Effect of Danchunwhangagam on LPS or DFX-induced cytokine production in peripheral mononuclear cells of cerebral infarction patients

Immunopharmacology and Immunotoxicology

Volumn 27, Issue 4, 2005, Pages 683-696

  Kim, Su Jin ^a,b   Jeong, Hyun Ja ^a   Moon, Phil Dong ^a,c   Lee, Kang Min ^b   Moon, Byung Soon ^c   Myung, Noh Yil ^c   An, Nyeon Hyung ^c   Hong, Seung Heon ^c   Um, Jae Young ^a   Kim, Hyung Min ^a  

^a Kyung Hee University   (South Korea)

^b Chonbuk National University   (South Korea)

^c Wonkwang University   (South Korea)

Author keywords

Cerebral Infarction; Danchunwhangagam; Inflammatory Cytokines; Peripheral Blood Mononuclear Cells

Indexed keywords

CYTOKINE; DANCHUNWHANGAGAM; DEFEROXAMINE; HERBACEOUS AGENT; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN INFARCTION; CELL STIMULATION; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG MECHANISM; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOPHARMACOLOGY; PATHOPHYSIOLOGY; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; SUPERNATANT;

AGED; CELLS, CULTURED; CEREBRAL INFARCTION; CYTOKINES; DEFEROXAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; FEMALE; HUMANS; INTERLEUKINS; KOREA; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; MALE; MEDICINE, ORIENTAL TRADITIONAL; MIDDLE AGED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 32344452212     PISSN: 08923973     EISSN: 15322513     Source Type: Journal    
DOI: 10.1080/08923970500418950     Document Type: Article

References (24)

