Pivotal role of an endogenous tetrahydroisoquinoline, salsolinol, in stress- and suckling-induced release of prolactin

Annals of the New York Academy of Sciences

Volumn 1018, Issue , 2004, Pages 183-191

  Radnai, B ^a   Mravec, B ^b   Bodnar I ^a,b   Kubovcakova, L ^b   Fulop F ^c   Fekete, M I K ^d   Nagy, G M ^a   Kvetnansky, R ^b  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b INSTITUTE OF EXPERIMENTAL ENDOCRINOLOGY   (Slovakia)

^c UNIVERSITY OF SZEGED   (Hungary)

^d INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

PRL release; Salsolinol; Stress; Suckling

Indexed keywords

1 METHYL 3,4 DIHYDROISOQUINOLINE; ALPHA INTERMEDIN; ARGIPRESSIN; BETA ENDORPHIN; CORTICOTROPIN; DEXAMETHASONE; ISOQUINOLINE DERIVATIVE; METIROSINE; PROLACTIN RELEASING FACTOR; SALSOLINOL; TETRAHYDROISOQUINOLINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; BINDING SITE; CONFERENCE PAPER; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; HOMEOSTASIS; HORMONE RELEASE; HYPOPHYSIS INTERMEDIATE LOBE; HYPOTHALAMUS; HYPOTHALAMUS HYPOPHYSIS SYSTEM; IMMOBILIZATION; MALE; NONHUMAN; PROLACTIN RELEASE; RAT; STIMULATION; STRESS; STRUCTURE ANALYSIS; SUCKLING;

ANIMALIA; MAMMALIA;

EID: 3242665139     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1296.021     Document Type: Conference Paper

References (32)

