Diagnosis of invasive aspergillosis and mucormycosis in immunocompromised patients by seminested PCR assay of tissue samples

European Journal of Clinical Microbiology and Infectious Diseases

Volumn 25, Issue 1, 2006, Pages 8-13

  Rickerts, V ^a   Just Nubling G ^a   Konrad, F ^b   Kern, J ^b   Lambrecht, E ^a   Bohme A ^a   Jacobi, V ^a   Bialek, R ^b  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

Aspergillosis; Histopathology; PCR; Zygomycosis

Indexed keywords

FUNGAL DNA;

ADULT; ARTICLE; ASPERGILLOSIS; ASPERGILLUS; BIOPSY; CLINICAL ARTICLE; CONTROLLED STUDY; DNA DETERMINATION; FEMALE; FUNGAL CELL CULTURE; FUNGAL GENE; FUNGUS IDENTIFICATION; GENE AMPLIFICATION; GENE SEQUENCE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNE DEFICIENCY; MALE; MOULD; MUCORMYCOSIS; MYCOSIS; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TISSUE SECTION; YEAST; ZYGOMYCETES;

ADULT; ASPERGILLOSIS; ASPERGILLUS; CUNNINGHAMELLA; DNA PRIMERS; DNA, FUNGAL; DNA, MITOCHONDRIAL; FEMALE; HUMANS; IMMUNOCOMPROMISED HOST; MALE; MICROBIOLOGICAL TECHNIQUES; MIDDLE AGED; MUCORALES; MUCORMYCOSIS; POLYMERASE CHAIN REACTION; RESPIRATORY TRACT INFECTIONS; RETROSPECTIVE STUDIES; RNA, RIBOSOMAL, 18S; TRICHOSPORON;

EID: 32144462624     PISSN: 09349723     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10096-005-0078-7     Document Type: Article

References (32)

