Inhibition of murine cytochrome P4501A by tacrine: In vitro studies

Drug Metabolism and Disposition

Volumn 32, Issue 8, 2004, Pages 805-812

  Peng, Joanna Z ^a,b   Remmel, Rory P ^a   Sawchuk, Ronald J ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLCHOLANTHRENE; CARBON; CHOLINESTERASE INHIBITOR; CYTOCHROME P450 1A; CYTOCHROME P450 1A2; ETHOXYRESORUFIN; HYDROGEN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TACRINE; VELNACRINE; WATER;

AEROBIC METABOLISM; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CATALYSIS; CHEMICAL REACTION; CONTROLLED STUDY; COVALENT BOND; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG INDICATION; DRUG MECHANISM; DRUG METABOLISM; ENZYME INACTIVATION; ENZYME INHIBITION; HYDROGEN BOND; HYDROXYLATION; IN VITRO STUDY; LIVER MICROSOME; MALE; MICHAELIS CONSTANT; NONHUMAN; PRIORITY JOURNAL; RAT; REACTION ANALYSIS;

ANIMALS; AREA UNDER CURVE; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; MALE; RATS; RATS, SPRAGUE-DAWLEY; TACRINE;

ANIMALIA; INSERTION SEQUENCES; MURINAE;

EID: 3242660672     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.32.8.805     Document Type: Article

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