Protection against DNA damage-induced apoptosis by the angiogenic factor thymidine phosphorylase

FEBS Letters

Volumn 580, Issue 5, 2006, Pages 1294-1302

  Jeung, Hei Cheul ^a,b   Che, Xiao Fang ^a   Haraguchi, Misako ^a   Zhao, Hong Ye ^a   Furukawa, Tatsuhiko ^a   Gotanda, Takenari ^a   Zheng, Chun Lei ^a   Tsuneyoshi, Kengo ^a   Sumizawa, Tomoyuki ^a   Roh, Jae Kyung ^b   Akiyama, Shin Ichi ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b Yonsei University College of Medicine   (South Korea)

Author keywords

Akt; Apoptosis; Thymidine phosphorylase

Indexed keywords

ANGIOGENIC FACTOR; COMPLEMENTARY DNA; PHOSPHATIDYLINOSITOL KINASE; PROTEIN KINASE B; THYMIDINE PHOSPHORYLASE;

APOPTOSIS; ARTICLE; CANCER CELL; CELL LINE; CELL PROTECTION; DNA DAMAGE; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYPOXIA; MOLECULE; PRIORITY JOURNAL; STRESS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANGIOGENESIS INDUCING AGENTS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE; DNA DAMAGE; G1 PHASE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; PROMOTER REGIONS (GENETICS); THYMIDINE PHOSPHORYLASE; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 32344452516     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.01.047     Document Type: Article

References (22)