1. Stoll, G.; Jander, S.; Schroeter, M. Inflammation and glial responses in ischemic brain lesions. Prog. Neurobiol. 1998, 56, 149-171.
2. Ross, R. Atherosclerosis: an inflammatory disease. N. Engl. J. Med. 1999, 340, 115-126.
3. Woods, A.; Brull, D.J.; Humphries, S.E.; Montgomery, H.E. Genetics of inflammation and risk of coronary artery disease: the central role of interleukin-6. Eur. Heart J. 2000, 21, 1574-1583.
4. Shohami, E.; Ginis, I.; Allenbeck, J.M. Dual role of tumor necrosis factor alpha in brain injury. Cytokine Growth Factor Rev. 1999, 10, 119-130.
5. Hallenbeck, J.M. The many faces of tumor necrosis factor in stroke. Nat. Med. 2002, 8, 1363-1368.
6. Kawamata, T.; Dietrich, W.D.; Schallert, T.; Gotts, J.E.; Cocke, R.R.; Benowitz, L.I.; Finklestein, S.P. Intracisternal basic fibroblast growth factor enhances functional recovery and up-regulates the expression of a molecular marker of neuronal sprouting following focal cerebral infarction. Proc. Natl. Acad. Sci. USA 1997, 94, 8179-8184.
7. Touzani, O.; Boutin, H.; Chuquet, J.; Rothwel, L. N. Potential mechanisms of interleukin-1 involvement in cerebral ischaemia. J. Neuroimmunol. 1999, 100, 203-215.
8. Rothwell, N.J.; Luheshi, G.N. Interleukin 1 in the brain: biology, pathology and therapeutic target. Trends Neurosci 2000, 23, 618-625.
9. Wang, X.; Yue, T.L.; Barone, F.C.; White, R.F.; Gagnon, R.C.; Feuerstein, G.Z. Concomitant cortical expression of TNF-α and IL-1β mRNAs follows early response gene expression in transient focal ischemia. Mol. Chem. Neuropathol. 1994, 23, 103-114.
10. Hillhouse, E.W.; Kida, S.; Iannotti, F. Middle cerebral artery occlusion in the rat causes a biphasic production of immunoreactive interleukin-1beta in the cerebral cortex. Neurosci. Lett. 1998, 249, 177-179.
11. Zhang, Z.; Chopp, M.; Goussev, A.; Powers, C. Cerebral vessels express interleukin 1beta after focal cerebral ischemia. Brain Res 1998, 784, 210-217.
12. Benveniste, E.N. Inflammatory cytokines within the central nervous system: sources, function, and mechanism of action. Am. J. Physiol.-Cell Physiol 1992, 263, 116-122.
13. Vila, N.; Reverter, J.C.; Yague, J.; Chamorro, A. Interaction between interleukin-6 and the natural anticoagulant system in acute stroke. J. Interferon Cytokine Res. 2000, 20, 325-329.
14. Matsumoto, T.; Ikeda, K.; Mukaida, N.; Harada, A.; Matsumoto, Y.; Yamashita, J.; Matsushima, K. Prevention of cerebral edema and infarct in cerebral reperfusion injury by an antibody to interleukin-8. Lab. Invest. 1997, 77, 119-125.
15. Weiss, G.; Fuchs, D.; Hausen, A.; Reibnegger, G.; Werner, E.R.; Werner-Felmayer, G.; Wachter, H. Iron modulates interferon-gamma effects in the human myelomonocytic cell line THP-1. Exp. Hematol. 1992, 20, 605-610.
16. Jeong, H.J.; Chung, H.S.; Lee, B.R.; Kim, S.J.; Yoo, S.J.; Hong, S.H.; Kim, H.M. Expression of proinflammatory cytokines via HIF-1alpha and NF-kappaB activation on desferrioxamine-stimulated HMC-1 cells. Biochem. Biophys. Res. Commun. 2003, 306, 805-811.
17. Dai, L.J.; Hou, J.; Cai, H.R. Experimental study on treatment of pulmonary fibrosis by Chinese drugs and integrative Chinese and Western medicine. Zhongguo Zhong Xi Yi Jie He Za Zhi 2004, 24, 130-132.
18. Shi, Y.M.; Wu, Q.Z. Idiopathic thrombocytopenic purpura in children treated with replenishing qi and tonifying kidney and the changes in thrombocyte aggregative function. Zhong Xi Yi Jie He Za Zhi 1991, 11, 14-16.
19. Kim, I.T.; Park, Y.M.; Shin, K.M.; Ha, J.; Choi, J.; Jung, H.J.; Park, H.J.; Lee, K.T. Anti-inflammatory and anti-nociceptive effects of the extract from Kalopanax pictus, Pueraria thunbergiana and Rhus verniciflua. J. Ethnopharmacol. 2004, 94, 165-173.
20. Tomimoto, H.; Akiguchi, I.; Wakita, H.; Kinoshita, A.; Ikemoto, A.; Nakamura, S.; Kimura, J. Glial expression of cytokines in the brains of cerebrovascular disease patients. Acta Neuropathologica. 1996, 92, 281-287.
21. Fassbender, K.; Rossol, S.; Kammer, T.; Daffertshofer, M.; Wirth, S.; Dollman, M. Proinflammatory cytokines in serum of patients with acute cerebral ischemia: kinetics of secretion and relation to the extent of brain damage and outcome of disease. J. Neurosci. 1994, 19, 135-139.
22. Ferrarese, C.; Mascarucci, P.; Zoia, C.; Cavarretta, R.; Frigo, M.; Begni, B. Increased cytokine release from peripheral blood cells after acute stroke. J. Cereb. Blood Flow Metab. 1999, 6, 1004-1009.
23. Chertov, O.; Michiel, D.F.; Xu, L.; Wang, J.M.; Tani, K.; Murphy, W.J.; Longo, D.L.; Taub, D.D.; Oppenheim, J.J. Identification of defensin-1, defensin-2, and CAP37/Azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils. J. Biol. Chem. 1996, 271, 2935-2940.
24. Taub, D.D.; Anver, M.; Oppenheim, J.J.; Longo, D.L.; Murphy, W.J. T lymphocyte recruitment by interleukin-8 (IL-8). J. Clin. Invest. 1996, 97, 1931-1941.