1. Fridkin S, Jarvis W (1996) Epidemiology of nosocomial fungal infections. Clin Microbiol Rev 9:499-511
2. Groll A, Shah PM, Mentzel C et al (1996) Trends in postmortem epidemiology of invasive fungal infections at a university hospital. J Infect 33:23-32
3. Marr K, Carter R, Crippa F et al (2002) Epidemiology and outcome of mould infections in hematopoietic stem cell transplant recipients. Clin Infect Dis 34:909-917
4. Sun QN, Fothergill AW, McCarthy DI et al (2002) In vitro activities of posaconazole, itraconazole, voriconazole, amphotericin B, and fluconazole against 37 clinical isolates of zygomycetes. Antimicrob Agents Chemother 46:1581-1582
5. Ascioglu S, Rex J, de Pauw B et al (2002) Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus. Clin Infect Dis 34:7-14
6. Nosari A, Anghilieri M, Carrafiello G, et al (2003) Utility of percutaneous lung biopsy for diagnosing filamentous fungal infections in hematologic malignancies. Haematologica 88:1405-1409
7. Denning D (1998) Invasive aspergillosis. Clin Infect Dis 26:781-805
8. Ribes J, Vanover-Sams C, Baker D (2000) Zygomycetes in human disease. Clin Microbiol Rev 13:236-301
9. Bialek R, Fischer J, Feucht A et al (2001) Diagnosis and monitoring of murine histoplasmosis by a nested PCR assay. J Clin Microbiol 29:1506-1509
10. Loeffler J, Kloepfer K, Hebart H et al (2001) Polymerase chain reaction detection of Aspergillus DNA in experimental models of invasive aspergillosis. J Infect Dis 185:1203-1206
11. Bialek R, Konrad F, Kern J et al (2005) PCR-based identification and discrimination of mucormycosis and aspergillosis in paraffin-embedded tissue. J Clin Pathol 58:1180-1184
12. Bretagne S, Costa J, Marmorat-Khuong A et al (1995) Detection of Aspergillus species DNA in bronchoalveolar lavage samples by competitive PCR. J Clin Microbiol 33: 1164-1168
13. Martino R, Subriá M, Rovira M et al (2002) Invasive fungal infections after allogeneic peripheral blood stem cell transplantation: incidence and risk factors in 395 patients. Br J Haematol 116:475-482
14. Herbrecht R, Denning D, Patterson T et al (2002) Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis. N Engl J Med 347:408-415
15. Dannaoui E, Borel E, Persat F et al (2000) Amphotericin B resistance of Aspergillus terreus in a murine model of disseminated aspergillosis. J Med Microbiol 49:601-606
16. Iwen P, Rupp M, Langnas A et al (2003) Invasive pulmonary aspergillosis due to Aspergillus terreus: 12-year experience and review of the literature. Clin Infect Dis 26:1092-1097
17. Kim K, Lee M, Kim J et al (2002) Importance of open lung biopsy in the diagnosis of invasive pulmonary aspergillosis in patients with hematologic malignancies. Am J Hematol 71:75-79
18. Pidhorecky I, Urschel J, Anderson T (2003) Resection of invasive pulmonary aspergillosis in immunocompromised patients. Ann Surg Oncol 7:312-317
19. Yamazaki T, Kume H, Murase S et al (1999) Epidemiology of visceral mycoses: analysis of data in annual of the pathological autopsy cases in Japan. J Clin Microbiol 37:1732-1738
20. Gómez-López A, Cuenca-Estrella M, Monzón A et al (2001) In vitro susceptibility of clinical isolates of Zygomycota to amphotericin B, flucytosine, itraconazole and voriconazole. J Antimicrob Chemother 48:919-921
21. Pfaller M, Marco F, Messer S et al (1998) In vitro activity of two echinocandin derivatives, LY303366 and MK-0991 (L-743,792), against clinical isolates of Aspergillus, Fusarium, Rhizopus and other filamentous fungi. Diagn Microbiol Infect Dis 30:251-255
22. Marty FM, Cosimi LA, Baden LR (2004) Breakthrough zygomycosis after voriconazole treatment in recipients of hematopoietic stem-cell transplants. New Engl J Med 26: 950-952
23. Rickerts V, Böhme A, Viertel A et al (2000) Cluster of pulmonary infections caused by Cunninghamella bertholletiae in immunocompromised patients. Clin Infect Dis 31:910-913
24. Rickerts V, Loeffler J, Böhme A et al (2001) Diagnosis of disseminated zygomycosis using a polymerase chain reaction assay. Eur J Clin Microbiol Infect Dis 20:744-745
25. Herbrecht R, Letscher-Bru R, Bowden R et al (2001) Treatment of 21 cases of invasive mucormycosis with amphotericin B colloidal dispersion. Eur J Clin Microbiol Infect Dis 20: 460-466
26. Dannaoui E, Meletiadis J, Mouton J et al (2003) In vitro susceptibilities of zygomycetes to conventional and new antifungals. J Antimicrob Chemother 51:45-52
27. Kontoyiannis D, Wessel W, Bodey G et al (2000) Zygomycosis in the 1990s in a tertiary-care cancer center. Clin Infect Dis 30:851-856
28. Imhof A, Schaer C, Schoedon G et al (2003) Rapid detection of pathogenic fungi from clinical specimens using LightCycler Real Time Fluorescence PCR. Eur J Clin Microbiol Infect Dis 22:558-560
29. Willinger B, Obradovic A, Selitsch B et al (2003) Detection and identification of fungi from fungus balls of the maxillary sinus by molecular techniques. J Clin Microbiol 41:581-585
30. Bialek R, Gonzalez GM, Begerow D, Zelck UE (2005) Coccidioidomycosis and blastomycosis: advances in molecular diagnosis (related articles, links). FEMS Immunol Med Microbiol 45:355-360
31. Bialek R, Weiss M, Bekure-Nemariam K et al (2002) Detection of Cryptococcus neoformans DNA in tissue samples by nested and real-time PCR assays. Clin Diagn Lab Immunol 9:461-469
32. Hayden RT, Qian X, Procop GW et al (2002) In situ hybridization for the identification of filamentous fungi in tissue section. Diagn Mol Pathol 11:119-126