1. T. Furukawa, R. Ikeda, M. Haraguchi, and S. Akiyama Thymidine phosphorylase, a new molecular target for anti-cancer therapy Curr. Top. Biochem. Res. 4 2001 89 95
2. T.S. O'Brien, S.B. Fox, A.J. Dickinson, H. Turley, M. Westwood, A. Moghaddam, K.C. Gatter, R. Bicknell, and A.L. Harris Expression of the angiogenic factor thymidine phosphorylase/platelet-derived endothelial cell growth factor in primary bladder cancers Cancer Res. 56 1996 4799 4804
3. M. Relf, S. Le Jeune, P.A. Scott, S. Fox, K. Smith, R. Leek, A. Moghaddam, R. Whitehouse, R. Bicknell, and A.L. Harris Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis Cancer Res. 57 1997 963 969
4. Y. Takebayashi, K. Yamada, T. Miyadera, T. Sumizawa, T. Furukawa, F. Kinoshita, D. Aoki, H. Okumura, Y. Yamada, S. Akiyama, and T. Aikou The activity and expression of thymidine phosphorylase in human solid tumors Eur. J. Cancer 32A 1996 1227 1232
5. S. Shimaoka, S. Matsushita, T. Nitanda, A. Matsuda, T. Nioh, T. Suenaga, Y. Nishimata, S. Akiba, S. Akiyama, and H. Nishimata The role of thymidine phosphorylase expression in the invasiveness of gastric carcinoma Cancer 88 2000 2220 2227
6. Y. Takebayashi, S. Akiyama, S. Akiba, K. Yamada, K. Miyadera, T. Sumizawa, Y. Yamada, F. Murata, and T. Aikou Clinicopathologic and prognostic significance of angiogenic factor, thymidine phosphorylase, in human colorectal carcinoma J. Natl. Cancer Inst. 88 1996 1110 1117
7. R. Ikeda, T. Furukawa, M. Kitazono, K. Ishitsuka, H. Okumura, A. Tani, T. Sumizawa, M. Haraguchi, M. Komatsu, H. Uchimiya, X.Q. Ren, T. Motoya, K. Yamada, and S. Akiyama Molecular basis for the inhibition of hypoxia-induced apoptosis by 2-deoxy-d-ribose Biochem. Biophys. Res. Commun. 291 2002 806 812
8. S. Mori, S. Takao, R. Ikeda, H. Noma, Y. Mataki, X. Wang, S. Akiyama, and T. Aikou Thymidine phosphorylase suppress Fas-induced apoptotic signal transduction independent of its enzymatic activity Biochem. Biophys. Res. Commun. 295 2002 300 305
9. R. Ikeda, T. Furukawa, R. Mitsuo, T. Noguchi, M. Kitazono, H. Okumura, T. Sumizawa, M. Haraguchi, X.F. Che, H. Uchimiya, Y. Nakajima, X.Q. Ren, S. Oiso, I. Inoue, K. Yamada, and S. Akiyama Thymidine phosphorylase inhibits apoptosis induced by cisplatin Biochem. Biophys. Res. Commun. 301 2003 358 363
10. M. Alvarez-Tejado, S. Naranjo-Suarez, C. Jimenez, A.C. Carrera, M.O. Landazuri, and L. del Peso Hypoxia induces the activation of the phosphatidylinositol 3-kinase/Akt cell survival pathway in PC12 cells J. Biol. Chem. 276 2001 22368 22374
11. T. Suhara, H.S. Kim, L.A. Kirshenbaum, and K. Walsh Suppression of Akt signaling induces Fas ligand expression: involvement of caspase and Jun kinase activation in Akt-mediated Fas ligand regulation Mol. Cell. Biol. 22 2002 680 691
12. S. Takao, S. Akiyama, A. Nakajo, M. Kitazono, S. Natsugoe, K. Miyadera, M. Fukushima, Y. Yamada, and T. Aikou Suppression of metastasis by thymidine phosphorylase inhibitor Cancer Res. 60 2000 5345 5348
13. H. Goto, K. Kohno, S. Sone, S. Akiyama, M. Kuwano, and M. Ono Interferon γ-dependent induction of thymidine phosphorylase/platelet-derived endothelial growth factor through γ-activated sequence-like element in human macrophages Cancer Res. 61 2001 469 473
14. H. Werner, E. Karnieli, F.J. Rauscher, and D. LeRoith Wild-type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor gene Proc. Natl. Acad. Sci. USA 93 1996 8318 8323
15. K. Nishimoto, K. Miyadera, Y. Takebayashi, K. Fukuda, M. Haraguchi, T. Furukawa, Y. Yamada, and S. Akiyama Thymidine phosphorylase activity required for tumor angiogenesis and growth Oncol. Rep. 4 1997 55 58
16. J. Carmichael, W.G. DeGraff, A.F. Gazdar, J.D. Minna, and J.B. Mitchell Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing Cancer Res. 47 1987 936 942
17. M. Kitazono, Y. Takebayashi, K. Ishitsuka, S. Takao, A. Tani, T. Furukawa, K. Miyadera, Y. Yamada, T. Aikou, and S. Akiyama Prevention of hypoxia-induced apoptosis by the angiogenic factor thymidine phosphorylase Biochem. Biophys. Res. Commun. 253 1998 797 803
18. T. Eng-Gan, L. Hallman, G.R. Pilikington, and M.B. Van der Weyden A rapid and simple radiometric assay for thymidine phosphorylase of human peripheral blood cells Clin. Chim. Acta 116 1981 211 236
19. H. Eda, K. Fujimoto, S. Watanabe, M. Ura, A. Hino, Y. Tanaka, K. Wada, and H. Ishitsuka Cytokines induce thymidine phosphorylase expression in tumor cells make them more susceptible of 5′-deoxy-5-fluorouridine Cancer Chemother. Pharmacol. 2 1993 333 338
20. L. Griffiths, G.U. Dachs, R. Bicknell, A.L. Harris, and I.J. Stratford The influence of oxygen tension and pH on the expression of platelet-derived endothelial growth factor/thymidine phosphorylase in human breast tumor cells grown in vitro and in vivo Cancer Res. 57 1997 570 572
21. U. Hunscher, and S. Spadari DNA replication and chemotherapy Physiol. Rev. 74 1994 259 304
22. W. Woessmann, and X.B. Chen Ras-mediated activation of ERK by cisplatin induces cell death independently of p53 in osteosarcoma and neuroblastoma cell lines Cancer Chemother. Pharmacol. 50 2002 397 404