A convenient method for in situ generation of I2 using CuSO 4/NaI and its applications to the deprotection of acetals, etherifications and iodolactonizations

Synlett

Volumn , Issue 2, 2006, Pages 215-218

  Bailey, Aaron D ^a   Cherney, Steven M ^a   Anzalone, Peter W ^a   Anderson, Erin D ^a   Ernat, Justin J ^a   Mohan, Ram S ^a  

^a ILLINOIS WESLEYAN UNIVERSITY   (United States)

Author keywords

Acetals; Chemoselectivity; Ethers; Iodine; Lactones

Indexed keywords

ACETAL DERIVATIVE; COPPER SULFATE; IODINE; SODIUM IODIDE;

ARTICLE; CATALYSIS; ETHERIFICATION; IODOLACTONIZATION; LACTONIZATION; PH; SYNTHESIS;

EID: 32344437736     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.2110/palo.2005-p05-51e     Document Type: Article

References (31)

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20. 2 color was not reported.
21. 4). The organic layer was concentrated on a rotary evaporator to yield 0.268 g (78%) of vanillin acetate as a white solid that was found to be at least 98% pure.
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23. 3): δ = -4.5, 18.1, 25.5, 120.4, 130.3, 131.8, 161.4, 190.7.
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29. Although solid copper waste is produced in this method, the solids are collected by suction filtration and hence easily contained. No toxic aqueous waste stream is generated.
30. 13C NMR analysis.
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