Effects of space flight and -6° bed rest on the neuroendocrine response to metabolic stress in physically fit subjects

Annals of the New York Academy of Sciences

Volumn 1018, Issue , 2004, Pages 562-568

  Kšinantová, Lucia ^a   Koška, Juraj ^a   Martinkovič, Miroslav ^b   Vigaš, Milan ^a   Macho, Ladislav ^a   Kvetňanský, Richard ^a  

^a INSTITUTE OF EXPERIMENTAL ENDOCRINOLOGY   (Slovakia)

^b Hospital of Ministry of Defense   (Slovakia)

Author keywords

Bed rest; Catecholamines; Insulin induced hypoglycemia; Metabolic stress; Space flight

Indexed keywords

ADRENALIN; INSULIN; MONOCOMPONENT INSULIN; NORADRENALIN;

ADRENAL GLAND; ADRENALIN BLOOD LEVEL; ADULT; AIRPLANE PILOT; ASTRONOMY; BED REST; BODY MASS; BODY WEIGHT; BRAIN BLOOD FLOW; CONFERENCE PAPER; CONTROLLED STUDY; FITNESS; GRAVITY; HUMAN; HUMAN EXPERIMENT; HYPOGLYCEMIA; MEDULLA OBLONGATA; METABOLISM; MICROGRAVITY; NEUROENDOCRINE SYSTEM; NORADRENALIN BLOOD LEVEL; NORMAL HUMAN; OXYGEN CONSUMPTION; SIMULATION; SPACE FLIGHT;

EID: 3242685951     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1296.069     Document Type: Conference Paper

References (19)

1. ARBEILLE, P.H., G. GAUQUELIN, J.M. POTTIER, et al. 1992. Results of a 4-week head down tilt with and without LBNP countermeasure: II. Cardiac and peripheral hemodynamics-comparison with a 25-days spaceflight. Aviat. Space Environ. Med. 63: 9-13.
2. LEACH HUNTON, C.S., A.L. GRIGORIEV & Y.V. NATOCHIN. 1998. Fluid and Electrolyte Regulation in Spaceflight. Proceedings of the American Astronautical Society: 81-131. San Diego, CA.
3. HARGENS, A.R. & D.E. WATENPAUGH. 1996. Cardiovascular adaptation to spaceflight. Med. Sci. Sports Exerc. 28: 977-982.
4. VERNIKOS, J., M.F. DALLMAN, L.C. KEIL, et al. 1993. Gender differences in endocrine responses to posture and 7 days of -6 degrees head-down bed rest. Am. J. Physiol. 265: E153-E161.
5. SIGAUDO, D., J.O. FORTRAT, A. MAILLET, et al. 1996. Comparison of 4-day confinement and head-down tilt on endocrine response and cardiovascular variability in humans. Eur. J. Appl. Physiol. 73: 28-37.
6. PAVY-LE TRAON, A., F. LOUISY, P. VASSEUR-CLAUSEN, et al. 1999. Contributory factors to orthostatic intolerance after simulated weightlessness. Clin. Physiol. 19: 360-368.
7. MACHO, L., J. KOŠKA, L. KSINANTOVA, et al. 2003. The response of endocrine system to stress loads during space flight in human subject. Adv. Space Res. 31: 1605-1610.
8. PEULER, J.D. & G.A. JOHNSON. 1977. Simultaneous single isotope radioenzymatic assay of plasma norepinephrine, epinephrine and dopamine. Life Sci. 21: 625-636.
9. BORG, W.P., R.S. SHERWIN, M.J. DURING, et al. 1995. Local ventromedial hypothalamus glucopenia triggers counterregulatory hormone release. Diabetes 44: 180-184.
10. BOLLI, G.B. & C.G. FANELLI. 1999. Physiology of glucose counterregulation to hypoglycaemia. Endocrinol. Metab. Clin. North Am. 28: 467-492.
11. HARDIN, D.S., B. AZZARELLI, J. EDWARDS, et al. 1995. Mechanism of enhanced insulin sensitivity in endurance-trained athletes: effects on blood flow and differential expression of GLUT 4 in skeletal muscles. J. Clin. Endocrinol. Metab. 80: 2437-2446.
12. TREMBLAY, A., D. PINSARD, S. COVENAY, et al. 1990. Counterregulatory response to insulin-induced hypoglycemia in trained and nontrained humans. Metabolism 39: 1138-1143.
13. KVETŇANSKÝ, R., L. MACHO, J. KOŠKA, et al. 2001. Effect of microgravity on plasma catecholamine responses to various Stressors during space flight. J. Gravit. Physiol. 8: P129-P130.
14. MACHO, L., J. KOŠKA, L. KŠINANTOVÁ, et al. 2002. Plasma hormone levels in human subject during stress loads in microgravity and at readadaptation to earth's gravity. J. Gravit. Physiol. 9: P79-P80.
15. LIPMAN, L.R., F. ULVEDAL, J.J. SCHNURE, et al. 1970. Gluco-regulatory hormone response to 2-deoxy-d-glucose infusion in normal subjects at bedrest. Metabolism 19: 980-987.
16. FREY, M.A., T.H. MADER, J.P. BAGIAN, et al. 1993. Cerebral blood velocity and other cardiovascular responses to 2 days of head-down tilt. J. Appl. Physiol. 74: 319-325.
17. KAWAI, Y., G. MURTHY, D.E. WATENPAUGH, et al. 1993. Cerebral blood flow in humans exposed to 24 h of head-down tilt. J. Appl. Physiol. 74: 3046-3051.
18. CHUMAK, O.B. & V.N. KLJUEVA. 1999. Specific aspects of the nervous system and brain blood supply in women during prolonged anti-orthostatic hypokinesia. Aviakosm Ekolog Med. 33: 9-11.
19. CHAUDHURI, A., Y. KANJWAL, P. MOHANTY, et al. 1999. Insulin-induced vasodilatation of internal carotid artery. Metabolism 48: 1470-1473.