1. FREEMAN, M.E., B. KANYICSKA, A. LÉRÁNT, et al. 2000. Prolactin: structure, function, and regulation of secretion. Physiol. Rev. 80: 1523-1531.
2. MACLEOD, R.M. 1976. Regulation of prolactin secretion. In Frontiers in Neuroendocrinology. L. Martini & W.F. Ganong, Eds.: 169-194. Raven Press. New York.
3. NEILL, J.D. & G.M. NAGY. 1994. Prolactin secretion and its control. In Physiology of Reproduction. E. Knobil & J.D. Neill, Eds.: 1833-1860. Raven Press. New York.
4. THOMAS, G.B., J.T. CUMMINS, B.J. CANNY, et al. 1989. The posterior pituitary regulates prolactin, but not adrenocorticotropin or gonadotropin secretion in sheep. Endocrinology 125: 2204-2211.
5. AVERILL, R.L., D.R. GRATTAN & S.K. NORRIS. 1991. Posterior pituitary lobectomy chronically attenuates the nocturnal surges of prolactin in early pregnancy. Endocrinology 128: 705-709.
6. VECSERNYÉS, M., K. KREMPELS, B.E. TÓTH, et al. 1997. Effect of posterior pituitary denervation (PPD) on prolactin (PRL) and α-melanocyte-stimulating hormone (α-MSH) secretion of lactating rats. Brain Res. Bull. 43: 313-319.
7. SALAND, L.C. 2001. The mammalian pituitary intermediate lobe: an update on innervation and regulation. Brain Res. Bull. 54: 587-593.
8. TÓTH, B.E., K. HOMICSKÓ, B. RADNAI, et al. 2001. Salsolinol is a putative endogenous neuro-intermediate lobe prolactin-releasing factor. J. Neuroendocrinol. 13: 1042-1050.
9. LOOKINGLAND, K.J., J.W. GUNNET, T.W. TONEY, et al. 1990. Comparison of the effects of ether and restraint stress on the activity of tuberoinfundibular dopaminergic neurons in female and male rats. Neuroendocrinology 52: 99-105.
10. MAKARA, G.B. & K.J. KOVÁCS. 1997. Lesioning of the hypothalamic paraventricular nucleus inhibits ether-induced ACTH but not prolactin release. Neurobiology 5: 403-411.
11. MINAMITANI, N., T. MINAMITANI, R.M. LECHAN, et al. 1987. Paraventricular nucleus mediates prolactin secretory responses to restraint stress, ether stress, and 5-hydroxy-L-tryptophan injection in the rat. Endocrinology 120: 860-867.
12. SHIN, S.H. 1979. Prolactin secretion in acute stress is controlled by prolactin releasing factor. Life Sci. 25: 1829-1836.
13. SHIN, S.H. 1980. Physiological evidence for the existence of prolactin releasing factor: stress-induced prolactin secretion is not linked to dopaminergic receptors. Neuroendocrinology 31: 375-379.
14. SHIN, S.H. & H.J. CHI. 1980. Evidence for the existence of physiological prolactin releasing factor and its possible role. Prog. Reprod. Biol. 6: 44-49.
15. VALVERDE, R.C., V. CHIEFFO & S. REICHLIN. 1973. Failure of reserpine to block etherinduced release of prolactin: physiological evidence that stress induced release is not caused by acute inhibition of PIF secretion. Life Sci. 12: 327-335.
16. JURCOVICOVA, J., R. KVETNANSKY, M. DOBRAKOVOVA, et al. 1990. Prolactin response to immobilization stress and hemorrhage: the effect of hypothalamic deafferentations and posterior pituitary denervation. Endocrinology 126: 2527-2533.
17. KEHOE, L., J. JANIK & P. CALLAHAN. 1991. Effects of immobilization stress on tuberoinfundibular dopaminergic (TIDA) neuronal activity and prolactin levels in lactating and non-lactating female rats. Life Sci. 50: 55-63.
18. VÄHÄ-ESKELI, K., R. ERKKOLA, K. IRJALA, et al. 1991. Effect of thermal stress on serum prolactin, cortisol and plasma arginine vasopressin concentration in the pregnant and non-pregnant state. Eur. J. Obstet. Gynecol. Reprod. Biol. 42: 1-8.
19. HOMICSKÓ, K.G., I. KERTÉSZ, B. RADNAI, et al. 2003. Binding site of salsolinol: its properties in different regions of the brain and the pituitary gland of the rat. Neurochem. Int. 42: 19-26.
20. TÓTH, E.B., I. BODNÁR, K.G. HOMICSKÓ, et al. 2002. Physiological role of salsolinol: its hypophysiotrophic function in the regulation of pituitary prolactin secretion. Neurotoxicol. Terratol. 24: 655-666.
21. DEMAREST, K.T., K.E. MOORE & G.D. RIEGLE. 1985. Acute restraint stress decreases tuberoinfundibular dopaminergic neuronal activity: evidence for a differential response in male versus female rats. Neuroendocrinology 41: 504-511.
22. RAGAVAN, V.V. & A.G. FRANTZ. 1981. Opioid regulation of prolactin secretion: evidence for a specific role of beta-endorphin. Endocrinology 109: 1769-1771.
23. ROSSIER, J., E. FRENCH, C. RIVIER, et al. 1988. Stress-induced release of prolactin: blockade by dexamethasone and naloxone may indicate beta-endorphin mediation. Proc. Natl. Acad. Sci. USA 77: 666-669.
24. BÁNKY, Z., G.M. NAGY & B. HALÁSZ. 1994. Analysis of pituitary prolactin and adrenocortical response to ether, formalin or restraint in lactating rats: rise in corticosterone, but no incease in plasma prolactin levels after exposure to stress. Neuroendocrinology 59: 63-71.
25. BARTHA, L., G.M. NAGY, D.T. KIEM, et al. 1991. Inhibition of suckling-induced prolactin (PRL) release by dexamethasone. Endocrinology 129: 635-640.
26. KVETNANSKY, R. & L. MIKULAJ. 1970. Adrenal and urinary catecholamines in rats during adaptation to repeated immobilization stress. Endocrinology 87: 738-743.
27. KACSÓH, B., Z. VERESS, B.E. TÓTH, et al. 1993. Bioactive and immunoreactive variants of prolactin in milk and serum of lactating rats and their pups. J. Endocrinol. 138: 243-257.
28. NAGY, G.M., M. VECSERNYÉS & I. BARNA. 1994. Dehydration decreases plasma level of α-melanocyte stimulating hormone (α-MSH) and attenuates suckling-induces β-endorphin (β-END) but not ACTH response in lactating rats. Neuroendocrinol. Lett. 16: 275-284.
29. NAGY, G.M., T.J. GÖRCS & B. HALÁSZ. 1991. Attenuation of the suckling-induced prolactin release and the high afternoon oscillations of plasma prolactin secretion of lactating rats by antiserum to vasopressin. Neuroendocrinology 54: 566-570.
30. BEN-JONATHAN, N. & R. HNASKO. 2001. Dopamine as a prolactin (PRL) inhibitor. Endocr. Rev. 22: 724-763.
31. SIEGEL, R.A., J. CHOWERS, N. CONFORTI, et al. 1982. Effects of naloxone on basal and stress-induced prolactin secretion, in intact, hypothalamic deafferented, adrenalectomized, and dexamethasone pretreated male rats. Life Sci. 30: 1691-1699.
32. XU, R.K. & S.M. MCCANN. 1989. Differential effects of naloxone on basal and stress-induced release of ACTH and prolactin in the male rat. Life Sci. 45: 1591-1599.