 439-455.
16. Lanfumey, L. & Hamon, M. (2000) Central 5-HT(1A) receptors: regional distribution and functional characteristics. Nucl. Med. Biol., 27, 429-435.
17. Lemonde, S., Morris, S.J., Du Bakish, D.L., Hrdina, P.D., Kushwahal, N. & Albert, P.R. (2000) Abrogated protein-DNA interaction at a C(-1019)G polymorphism in the 5-HT1A receptor gene associated with major depression. Soc. Neurosci. Abstr., 690.695.
18. Lemonde, S., Turecki, G., Du Bakish, D.L., Hrdina, P.D., Bown, C.D., Sequeira, A., Kushwaha, N., Morris, S.J., Basak, A., Ou, X.M. & Albert, P.R. (2003) Impaired repression at a 5-hydroxytryptamine 1A receptor gene polymorphism associated with major depression and suicide. J. Neurosci., 23, 8788-8799.
19. Meijer, O.C., Williamson, A., Dallman, M.F. & Pearce, D. (2000) Transcriptional repression of the 5-HT1A receptor promoter by corticosterone via mineralocorticoid receptors depends on the cellular context. J. Neuroendocrinol., 12, 245-254.
20. Nirenberg, M. (1978) Studies on synapse formation and opiate dependence. Natl Cancer Institute Monogr., 48, 339-342.
21. Ou, X.M., Jafar-Nejad, H., Storring, J.M., Meng, J.H., Lemonde, S. & Albert, P.R. (2000) Novel dual repressor elements for neuronal cell-specific transcription of the rat 5-HT1A receptor gene. J. Biol. Chem., 275, 8161-8168.
22. Ou, X.M., Storring, J.M., Kushwaha, N. & Albert, P.R. (2001) Heterodimerization of mineralocorticoid and glucocorticoid receptors at a novel negative response element of the 5-HT1A receptor gene. J. Biol. Chem., 276, 14299-14307.
23. Parks, C.L. & Shenk, T. (1996) The serotonin 1a receptor gene contains a TATA-less promoter that responds to MAZ and Spl. J. Biol. Chem., 271, 4417-4430.
24. Pazos, A. & Palacios, J.M. (1985) Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors. Brain Res., 346, 205-230.
25. Pompeiano, M., Palacios, J.M. & Mengod, G. (1992) Distribution and cellular localization of mRNA coding for 5-HT1A receptor in the rat brain: correlation with receptor binding. J. Neurosci., 12, 440-453.
26. Ramage, A.G. (2001) Central cardiovascular regulation and 5-hydroxytryptamine receptors. Brain Res. Bull., 56, 425-439.
27. Robinson, D.S., Rickels, K., Feighner, J., Fabre, L.F. Jr, Gammans, R.E., Shrotriya, R.C., Alms, D.R., Andary, J.J. & Messina, M.E. (1990) Clinical effects of the 5-HT1A partial agonists in depression: a composite analysis of buspirone in the treatment of depression. J. Clin. Psychopharmacol., 10, 67S-76S.
28. Rudge, J.S., Eaton, M.J., Mather, P., Lindsay, R.M. & Whittemore, S.R. (1996) CNTF induces raphe neuronal precursors to switch from a serotonergic to a cholinergic phenotype in vitro. Mol Cell Neurosci., 1, 204-221.
29. Sarnyai, Z., Sibille, E.L., Pavlides, C., Fenster, R.J., McEwen, B.S. & Toth, M. (2000) Impaired hippocampal-dependent learning and functional abnormalities in the hippocampus in mice'lacking serotonin (1A) receptors. Proc. Natl. Acad. Sci. USA, 97, 14731-14736.
30. Stamford, J.A., Davidson, C., McLaughlin, D.P. & Hopwood, S.E. (2000) Control of dorsal raphe 5-HT function by multiple 5-HT (1) autoreceptors: parallel purposes or pointless plurality? TINS, 23, 459-465.
31. Storring, J.M., Charest, A., Cheng, P. & Albert, P.R. (1999) TATA-driven transcriptional initiation and regulation of the rat serotonin 5-HT1A receptor gene. J. Neurochem., 12, 2238-2247.
32. Traber, J. & Glaser, T. (1987) 5-HT1A-related anxiolytics. TIPS, 8, 432-437.
33. White, L.A., Eaton, M.J., Castro, M.C., Klose, K.J., Globus, M.Y., Shaw, G. & Whittemore, S.R. (1994) Distinct regulatory pathways control neurofilament expression and neurotransmitter synthesis in immortalized serotonergic neurons. J. Neurosci., 14, 6744-6753.
34. Wissink, S., Meijer, O., Pearce, D., van Der Burg, B. & van Der Saag, P.T. (2000) Regulation of the rat serotonin-1A receptor gene by corticosteroids. J. Biol. Chem., 275, 1321-1326.
35. Wissink, S., van der Burg, B., Katzenellenbogen, B.S. & van der Saag, P.T. (2001) Synergistic activation of the serotonin-1A receptor by nuclear factor-kappa B and estrogen. Mol. Endocrinol., 15, 543-552.
36. Wu, S. & Comings, D.E. (1999) A common C-1018G polymorphism in the human 5-HT1A receptor gene. Psychiatr. Genet., 9, 105-106.
37. Wurch, T., Chastagnier, C., Palmier, C., Colpaert, F.C. & Pauwels, P.J. (1996) A 413 bp region upstream the human 5-HT1A receptor gene is sufficient for its in vitro expression. Neurosci, Res. Commun., 19, 75-82.