Use of blood outgrowth endothelial cells as virus-producing vectors for gene delivery to tumors

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 287, Issue 2 56-2, 2004, Pages

  Jevremovic, Dragan ^a   Gulati, Rajiv ^a   Hennig, Ivo ^a   Diaz, Rosa Maria ^a   Cole, Caroline ^a   Kleppe, Laurel ^a   Cosset, Francois Loic ^b   Simari, Robert D ^a   Vile, Richard G ^a  

^a MAYO CLINIC   (United States)

^b CENTRE INTERNATIONAL DE RECHERCHE EN INFECTIOLOGIE   (France)

Author keywords

Cell carriers; Gene therapy; Stem cells; Viral vectors

Indexed keywords

ADENOVIRUS VECTOR; RETROVIRUS VECTOR; VASCULOTROPIN; VIRUS VECTOR;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CULTURE; CELL ISOLATION; CELL LINEAGE; CHIMERA; CONTROLLED STUDY; CULTURE MODIFIED MONONUCLEAR CELL; DRUG TARGETING; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; MONONUCLEAR CELL; MOUSE; NONHUMAN; OUTGROWTH ENDOTHELIAL CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; TUMOR; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; ADENOVIRIDAE INFECTIONS; ANIMALS; CELL DIFFERENTIATION; CHIMERA; ENDOTHELIUM, VASCULAR; FEMALE; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; MICE; MICE, NUDE; MONOCYTES; NEOPLASM TRANSPLANTATION; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; RETROVIRIDAE; RETROVIRIDAE INFECTIONS;

EID: 3242728550     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00064.2004     Document Type: Article

References (27)

1. Aicher A, Brenner W, Zuhayra M, Badorff C, Massoudi S, Assmus B, Eckey T, Henze E, Zeiher AM, and Dimmeler S. Assessment of the tissue distribution of transplanted human endothelial progenitor cells by radioactive labeling. Circulation 107: 2134-2139, 2003.
2. Asahara T, Masuda H, Takahashi T, Kalka C, Pastore C, Silver M, Kearne M, Magner M, and Isner JM. Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ Res 85: 221-228, 1999.
3. Asahara T, Murohara T, Sullivan A, Silver M, van der Zee R, Li T, Witzenbichler B, Schatteman G, and Isner JM. Isolation of putative progenitor endothelial cells for angiogenesis. Science 275: 964-967, 1997.
4. Assmus B, Schachinger V, Teupe C, Britten M, Lehmann R, Dobert N, Grunwald F, Aicher A, Urbich C, Martin H, Hoelzer D, Dimmeler S, and Zeiher AM. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI). Circulation 106: 3009-3017, 2002.
5. Carmeliet P and Jain RK. Angiogenesis in cancer and other diseases. Nature 407: 249-257, 2000.
6. Chester J, Ruchatz A, Gough M, Crittenden M, Chong H, Loic-Cosset F, Diaz RM, Harrington K, Alvarez-Vallina L, and Vile R. Tumor antigen-specific induction of transcriptionally targeted retroviral vectors from chimeric immune receptor-modified T cells. Nat Biotechnol 20: 256-263, 2002.
7. Crittenden M, Gough M, Chester J, Kottke T, Thompson J, Ruchatz A, Clackson T, Cosset FL, Chong H, Diaz RM, Harrington K, Alvarez Vallina L, and Vile R. Pharmacologically regulated production of targeted retrovirus from T cells for systemic antitumor gene therapy. Cancer Res 63: 3173-3180, 2003.
8. Duisit G, Salvetti A, Moullier P, and Cosset FL. Functional characterization of adenoviral/retroviral chimeric vectors and their use for efficient screening of retroviral producer cell lines. Hum Gene Ther 10: 189-200, 1999.
9. Fernandez Pujol B, Lucibello FC, Gehling UM, Lindemann K, Weidner N, Zuzarte ML, Adamkiewicz J, Elsasser HP, Muller R, and Havemann K. Endothelial-like cells derived from human CD14-positive monocytes. Differentiation 65: 287-300, 2000.
10. Gehling UM, Ergun S, Schumacher U, Wagener C, Pantel K, Otte M, Schuch G, Schafhausen P, Mende T, Kilic N, Kluge K, Schafer B, Hossfeld DK, and Fiedler W. In vitro differentiation of endothelial cells from AC133-positive progenitor cells. Blood 95: 3106-3112, 2000.
11. + cells as cellular vehicles for gene delivery into areas of angiogenesis in a rhesus model. Gene Ther 7: 43-52, 2000.
12. Gulati R, Jevremovic D, Peterson TE, Chatterjee S, Shah V, Vile RG, and Simari RD. Diverse origin and function of cells with endothelial phenotype obtained from adult human blood. Circ Res 93: 1023-1025, 2003.
13. - blood-derived human endothelial cell progenitors. Stem Cells 19: 304-312, 2001.
14. Harrington K, Alvarez-Vallina L, Crittenden M, Gough M, Chong H, Diaz RM, Vassaux G, Lemoine N, and Vile R. Cells as vehicles for cancer gene therapy: the missing link between targeted vectors and systemic delivery? Hum Gene Ther 13: 1263-1280, 2002.
15. Kalka C, Masuda H, Takahashi T, Kalka-Moll WM, Silver M, Kearney M, Li T, Isner JM, and Asahara T. Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization. Proc Natl Acad Sci USA 97: 3422-3427, 2000.
16. Lin Y, Weisdorf DJ, Solovey A, and Hebbel RP. Origins of circulating endothelial cells and endothelial outgrowth from blood. J Clin Invest 105: 71-77, 2000.
17. Lyden D, Hattori K, Dias S, Costa C, Blaikie P, Butros L, Chadburn A, Heissig B, Marks W, Witte L, Wu Y, Hicklin D, Zhu Z, Hackett NR, Crystal RG, Moore MA, Hajjar KA, Manova K, Benezra R, and Rafii S. Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat Med 7: 1194-1201, 2001.
18. Morgenstern JP and Land H. Advanced mammalian gene transfer: high-titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res 18: 3587-3596, 1990.
19. O'Reilly MS, Holmgren L, Shing Y, Chen C, Rosenthal RA, Moses M, Lane WS, Cao Y, Sage EH, and Folkman J. Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 79: 315-328, 1994.
20. + cells identifies a population of functional endothelial precursors. Blood 95: 952-958, 2000.
21. + cells. Br J Haematol 115: 186-194, 2001.
22. Rafii S. Circulating endothelial precursors: mystery, reality, and promise. J Clin Invest 105: 17-19, 2000.
23. Rehman J, Li J, Orschell CM, and March KL. Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factors. Circulation 107: 1164-1169, 2003.
24. Reyes M, Dudek A, Jahagirdar B, Koodie L, Marker PH, and Verfaillie CM. Origin of endothelial progenitors in human postnatal bone marrow. J Clin Invest 109: 337-346, 2002.
25. Schmeisser A, Garlichs CD, Zhang H, Eskafi S, Graffy C, Ludwig J, Strasser RH, and Daniel WG. Monocytes coexpress endothelial and macrophagocytic lineage markers and form cord-like structures in Matrigel under angiogenic conditions. Cardiovasc Res 49: 671-680, 2001.
26. Somia N and Verma IM. Gene therapy: trials and tribulations. Nat Rev Genet 1: 91-99, 2000.
27. Zhao Y, Glesne D, and Huberman E. A human peripheral blood monocyte-derived subset acts as pluripotent stem cells. Proc Natl Acad Sci USA 100: 2426-2431, 2003.