Modulatory effects on myocardial physiology induced by an anti-Trypanosoma cruzi monoclonal antibody involve recognition of major antigenic epitopes from β1-adrenergic and M2-muscarinic cholinergic receptors without requiring receptor cross-linking

Journal of Neuroimmunology

Volumn 153, Issue 1-2, 2004, Pages 99-107

  Cremaschi, Graciela ^a   Fernández, Marisa M ^b   Gorelik, Gabriela ^a   Goin, Juan C ^a   Fossati, Carlos A ^b   Zwirner, Norberto W ^b   Malchiodi, Emilio L ^b  

^a Centre de Estudios Farmacologicos y Botanicos   (Argentina)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Autoimmunity; Chagas' disease; Molecular mimicry; Neurotransmitter receptor

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; EPITOPE; IMMUNOGLOBULIN F(AB) FRAGMENT; MONOCLONAL ANTIBODY; MUSCARINIC M2 RECEPTOR; NEUROTRANSMITTER RECEPTOR; PARASITE ANTIGEN; PROPRANOLOL DERIVATIVE; PROTOZOON ANTIBODY; SYNTHETIC PEPTIDE;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN RECOGNITION; ARTICLE; CHAGAS DISEASE; CROSS LINKING; CROSS REACTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART DISEASE; HEART MUSCLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; TRYPANOSOMA CRUZI;

ADRENERGIC BETA-ANTAGONISTS; ANALYSIS OF VARIANCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, PROTOZOAN; BINDING, COMPETITIVE; CYCLIC AMP; CYCLIC GMP; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; IMMUNOGLOBULIN FAB FRAGMENTS; IODINE ISOTOPES; MICE; MICE, INBRED BALB C; MUSCARINIC ANTAGONISTS; MYOCARDIAL CONTRACTION; PINDOLOL; QUINUCLIDINYL BENZILATE; RADIOIMMUNOASSAY; RADIOLIGAND ASSAY; RECEPTOR, MUSCARINIC M2; RECEPTORS, ADRENERGIC, BETA-1; TITRIMETRY; TRYPANOSOMA CRUZI;

EID: 3242722393     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2004.04.012     Document Type: Article

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