Inhaled insulin is better absorbed when administered as a dry powder compared to solution in the presence or absence of alkylglycosides

Pharmaceutical Research

Volumn 23, Issue 1, 2006, Pages 138-147

  Hussain, Alamdar ^a   Majumder, Quamrul H ^b   Ahsan, Fakhrul ^a  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b Barr Laboratories Inc   (United States)

Author keywords

Alkylglycosides; Bronchoalveolar lavage; Dry powder; Inhalation; Insulin

Indexed keywords

DECYL BETA DEXTRO MALTOSIDE; DODECYL BETA DEXTRO MALTOSIDE; GLYCOSIDE; MALTOSE; OCTYL BETA DEXTRO MALTOSIDE; OCTYLMALTOSIDE; RECOMBINANT HUMAN INSULIN; TETRADECYL BETA DEXTRO MALTOSIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG FORMULATION; DRUG SAFETY; DRY POWDER; ENZYME ACTIVITY; FREEZE DRYING; GLUCOSE BLOOD LEVEL; HYDROPHOBICITY; INFRARED SPECTROSCOPY; INHALER; INSULIN BLOOD LEVEL; LUNG INJURY; LUNG LAVAGE; MALE; NONHUMAN; POWDER INHALER; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY;

ADMINISTRATION, INHALATION; ANIMALS; AREA UNDER CURVE; BRONCHOALVEOLAR LAVAGE FLUID; CHEMISTRY, PHARMACEUTICAL; EXCIPIENTS; GLYCOSIDES; HYPOGLYCEMIC AGENTS; INSULIN; LUNG; MALE; MICROSCOPY, ELECTRON, SCANNING; NEBULIZERS AND VAPORIZERS; PHARMACEUTICAL SOLUTIONS; POWDERS; RATS; RATS, SPRAGUE-DAWLEY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 32244439546     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11095-005-8926-9     Document Type: Article

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